Can Adrenal Adenomas Be Differentiated From Adrenal Metastases at Single-Phase Contrast-Enhanced CT?

2018 ◽  
Vol 211 (5) ◽  
pp. 1044-1050 ◽  
Author(s):  
Wendy Tu ◽  
Raman Verma ◽  
Satheesh Krishna ◽  
Matthew D. F. McInnes ◽  
Trevor A. Flood ◽  
...  
2020 ◽  
Vol 93 (1106) ◽  
pp. 20190735
Author(s):  
Basak Gulpinar ◽  
Elif Peker ◽  
Cigdem Soydal ◽  
Mine Araz ◽  
Atilla Halil Elhan

Objective: To assess the usefulness of a single-phase contrast-enhanced CT to differentiate subtypes of neuroendocrine tumour (NET) liver metastases and to evaluate the correlation between CT features and Ga-68 DOTATATE positron emission tomography/CT (PET/CT) findings. Methods: Between December 2017 and April 2019 patients with liver metastases of neuroendocrine tumours who underwent CT and Ga-68 DOTATATE PET/CT were enrolled in the study. All patients involved in the study had undergone a standardised single-phase contrast-enhanced CT. Whole body PET/CT images were obtained with a combined PET/CT scanner. All CT images were retrospectively analysed by two radiologists. Enhancement patterns of lesions were assessed. For quantitative examination; CT attenuation values of metastatic lesions, liver parenchyma and aorta were measured using a freehand ROI and tumour-to-liver ratio [T–L = (Tumour–Liver) / Liver] and tumour-to-aorta ratio [T–A = (Tumour–Aorta) / Aorta] were calculated. The lesion with the highest Ga-68 DOTATATE uptake in the liver was used for calculations. The metabolic tumour volume (MTV), maximum standardised uptake value (SUV max) and SUV mean were calculated for the target liver lesion. Results: A total of 137 NET liver metastases divided into in three groups: 49 (35.7%) pancreatic, 60 (44.5%) gastroenteric and 26 (18.9%) lung NET liver metastases were analysed. Gastroenteric NET metastases often showed heterogeneous enhancement which was significantly higher than in the pancreas and lung NET liver metastases (p < 0.001). 96.72% (n = 59) of the gastroenteric NET liver metastases were hypoattenuating whereas the most frequent presentation for the pancreatic group was hyperattenuation (63.26%,n = 31). The difference in enhancement patterns of the liver metastases was statistically significant (p < 0.001) with respect to the location of the primary tumour. For quantitative analysis; tumour CT values were significantly different between the groups (p < 0.001). The T–L ratio was statistically different between gastroenteric and pancreatic NET liver metastases and pancreatic and lung NET groups (p < 0.001). The T–A ratio was significantly higher in the pancreatic NET metastases (p < 0.001). SUVmax, SUVmean and MTV values, however, were not significantly different between the subgroups. There was a weak positive correlation between T–L ratio and SUV meanvalues. Conclusion: We noticed statistically significant differences in both qualitative and quantitative CT features between histologic subgroups of neuroendocrine tumour liver metastases at a single phase contrast-enhanced CT. Advances in knowledge: Our study will be the first in the literature which extensively focus on assessing the CT features of liver metastases of NETs at a single phase CT and Ga-68DOTATATE PET/CT. As the different histological subtypes of NET liver metastases exhibit different clinical outcomes, these features might help to identify the primary tumour to provide optimal treatment.


2013 ◽  
Vol 26 (6) ◽  
pp. 1082-1090 ◽  
Author(s):  
Matthias Hammon ◽  
Alexander Cavallaro ◽  
Marius Erdt ◽  
Peter Dankerl ◽  
Matthias Kirschner ◽  
...  

Author(s):  
Yuji Nishimoto ◽  
Masanao Toma ◽  
Kohei Iwasa ◽  
Yukihito Sato

Abstract Background Spontaneous iliac vein ruptures have only been reported in approximately 50 cases. An accurate preoperative diagnosis is difficult even with contrast-enhanced computed tomography (CT), and the operative mortality and morbidity rates are quite high. The cause of spontaneous iliac vein ruptures and their optimal diagnosis and management remain unclear. Case Summary A 69-year-old woman without a history of prior trauma presented with low back pain, left lower limb swelling, and hypovolemic shock. An initial contrast-enhanced CT revealed a large retroperitoneal hematoma without arterial extravasation. Her blood pressure dropped again under a noradrenaline administration. A second venous phase contrast-enhanced CT revealed venous extravasation in the external iliac vein with a suspected compression of the common iliac vein (May-Thurner syndrome) and deep vein thrombosis (DVT). Her haemodynamics were stabilised whilst a laparotomy was arranged. An inferior vena cava (IVC) filter was placed due to concerns about rebleeding with initiating anticoagulation therapy. Given the failed conservative management, elective endovascular treatment (EVT) was performed including percutaneous Fogarty venous thrombectomy and placement of self-expanding and covered stents. After the intervention, the lower limb swelling significantly improved under oral anticoagulation therapy, and the IVC filter was retrieved. At the 3-month follow-up, the lower limb swelling completely disappeared, and the contrast-enhanced CT demonstrated the complete disappearance of the retroperitoneal hematoma and DVT. Discussion This case provided not only the potential value of the venous phase contrast-enhanced CT in diagnosing a spontaneous iliac vein rupture, but also the potential benefit of conservative management followed by elective EVT.


2016 ◽  
Vol 9 (4) ◽  
Author(s):  
Aamer Nadeem Chaudhry ◽  
Asim Shaukat ◽  
Syed Anjum Mehdi ◽  
Tahir Qadeer Khan ◽  
Muhammad Ali

Urinary bladder tumors are neoplasms which present as hematuria and sometimes if the lesion is small, then it becomes difficult to detect. We conducted this study to evaluate to different types of techniques for CT of urinary bladder. One with contrast filled urinary bladder and other with Contrast enhanced urinary bladder with the contrast not in the lumen of urinary bladder. 25 patients were evaluated, 18 of the cases were positive as far as the contrast filled bladder was concerned while 23 patients showed the abnormally enhancing bladder wall. 3 were negative in both techniques and were proven carcinoma on cystoscopy.


2020 ◽  
pp. 479-491
Author(s):  
Piero Boraschi ◽  
Gaia Tarantini ◽  
Federica Pacciardi ◽  
Francescamaria Donati

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