scholarly journals SARS-CoV-2 tracheitis in laryngectomized patients: a consecutive case-series study.

2021 ◽  
Author(s):  
Ignacio Fernandez ◽  
Federico Spagnolo ◽  
Sara Valerini ◽  
Francesco Mattioli ◽  
Alessandro Marchioni ◽  
...  
Keyword(s):  
Lung Function ◽  
Clinical Picture ◽  
Case Series ◽  
Respiratory Epithelium ◽  
Consecutive Case ◽  
Airway Complications ◽  
Case Series Study ◽  
Key Points ◽  
Series Study ◽  
Possible Cause

Key points • SARS-CoV-2 is a possible cause of acute severe tracheitis in laryngectomees. • In our series, the clinical picture was characterized by a hemorrhagic tracheitis with a slow resolution pattern. • We observed a histological pattern of erosive inflammation of the respiratory epithelium. • Planned tracheo-bronchoscopy and tracheal toilettes are recommended to prevent critical obstruction of the airway, which can be fatal in patients with associated impairment of lung function caused by SARS-CoV-2 infection. • The present cases highlight the need for close interdisciplinary working and communication in the management of airway complications of COVID-19 infection.

Patterns of Fundus Autofluorescence in Eyes with Myopic Atrophy Maculopathy: A Consecutive Case Series Study

2020 ◽  
pp. 1-5
Author(s):  
Jun Li ◽  
Xiujuan Zhao ◽  
Shida Chen ◽  
Bingqian Liu ◽  
Yonghao Li ◽  
...  
Keyword(s):  
Fundus Autofluorescence ◽  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study

scholarly journals Evidence for Dietary Agmatine Sulfate Effectiveness in Neuropathies Associated with Painful Small Fiber Neuropathy. A Pilot Open-Label Consecutive Case Series Study

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 576 ◽  
Author(s):  
Michael L. Rosenberg ◽  
Vahid Tohidi ◽  
Karna Sherwood ◽  
Sujoy Gayen ◽  
Rosina Medel ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Pain Intensity ◽  
Treatment Options ◽  
Case Series ◽  
Small Fiber Neuropathy ◽  
Consecutive Case ◽  
Open Label ◽  
Small Fiber ◽  
Case Series Study ◽  
Series Study

Peripheral neuropathies associated with painful small fiber neuropathy (SFN) are complex conditions, resistant to treatment with conventional medications. Previous clinical studies strongly support the use of dietary agmatine as a safe and effective treatment for neuropathic pain. Based on this evidence, we conducted an open-label consecutive case series study to evaluate the effectiveness of agmatine in neuropathies associated with painful SFN (Study Registry: ClinicalTrials.gov, System Identifier: NCT01524666). Participants diagnosed with painful SFN and autonomic dysfunctions were treated with 2.67 g/day agmatine sulfate (AgmaSet® capsules containing G-Agmatine® brand of agmatine sulfate) for a period of 2 months. Before the beginning (baseline) and at the end of the treatment period, participants answered the established 12-item neuropathic pain questionnaire specifically developed to distinguish symptoms associated with neuropathy and to quantify their severity. Secondary outcomes included other treatment options and a safety assessment. Twelve patients were recruited, and 11 patients—8 diagnosed with diabetic neuropathy, two with idiopathic neuropathy and one with inflammatory neuropathy—completed the study. All patients showed improvement in neuropathic pain to a varied extent. The average decrease in pain intensity was 26.0 rating points, corresponding to a 46.4% reduction in overall pain (p < 0.00001). The results suggest that dietary agmatine sulfate has a significant effect in reducing neuropathic pain intensity associated with painful SFN resistant to treatment with conventional neuropathic pain medications. Larger randomized placebo-controlled studies are expected to establish agmatine sulfate as a preferred treatment.

scholarly journals SARS‐CoV‐2 tracheitis in laryngectomised patients: A consecutive case‐series study

2021 ◽  
Author(s):  
Ignacio Javier Fernandez ◽  
Federico Spagnolo ◽  
Sara Valerini ◽  
Francesco Mattioli ◽  
Gabriele Molteni ◽  
...  
Keyword(s):  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study

scholarly journals Analysis of Homeopathic Genus Epidemicus for COVID-19 Patients in Spain

Homeopathy ◽  
2021 ◽  
Author(s):  
Marc Lluís Clapers ◽  
Manuela Velat ◽  
Josep Maria Clapers ◽  
Joan Vidal-Jové ◽  
Joan Mora
Keyword(s):  
Clinical Picture ◽  
Close Contact ◽  
Case Series ◽  
Case Analysis ◽  
Full Recovery ◽  
Case Series Study ◽  
Prescribed Medicines ◽  
Prospective Case Series ◽  
Series Study

Abstract Background Homeopathy has had documented success treating epidemics in the last two centuries. We aimed to obtain a clear homeopathic clinical picture of coronavirus disease 2019 (COVID-19) and postulate the genus epidemicus of the disease in order to inform and enhance future treatment and prophylaxis options. Methods We conducted a prospective case series study, collecting data from 19 homeopaths in Catalonia, Spain, from patients who presented with fever and/or cough and/or breathlessness and/or confirmed COVID-19 infection or close contact with a confirmed case. We included 107 patients, and data were recorded through a checklist questionnaire on the day of the case analysis and at day 10–15 after commencing treatment. Symptoms were collected and analyzed with the help of homeopathic repertories. Results A total of 103 cases were mild or moderate; four were severe. The severe cases were excluded from the analysis and the 103 mild and moderate cases were analyzed and a clear overall clinical picture with mental, general, and particular symptoms was achieved. Eighty-eight cases had a complete recorded follow-up. The most prescribed medicines were Bry, Ars, Phos and Gels, whilst those with the best rates of good response were Sulph, Puls and Bry. Time to full recovery after homeopathic treatment ranged from 3.5 to 14.4 days, depending on the medicine used. The potency 200c was associated with faster rates of full recovery and a lesser need to change remedy. Conclusion We have defined the symptomatic homeopathic characteristics of mild and moderate COVID-19 in Spain and established a set of medicines that might be useful to consider as effective genus epidemicus.

Ramelteon for the Treatment of Delirium in Elderly Patients: A Consecutive Case Series Study

2014 ◽  
Vol 47 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Akihiro Tsuda ◽  
Katsuji Nishimura ◽  
Eiko Naganawa ◽  
Tempei Otsubo ◽  
Jun Ishigooka
Keyword(s):  
Elderly Patients ◽  
Case Series ◽  
Consecutive Case ◽  
Case Series Study ◽  
Series Study
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