Mobile health (mhealth) interventions for treatment adherence and outcomes of care for cardio-metabolic disease among adults living with HIV: A systematic review (Preprint)
BACKGROUND The success of antiretroviral therapy (ART) has led to an increase in the risk of cardio-metabolic diseases (CMD) among people living with HIV (PLHIV). OBJECTIVE To examine the patterns of use of mobile health (mhealth) interventions to improve treatment adherence or outcomes of care of CMD among PLHIV. METHODS Studies were included if they had at least one component that used a mobile intervention to address treatment adherence and/or one or more of the stated outcomes of care for CMD among PLHIV RESULTS Ten studies were included in the review, four of which had published results. The remaining six were articles that described mhealth interventions for PLHIV. The categories of mhealth interventions ranged from short messaging, telephone calls and wearable devices to smartphone and desktop web-based mobile applications, with short messaging and telephone calls being the most common. Several of the outcomes in this review were only indirectly linked to CMD, with most studies reporting the effectiveness of the interventions CONCLUSIONS Due to the limited number of published studies, no definitive conclusions can be made on the effectiveness of mhealth interventions for adherence support in PLHIV with CMD CLINICALTRIAL The study protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) CRD86940 (http://www.crd.york.ac.uk/prospero).