scholarly journals Near Infrared Spectroscopy: Basic principles and use in tablet evaluation

2017 ◽  
Vol 6 (2) ◽  
pp. 2006 ◽  
Author(s):  
Hiren J. Patel

The continuous preference of the oral route for the delivery of the drugs has led the ongoing research in the field of oral delivery. With emergence of Near-infrared spectroscopy (NIRS) as a fast and non-destructive analytical method, researchers have used NIRS for non-destructive evaluation of tablets. This review looks at the basics, theoretical aspects of NIRS, qualitative and quantitative treatment of sample spectra for better understanding of NIRS in tablet evaluation. Use of NIRS in tablet evaluation is discussed in detail with focus on evaluation of tablet hardness, content uniformity and dissolution with use of NIRS. In addition to advantages and limitation of use of NIRS, the current regulatory status and exploration of NIRS as a PAT tool is discussed in the later part of the review.

2021 ◽  
pp. 101189
Author(s):  
Alin Khaliduzzaman ◽  
Ayuko Kashimori ◽  
Tetsuhito Suzuki ◽  
Yuichi Ogawa ◽  
Naoshi Kondo

2015 ◽  
Vol 671 ◽  
pp. 356-362 ◽  
Author(s):  
Zhi Feng Chen ◽  
Yuan Quan Hong ◽  
Chang Jiang Wan ◽  
Lian Ying Zhao

A fast non-destructive method of detection of wool content in blended fabrics was studied based on Near Infrared spectroscopy technology in order to avoid the time-consuming, tedious work and the destruction of samples in the traditional inspection. 621 wool/nylon, wool/polyester and wool/nylon/polyester blended fabrics were taken as research objects. To get the wool content, we established the wool near-infrared quantitative model by partial least squares (PLS) method after analyzing the color and composition of the samples. For verifying the validity and practicability of the model, 100 samples were chosen as an independent validation set. The variance analysis shows that there is no significant difference between Near Infrared fast detection method and national standard method (GB/T2910-2009),which indicates that this method is expected to be a means of fast non-destructive detection and will have extensive application future in the field of wool content detection.


2021 ◽  
Vol 305 ◽  
pp. 124796
Author(s):  
A. Watanabe ◽  
S. Tokuda ◽  
Y. Mizuta ◽  
S. Miyamoto ◽  
T. Nakanishi ◽  
...  

LWT ◽  
2019 ◽  
Vol 103 ◽  
pp. 101-107 ◽  
Author(s):  
Lívia C. Carvalho ◽  
Marcondes L. Leite ◽  
Camilo L.M. Morais ◽  
Kássio M.G. Lima ◽  
Gustavo H.A. Teixeira

Author(s):  
Olaoluwa Omoniyi Olarewaju ◽  
Lembe Samukelo Magwaza ◽  
Helene Nieuwoudt ◽  
Carlos Poblete-Echeverría ◽  
Olaniyi Amos Fawole ◽  
...  

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