Ramelteon for the Treatment of Delirium in Elderly Patients: A Consecutive Case Series Study

2014 ◽  
Vol 47 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Akihiro Tsuda ◽  
Katsuji Nishimura ◽  
Eiko Naganawa ◽  
Tempei Otsubo ◽  
Jun Ishigooka
Keyword(s):  
Elderly Patients ◽  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study

Patterns of Fundus Autofluorescence in Eyes with Myopic Atrophy Maculopathy: A Consecutive Case Series Study

2020 ◽  
pp. 1-5
Author(s):  
Jun Li ◽  
Xiujuan Zhao ◽  
Shida Chen ◽  
Bingqian Liu ◽  
Yonghao Li ◽  
...  
Keyword(s):  
Fundus Autofluorescence ◽  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study

scholarly journals Evidence for Dietary Agmatine Sulfate Effectiveness in Neuropathies Associated with Painful Small Fiber Neuropathy. A Pilot Open-Label Consecutive Case Series Study

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 576 ◽  
Author(s):  
Michael L. Rosenberg ◽  
Vahid Tohidi ◽  
Karna Sherwood ◽  
Sujoy Gayen ◽  
Rosina Medel ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Pain Intensity ◽  
Treatment Options ◽  
Case Series ◽  
Small Fiber Neuropathy ◽  
Consecutive Case ◽  
Open Label ◽  
Small Fiber ◽  
Case Series Study ◽  
Series Study

Peripheral neuropathies associated with painful small fiber neuropathy (SFN) are complex conditions, resistant to treatment with conventional medications. Previous clinical studies strongly support the use of dietary agmatine as a safe and effective treatment for neuropathic pain. Based on this evidence, we conducted an open-label consecutive case series study to evaluate the effectiveness of agmatine in neuropathies associated with painful SFN (Study Registry: ClinicalTrials.gov, System Identifier: NCT01524666). Participants diagnosed with painful SFN and autonomic dysfunctions were treated with 2.67 g/day agmatine sulfate (AgmaSet® capsules containing G-Agmatine® brand of agmatine sulfate) for a period of 2 months. Before the beginning (baseline) and at the end of the treatment period, participants answered the established 12-item neuropathic pain questionnaire specifically developed to distinguish symptoms associated with neuropathy and to quantify their severity. Secondary outcomes included other treatment options and a safety assessment. Twelve patients were recruited, and 11 patients—8 diagnosed with diabetic neuropathy, two with idiopathic neuropathy and one with inflammatory neuropathy—completed the study. All patients showed improvement in neuropathic pain to a varied extent. The average decrease in pain intensity was 26.0 rating points, corresponding to a 46.4% reduction in overall pain (p < 0.00001). The results suggest that dietary agmatine sulfate has a significant effect in reducing neuropathic pain intensity associated with painful SFN resistant to treatment with conventional neuropathic pain medications. Larger randomized placebo-controlled studies are expected to establish agmatine sulfate as a preferred treatment.

scholarly journals SARS‐CoV‐2 tracheitis in laryngectomised patients: A consecutive case‐series study

2021 ◽  
Author(s):  
Ignacio Javier Fernandez ◽  
Federico Spagnolo ◽  
Sara Valerini ◽  
Francesco Mattioli ◽  
Gabriele Molteni ◽  
...  
Keyword(s):  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study

scholarly journals SARS-CoV-2 tracheitis in laryngectomized patients: a consecutive case-series study.

2021 ◽  
Author(s):  
Ignacio Fernandez ◽  
Federico Spagnolo ◽  
Sara Valerini ◽  
Francesco Mattioli ◽  
Alessandro Marchioni ◽  
...  
Keyword(s):  
Lung Function ◽  
Clinical Picture ◽  
Case Series ◽  
Respiratory Epithelium ◽  
Consecutive Case ◽  
Airway Complications ◽  
Case Series Study ◽  
Key Points ◽  
Series Study ◽  
Possible Cause

Key points • SARS-CoV-2 is a possible cause of acute severe tracheitis in laryngectomees. • In our series, the clinical picture was characterized by a hemorrhagic tracheitis with a slow resolution pattern. • We observed a histological pattern of erosive inflammation of the respiratory epithelium. • Planned tracheo-bronchoscopy and tracheal toilettes are recommended to prevent critical obstruction of the airway, which can be fatal in patients with associated impairment of lung function caused by SARS-CoV-2 infection. • The present cases highlight the need for close interdisciplinary working and communication in the management of airway complications of COVID-19 infection.

scholarly journals The Use of Sentinel Lymph Node Biopsy in BRCA1/2 Mutation Carriers Undergoing Prophylactic Mastectomy: A Retrospective Consecutive Case-Series Study

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Sara Câmara ◽  
Daniela Pereira ◽  
Saudade André ◽  
Beatriz Mira ◽  
Fátima Vaz ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Prophylactic Mastectomy ◽  
Case Series ◽  
Lymph Node Biopsy ◽  
Consecutive Case ◽  
Node Biopsy ◽  
Case Series Study ◽  
Series Study

Introduction. Sentinel lymph node biopsy in prophylactic mastectomy is controversial. It avoids lymphadenectomy in occult carcinoma but is associated with increased morbidity. Women with BRCA mutations have a higher incidence of occult carcinoma and our objective was to assess the clinical utility of sentinel lymph node biopsy when these women undergo prophylactic mastectomy. Materials and Methods. Seven-year retrospective consecutive case-series study of women, with a BRCA deleterious mutation, admitted to prophylactic mastectomy, at our center. Breast MRI < 6 months before surgery was routine, unless contraindicated. Results. Fifty-seven patients (43% BRCA1; 57% BRCA2) underwent 80 prophylactic mastectomies. 72% of patients had had breast cancer treated before prophylactic mastectomy or synchronously to it. The occult carcinoma incidence was 5%, and half of the cases were invasive. SLNB was performed in 19% of the prophylactic mastectomies; none of these had tumor invasion. Women with invasive carcinoma who had not undergone sentinel lymph node biopsy were followed closely with axillary ultrasound. The median follow-up was 37 months, with no local recurrence; 1 patient died of primary tumor systemic relapse. Conclusions. Our data do not support this procedure for routine (in agreement with previous literature), in this high risk for occult carcinoma population.

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