Original and refitted HOSPITAL scores as predictors of 30-day potentially avoidable hospital readmissions: retrospective cohort study (Preprint)

2020 ◽  
Author(s):  
Nayara Cristina Da Silva ◽  
Marcelo Keese Albertini ◽  
André Ricardo Backes ◽  
Geórgia Das Graças Pena

BACKGROUND Hospital readmissions are associated with several negative health outcomes and higher hospital costs. The HOSPITAL score is one of the tools developed to identify patients at high risk of hospital readmission, but its predictive capacity in more heterogeneous populations involving different diagnoses and clinical contexts is poorly understood. OBJECTIVE The aim of this study was to propose a refitted HOSPITAL score to predict the risk of potentially avoidable readmission in 30 days and compare the predictive capacity of the original and refitted HOSPITAL score. METHODS Retrospective cohort study was carried out in a tertiary university hospital with patients over the age of 18 years. We developed a refitted HOSPITAL score with the same definitions and predictive variables included in the original HOSPITAL score and compared the predictive capacity of both. The receiver operating characteristic was constructed by comparing the performance risk forecasting tools measuring the area under the curve (AUC). RESULTS Of the 47,464 patients 50.9% were over 60 years and 58.4% were male. The frequency of 30-day potentially avoidable readmission is 7.70% (3638). The accuracy of HOSPITAL score in readmission was AUC: 0.733 (CI 95%: 0.718, 0.748) and the accuracy of HOSPITAL score refitted was AUC: 0.7401 (CI 95%: 0.7256, 0.7547). The frequency of 60, 90, 180, and 365-days readmissions ranged from 10.60% (5,033) to 18.30% (8693). Discussion: Readmission prediction tools have been developed in recent years, but its predictive capacity in more population with different diagnoses is poorly understood. CONCLUSIONS The refitted HOSPITAL score have similar discrimination to predict 30-day potentially avoidable readmission, in patients with different diagnoses. In this sense, our study expands and reinforces the usefulness of the HOSPITAL score as a tool that can be used as part of intervention strategies to reduce the rate of hospital readmission.

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e033551 ◽  
Author(s):  
Efi Mantzourani ◽  
Hamde Nazar ◽  
Catherine Phibben ◽  
Jessica Pang ◽  
Gareth John ◽  
...  

ObjectiveTo evaluate the association of the discharge medicines review (DMR) community pharmacy service with hospital readmissions through linking National Health Service data sets.DesignRetrospective cohort study.SettingAll hospitals and 703 community pharmacies across Wales.ParticipantsInpatients meeting the referral criteria for a community pharmacy DMR.InterventionsInformation related to the patient’s medication and hospital stay is provided to the community pharmacists on discharge from hospital, who undertake a two-part service involving medicines reconciliation and a medicine use review. To investigate the association of this DMR service with hospital readmission, a data linking process was undertaken across six national databases.Primary outcomeRate of hospital readmission within 90 days for patients with and without a DMR part 1 started.Secondary outcomeStrength of association of age decile, sex, deprivation decile, diagnostic grouping and DMR type (started or not started) with reduction in readmission within 90 days.Results1923 patients were referred for a DMR over a 13-month period (February 2017–April 2018). Provision of DMR was found to be the most significant attributing factor to reducing likelihood of 90-day readmission using χ2 testing and classification methods. Cox regression survival analysis demonstrated that those receiving the intervention had a lower hospital readmission rate at 40 days (p<0.000, HR: 0.59739, CI 0.5043 to 0.7076).ConclusionsDMR after a hospital discharge is associated with a reduction in risk of hospital readmission within 40 days. Linking data across disparate national data records is feasible but requires a complex processual architecture. There is a significant value for integrated informatics to improve continuity and coherency of care, and also to facilitate service optimisation, evaluation and evidenced-based practice.


2017 ◽  
Vol 56 (10) ◽  
pp. 1265-1271 ◽  
Author(s):  
Liisa K. Rautakorpi ◽  
Johanna M. Mäkelä ◽  
Fatemeh Seyednasrollah ◽  
Anna M. Hammais ◽  
Tarja Laitinen ◽  
...  

Author(s):  
Sumyia Mehrin M. D. Abulkalam ◽  
Mai Kadi ◽  
Mahmoud A. Gaddoury ◽  
Wallaa Khalid Albishi

Background: The association between tuberculosis (TB) and diabetes mellitus (DM) is re-emerging with the epidemic of type II diabetes. Both TB and DM were of the top 10 causes of death.[1] This study explores diabetes mellitus as a risk factor for developing the different antitubercular drug-resistant (DR) patterns among TB patients.  Methods: A retrospective cohort study has been conducted on all TB cases reported to the King Abdul Aziz University Hospital, Jeddah, between January 2012 to January 2021. All culture-confirmed and PCR-positive TB cases were included in this study. Categorical baseline characteristic of TB patient has been compared with DM status by using Fisher's exact and Pearson chi-square test. The univariable and multivariable logistic regression model was used to estimate the association between DM and different drug resistance patterns.  Results: Of the total 695 diagnosed TB patients, 92 (13.24%) are resistant to 1st line anti TB drugs. Among 92 DR-TB patients, 36 (39.13%) are diabetic. The percentage of different patterns of DR-TB with DM, in the case of mono DR (12.09%), poly DR (4.19%) MDR (0.547%). As a risk factor, DM has a significant association with DR-TB, mono drug-resistant, and pyrazinamide-resistant TB (P-value <0.05). The MDR and PDR separately do not show any significant association with DM, but for further analysis, it shows a significant association with DM when we combined.  Conclusion: Our study identified diabetes mellitus as a risk factor for developing DR-TB. Better management of DM and TB infection caring programs among DM patients might improve TB control and prevent DR-TB development in KSA.


2018 ◽  
Vol 46 (6) ◽  
pp. 579-585 ◽  
Author(s):  
Nina Kimmich ◽  
Jana Juhasova ◽  
Christian Haslinger ◽  
Nicole Ochsenbein-Kölble ◽  
Roland Zimmermann

Abstract Aim: To assess fetal descent rates of nulliparous and multiparous women in the active phase of labor and to evaluate significant impact factors. Methods: In a retrospective cohort study at the University Hospital of Zurich, Switzerland, we evaluated 6045 spontaneous vaginal deliveries with a singleton in vertex presentation between January 2007 and July 2014 at 34 0/7 to 42 0/7 gestational weeks. Median fetal descent rates and their 10th and 90th percentiles were assessed in the active phase of labor and different impact factors were evaluated. Results: Fetal descent rates are exponentially increasing. Nulliparous women have slower fetal descent than multiparous women (P<0.001), ranging from 0 to 5.81 cm/h and from 0 to 15 cm/h, respectively. The total duration of fetal descent in labor is 5.42 h for nulliparous and 2.71 h for multiparous women. Accelerating impact factors are a lower fetal station, multiparity, increasing maternal weight and fetal occipitoanterior position, whereas epidural anesthesia decelerates fetal descent (P<0.001). Conclusions: Fetal descent is a hyperbolic increasing process with faster descent in multiparous women compared to nulliparous women, is highly inter individual and is associated with different impact factors. The diagnosis of labor arrest or prolonged labor should therefore be based on such rates as well as on individual evaluation of every parturient.


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