Mathematical myocardium elasticity properties modeling in echocardiography study of diastolic and systolic function of the left ventricle

2018 ◽  
Author(s):  
Lucian Popescu ◽  
Adina Ligia Pop-Moldovan ◽  
Nelu-Mihai Trofenciuc ◽  
Maria Puschita
Keyword(s):  
Left Ventricle ◽  
Systolic Function

743 Left ventricular long-axis function during dobutamine infusion in patients with impaired systolic function of the left ventricle

2003 ◽  
Vol 2 (1) ◽  
pp. 158-159
Author(s):  
K BOUKI ◽  
T KAKAVAS ◽  
K KOSTOPOULOS ◽  
A KOTSAKIS ◽  
K POULOPOULOS ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Systolic Function ◽  
Left Ventricular ◽  
Dobutamine Infusion

Mathematical myocardium elasticity properties modeling in echocardiography study of diastolic and systolic function of the left ventricle (Preprint)

2020 ◽  
Author(s):  
Lucian Popescu ◽  
Nelu-Mihai Trofenciuc ◽  
Simina Crisan ◽  
Aurora Diana Bordejevic ◽  
Alexandru Mischie ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Cardiac Cycle ◽  
Systolic Function ◽  
Study Group ◽  
Mathematical Approach ◽  
Energetic Approach ◽  
Elasticity Property ◽  
Property Modeling ◽  
Coefficient Of Elasticity ◽  
Mechanical Movement

BACKGROUND A systematic and quantitative comparative analysis for this subject has not been done so far. Thus defined, the coefficient of elasticity is a whole new dimension. OBJECTIVE This study proposes a new mathematical myocardium elasticity property modeling in characterizing of the ventricular diastole and systole. METHODS The study group consisted of 2283 consecutive patients evaluated by echocardiography. The mathematical approach is made starting from energetic consideration, by applying the energy conservation low for the blood entering from left atrium into left ventricle during diastole period. RESULTS Analyzing all the data obtained we developed two brand new coefficients to describe the cardiac cycle and we had verified if the coefficients are correlated with classically used parameters. We consider that the energetic approach take into consideration the whole mechanical movement that is happening inside the heart and can offer a very synthetic and scientific solid view about the cardiac cycle. CONCLUSIONS The new coefficients are simply to be calculated and as you will see from our research the correlation with other classically used parameters is obvious. The direct physical approach of blood flow within the heart can generate new, beneficial perspectives in diagnosing various heart conditions, or even in understanding how works the filling of the ventricles and atria during a heartbeat.

scholarly journals Myocardial deformation in patients with a single left ventricle using 2D cardiovascular magnetic resonance feature tracking: a case–control study

2021 ◽  
Author(s):  
Fabian Strodka ◽  
Jana Logoteta ◽  
Roman Schuwerk ◽  
Mona Salehi Ravesh ◽  
Dominik Daniel Gabbert ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricle ◽  
Feature Tracking ◽  
Systolic Function ◽  
Radial Strain ◽  
Left Ventricular ◽  
Lv Function ◽  
Significant Difference ◽  
Lv Volumes

AbstractVentricular dysfunction is a well-known complication in single ventricle patients in Fontan circulation. As studies exclusively examining patients with a single left ventricle (SLV) are sparse, we assessed left ventricular (LV) function in SLV patients by using 2D-cardiovascular magnetic resonance (CMR) feature tracking (2D-CMR-FT) and 2D-speckle tracking echocardiography (2D-STE). 54 SLV patients (11.4, 3.1–38.1 years) and 35 age-matched controls (12.3, 6.3–25.8 years) were included. LV global longitudinal, circumferential and radial strain (GLS, GCS, GRS) and strain rate (GLSR, GCSR, GRSR) were measured using 2D-CMR-FT. LV volumes, ejection fraction (LVEF) and mass were determined from short axis images. 2D-STE was applied in patients to measure peak systolic GLS and GLSR. In a subgroup analysis, we compared double inlet left ventricle (DILV) with tricuspid atresia (TA) patients. The population consisted of 19 DILV patients, 24 TA patients and 11 patients with diverse diagnoses. 52 patients were in NYHA class I and 2 patients were in class II. Most SLV patients had a normal systolic function but median LVEF in patients was lower compared to controls (55.6% vs. 61.2%, p = 0.0001). 2D-CMR-FT demonstrated reduced GLS, GCS and GCSR values in patients compared to controls. LVEF correlated with GS values in patients (p < 0.05). There was no significant difference between GLS values from 2D-CMR-FT and 2D-STE in the patient group. LVEF, LV volumes, GS and GSR (from 2D-CMR-FT) were not significantly different between DILV and TA patients. Although most SLV patients had a preserved EF derived by CMR, our results suggest that, LV deformation and function may behave differently in SLV patients compared to healthy subjects.

Computational Modeling of Human Left Ventricle to Assess the Effects of Trabeculae Carneae on the Diastolic and Systolic Functions

2019 ◽  
Vol 141 (9) ◽  
Author(s):  
Fatemeh Fatemifar ◽  
Marc D. Feldman ◽  
Geoffrey D. Clarke ◽  
Ender A. Finol ◽  
Hai-Chao Han
Keyword(s):  
Left Ventricle ◽  
Systolic Function ◽  
Strain Energy Function ◽  
Patient Specific ◽  
Papillary Muscles ◽  
End Diastolic Volume ◽  
Wall Stiffness ◽  
Biaxial Tests ◽  
Cutting Model

Trabeculae carneae are irregular structures that cover the endocardial surfaces of both ventricles and account for a significant portion of human ventricular mass. The role of trabeculae carneae in diastolic and systolic functions of the left ventricle (LV) is not well understood. Thus, the objective of this study was to investigate the functional role of trabeculae carneae in the LV. Finite element (FE) analyses of ventricular functions were conducted for three different models of human LV derived from high-resolution magnetic resonance imaging (MRI). The first model comprised trabeculae carneae and papillary muscles, while the second model had papillary muscles and partial trabeculae carneae, and the third model had a smooth endocardial surface. We customized these patient-specific models with myofiber architecture generated with a rule-based algorithm, diastolic material parameters of Fung strain energy function derived from biaxial tests and adjusted with the empirical Klotz relationship, and myocardial contractility constants optimized for average normal ejection fraction (EF) of the human LV. Results showed that the partial trabeculae cutting model had enlarged end-diastolic volume (EDV), reduced wall stiffness, and even increased end-systolic function, indicating that the absence of trabeculae carneae increased the compliance of the LV during diastole, while maintaining systolic function.

P2639The influence of non-dipping pattern of blood pressure in gestational hypertension on early onset of hypertension later in life

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Ilic ◽  
S Stojsic ◽  
J Papovic ◽  
D Grkovic ◽  
T Miljkovic ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Regression Analysis ◽  
Left Ventricle ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Gestational Hypertension ◽  
Systolic Function ◽  
Blood Pressure Monitoring ◽  
Night Time ◽  
Lv Mass

Abstract Background It is known that gestational hypertension (GH) and preeclampsia have been associated with the onset of hypertension later in life. We wondered if the blood pressure (BP) pattern affects the incidence of hypertension in the future. Purpose The aim of this study was to determine whether hypertension occurs more frequently if a non-dipping pattern was registered during GH, but also if non-dipping pattern in GH afects deterioration of systolic function of the left ventricle (LV) later in life. Methods This longitudinal study included 56 pregnant women with gestational hypertension (of which 28 met criteria for non-dipping pattern of BP, according to the values registrated by the ambulatory blood pressure monitoring (ABPM) – non-dippers, while other 28 were classified in dippers) and 27 normotensive pregnant women, as control. All of women became normotensive after delivery, but they continued to be periodically controlled in term of values of blood pressure. The function and morphology of the left ventricle (LV) were analyzed by echocardiography exam in the third trimester of pregnancy and 5 years after delivery, as well as ABPM, while 2D longitudinal strain (LS) was performed only after delivery in order to evaluate systolic function of the LV. All echo and ABPM parameters recorded during pregnancy, also as parameters of pregnancy outcome – intrauterine growth restriction (IUGR) and preterm delivery, were analyzed, in order to relate them with later onset of hypertension. Results After, average 5 years, diagnosis of hypertension was determined in 8 women (2 from dipper group – during pregnancy – 7,1%, and 6 from non-dipper group 21,4%). Those 8 hypertensive women had significantly reduced LS: −18,12±1,3 compared to normotensive −19,9±1,4 (p=0,001). It is very interesting that, 5 years after delivery, values of 2D LS were, although in reference values, significantly reduced in women who were non-dippers (−19,32±1,38) during GH, compared with both, normotensive (−20,69±1,18; p<0,0005) and dippers (−20,10±1,29; p=0,026). Univariate regression analysis revealed that higher values of day and night BP, the mean arterial BP, LV mass index, preterm delivery and IUGR were associated with onset of hypertension later in life, while parameters of systolic and diastolic function of the LV during pregnancy, didn't affect occurrence of it. As revealed by multivariate regression analysis, the peak value of night-time diastolic blood pressure during pregnancy (p=0,016; OR=1,127; 95% CI: 1,022–1,242) and the LV mass index, also during pregnancy (p=0,041; OR=1,099; 95% CI: 1,004–1,203) had strong relation with hypertension in future life. Conclusion The non-dipping pattern of blood pressure in gestationl hypertension is significant associate with onset of hypertension later in life, but also with decreased systolic function of the left ventricle. Acknowledgement/Funding Provincial Secretariat for Health of the Autonomous Province of Vojvodina

scholarly journals Unexpected normal left ventricular systolic function after total chronic occlusion of left main coronary artery and stenosis of right coronary artery: a case report and review of the literature

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Younes Moutakiallah ◽  
Reda Mounir ◽  
Amir Aden Ali ◽  
Fouad Nya ◽  
Aniss Seghrouchni ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Left Ventricle ◽  
Right Coronary Artery ◽  
Left Main Coronary Artery ◽  
Systolic Function ◽  
Artery Bypass ◽  
Left Main ◽  
Total Occlusion ◽  
Chronic Occlusion ◽  
The Impact

Abstract Introduction Total occlusion of the left main coronary artery is a very rare finding in coronary angiography because of its highly lethal nature. Right coronary artery dominance and extensive collateral circulation are the principal determinant factors of survival after total occlusion of the left main coronary artery. The impact on the left ventricle is often significant with a profound alteration of its systolic function. Case presentation We describe a 52-year-old North African man, a tobacco smoker, who presented symptoms of unstable angina related to a total chronic occlusion of his left main coronary artery with a right coronary artery stenosis. Unexpectedly, the impact on his left ventricle was absent with normal dimensions and systolic function. He underwent a successful on-pump coronary artery bypass grafting with uneventful postoperative course and good recovery. Conclusions Total occlusion of the left main coronary artery is a rare condition, the fact that the left ventricle retains a normal size and systolic function makes it exceptional, which must be kept in mind to avoid dangerous examinations and delayed treatment. Coronary artery bypass surgery should be considered the main treatment of total chronic occlusion of the left main coronary artery.

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