Depression and the Reporting of Diabetes Symptoms

The relationship of diabetes symptoms to current mood and general metabolic control was studied. Symptoms commonly associated with poorly controlled diabetes (e.g., thirst, polyuria, weight loss) were measured in 114 patients with diabetes mellitus (type 1 = 57, type 2 = 57). Scores for these individual symptoms were correlated with glycosylated hemoglobin (HbA1) and depression as measured by the Beck Depression Inventory (BDI). HbA1 was poorly correlated ( r < 0.2) with nine of the eleven symptoms and made a significant independent contribution only to the reporting of polyuria ( p = 0.04). In contrast, depression was moderately correlated with nine symptoms and had a significant effect on the reporting of two of three hyperglycemic symptoms, five of six hypoglycemic symptoms, and both nonspecific symptoms of poor control ( p < 0.05 for each). We conclude that many reported symptoms often attributed to diabetes are more related to depressive mood than to a conventional clinical measure of blood glucose control. Diabetes symptoms may be unreliable indicators of poor metabolic control when features suggestive of depression are present.

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Association Between Sense of Coherence and Metabolic Control in People with Diabetes Mellitus Type 2

European Scientific Journal ESJ ◽

10.19044/esj.2018.v14n15p90 ◽

2018 ◽

Vol 14 (15) ◽

pp. 90

Author(s):

Mónica Susana Guevara C. ◽

Marcelo Nicolalde ◽

Amparo Amoroso ◽

Patricia Chico ◽

Nicole Mora ◽

...

Keyword(s):

Diabetes Mellitus ◽

Metabolic Control ◽

Sense Of Coherence ◽

Glycosylated Hemoglobin ◽

Cross Sectional Study ◽

Chronic Complications ◽

Cross Sectional ◽

Patients With Diabetes ◽

The Relationship

The chronic complications of type 2 diabetes mellitus are related to the level of metabolic control and often inadequate control is achieved, so there is the possibility of exploring other therapeutic options. The sense of coherence makes it possible to face several stressors and maintain health. This research aimed to explore whether people with diabetes mellitus 2 and high values in the sense of coherence scale have better metabolic control. Cross-sectional study in patients with diabetes 2. The value of the coherence sense scale and HbA1c glycosylated hemoglobin was determined. A multivariate analysis was carried out by conglomerates and the average HbA1c ratio was established for these groups. 163 subjects participated with an average of 59.64 years. Three clusters were identified and classified as High, Medium and Low sense of Coherence. When establishing the relationship with HbA1c it was found that the High Group had an average HbA1c of 6.22%, the middle group 7.24% and the low group 7.49% of HbA1c, p <. 05. It was identified that a high Sense of Coherence is significantly associated to a better metabolic control given by HB A1c.

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Comparing the Arrangements of Governance and Sustainable Development in OECD Countries: Coupled or Decoupled?

Korean Journal of Policy Studies ◽

10.52372/kjps34105 ◽

2019 ◽

Vol 34 (1) ◽

pp. 99-117

Author(s):

Huh Taewook

Keyword(s):

Sustainable Development ◽

Oecd Countries ◽

The Other ◽

Type Analysis ◽

Ideal Types ◽

Type 3 ◽

Relationship Of ◽

The Relationship

This study attempts to analyze to what extent governance and sustainable development (SD) empirically appear compatible in the thirtyfive OECD countries through the fuzzy-set ideal type analysis, and identify which ideal types appear coupled or decoupled, and then reveal which countries belong to the coupled types or to the decoupled types. In short, twenty-two countries (including Sweden (fuzzy score, 0.953), Denmark (0.920), Finland (0.914), Norway (0.911) in Type 1 (G*S, ‘strong G-S coupled countries’); and Turkey (0.906), Greece (0.833), Mexico (0.828) in Type 4 (g*s, ‘lite g-s coupled countries’) are in line with the accepted conventions regarding the compatible relationship between governance and SD. On the other hand, the rest of thirteen countries (including USA (fuzzy score, 0.815), Luxembourg (0.721), Australia (0.660) in Type 2 (G*s, ‘G-s decoupled countries’); and Slovenia (0.728), France (0.644), Czech Rep. (0.625) in Type 3 (g*S, ‘g-S decoupled countries’) may indicate that the relationship of governance and SD is in fact experiencing tensions in the national contexts. These findings are characterized by the substance (of SD) and procedure (of governance) divide. Considering the results, this study focuses on the idea of reflexivity or reflexive capacity.

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Genetic Polymorphisms of Antioxidant and Antiglycation Enzymes and Diabetic Complications. How Much Can we Learn from the Genes?

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-0043-106442 ◽

2017 ◽

Vol 126 (01) ◽

pp. 7-13

Author(s):

Dimitrios Oikonomou ◽

Jan Benedikt Groener ◽

Ruan Cheko ◽

Zoltan Kender ◽

Lars Kihm ◽

...

Keyword(s):

Diabetic Complications ◽

Diabetes Mellitus Type 1 ◽

Diabetic Complication ◽

Clinical Use ◽

Oxygen Species ◽

Patients With Diabetes ◽

Genetically Determined ◽

Novel Therapeutic

AbstractThere is growing evidence that reactive metabolites, such as reactive oxygen species and dicarbonyls contribute to diabetic complications. Formation, accumulation, and detoxification of these metabolites are controlled by several enzymes, some of which have genetically determined levels of expression or function. This review not only gives an overview of the different SNPs studied in patients with diabetes mellitus type 1 and type 2, but in addition attempts to bridge the gap between a genetic study and clinical use. Therefore, not only the results of the studies are reviewed, but also their use in identification of subgroups where an increased or decreased risk for a diabetic complication is described, as well as their use in developing novel therapeutic options based on understanding the contribution of an enzyme to a given complication.

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