scholarly journals The Influence of AIMOHit to Medication Adherence of Hypertension Patients in Malang

2021 ◽  
Vol 9 (1) ◽  
pp. 1-9
Author(s):  
Alfrina Hany ◽  
◽  
Klara Yunita Inuq Thomas ◽  
Ahmad Hasyim Wibisono
Keyword(s):  
Treatment Group ◽  
Health Center ◽  
Statistical Test ◽  
Term Treatment ◽  
Control Group ◽  
P Value ◽  
Test Results ◽  
Hypertensive Patients ◽  
Long Term Treatment

The long-term treatment that a hypertensive patient has to undergo has resulted in the patient becoming non-adherent. Patients accidentally not taking medication is one of the causes of non-adherence. A method for preventing non-compliance due to forgetting to take medication is important. The AIMOHit application which means "Let's Remember to Take Hypertension Medication" is designed to support hypertensive patients to be compliant in taking medication. This study aims to identify the effect of AIMOHit application on adherence to taking medication for hypertensive patients in the Janti Health Center, Malang City. A total of 52 hypertensive patients were willing to be the sample in this study. The instrument used was the AIMOHit application on the Android smartphone for the treatment group and the checklist for the control group. It is known that the adherence statistical test showed that the average adherence to taking medication in the treatment group was higher (32.17) than the control group (20.83). Meanwhile, the Mann Whitney test results obtained p value = 0.000 (<0.05). The conclusion is that there is a significant effect of AIMOHit application on compliance with taking medication for hypertension sufferers in the Janti Health Center, Malang City.

scholarly journals Comparative therapeutic evaluation of 308 nm monochromatic excimer light in combination with calcipotriol ointment vs 308 nm monochromatic excimer light alone in palmoplantar psoriasis

2019 ◽  
Vol 5 (1) ◽  
pp. 32
Author(s):  
Chandrakant B. Poulkar ◽  
Nitin D. Chaudhari ◽  
Swapna S. Khatu ◽  
Shilpa L. Patwekar
Keyword(s):  
Treatment Group ◽  
Day Treatment ◽  
Term Treatment ◽  
Self Control ◽  
Treatment Modalities ◽  
Control Group ◽  
Topical Steroids ◽  
External Application ◽  
Long Term Treatment

<p class="abstract"><strong>Background:</strong> Palmoplantar psoriasis is difficult to treat and often recalcitrant to traditional treatment modalities like topical steroids, anthralin, calcipotriol, methotrexate, cyclosporine, NB-UVB and PUVA. This study was aimed to compare efficacy of 308 nm monochromatic excimer light (MEL) in combination with calcipotriol ointment to 308 nm MEL alone in treatment of palmoplantar psoriasis.</p><p class="abstract"><strong>Methods:</strong> This self-control study was conducted in 30 patients of palmoplantar psoriasis. Right side was treated with 308 nm MEL, 2 times/week, at meantime calcipotriol ointment was applied externally, 2 times/day (treatment group); the left side was treated with 308 nm MEL alone, 2 times/week (control group). Erythema, scaling, induration and fissuring (ESIF) score and cumulative doses of 308 nm MEL were assessed before treatment and on weeks 2, 4 and 6 after initiation of treatment.<strong></strong></p><p class="abstract"><strong>Results:</strong> All 30 patients completed the treatment. ESIF scores on week 2, week 4, and week 6 in treatment group were significantly lower than control group (p&lt;0.01). The average cumulative MEL dose in treatment group at the end of trial was 8.12±1.72 J/cm<sup>2</sup>, which was significantly lower than in control group 12.76±1.92 J/cm<sup>2</sup> (p&lt;0.01).</p><p class="abstract"><strong>Conclusions:</strong> Treatment of palmoplantar psoriasis with 308 nm MEL in combination with external application of calcipotriol ointment can improve long-term treatment efficacy, decrease cumulative doses, and adverse effects induced by MEL irradiations.</p>

Diuretics ??? a risk in the long-term treatment of hypertensive patients?

1988 ◽  
Vol 6 (11) ◽  
pp. 925-930 ◽  
Author(s):  
Antoon Amery ◽  
Willem Birkenh??ger ◽  
Christopher Bulpitt ◽  
Denis Clement ◽  
Peter de Leeuw ◽  
...  
Keyword(s):  
Term Treatment ◽  
Hypertensive Patients ◽  
Long Term Treatment

scholarly journals Mitochondrial and Oxidative Impacts of Short and Long-term Administration of HAART on HIV Patients

2020 ◽  
Vol 15 (2) ◽  
pp. 110-124
Author(s):  
Joy E. Ikekpeazu ◽  
Oliver C. Orji ◽  
Ikenna K. Uchendu ◽  
Lawrence U.S. Ezeanyika
Keyword(s):  
Treatment Group ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Hiv Patients ◽  
Long Term Treatment ◽  
Term Administration ◽  
Short And Long Term ◽  
One Year

Background and Objective: There may be a possible link between the use of HAART and oxidative stress-related mitochondrial dysfunction in HIV patients. We evaluated the mitochondrial and oxidative impacts of short and long-term administration of HAART on HIV patients attending the Enugu State University Teaching (ESUT) Hospital, Enugu, Nigeria following short and long-term therapy. Methods: 96 patients categorized into four groups of 24 individuals were recruited for the study. Group 1 comprised of age-matched, apparently healthy, sero-negative individuals (the No HIV group); group 2 consisted of HIV sero-positive individuals who had not started any form of treatment (the Treatment naïve group). Individuals in group 3 were known HIV patients on HAART for less than one year (Short-term treatment group), while group 4 comprised of HIV patients on HAART for more than one year (Long-term treatment group). All patients were aged between 18 to 60 years and attended the HIV clinic at the time of the study. Determination of total antioxidant status (TAS in nmol/l), malondialdehyde (MDA in mmol/l), CD4+ count in cells/μl, and genomic studies were all done using standard operative procedures. Results: We found that the long-term treatment group had significantly raised the levels of MDA, as well as significantly diminished TAS compared to the Short-term treatment and No HIV groups (P<0.05). In addition, there was significantly elevated variation in the copy number of mitochondrial genes (mtDNA: D-loop, ATPase 8, TRNALEU uur) in the long-term treatment group. Interpretation and Conclusion: Long-term treatment with HAART increases oxidative stress and causes mitochondrial alterations in HIV patients.

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