scholarly journals “AGGRESSIVE” CLEAR CELL CHONDROSARCOMA OF THE HARD PALATE

Author(s):  
Ajay M Bhandarkar ◽  
Balakrishnan Ramaswamy

Chondrosarcomas constitute 1 to 3% of all head and neck tumours. 2% of all chondrosarcomas are of the “clear cell” variety which follow a locally aggressive, relatively indolent course without predominant invasion of soft tissue. We present a 45-year-old woman presented with a bleeding mass in the oral cavity with change of voice of one year duration with pain of one month duration and histopathological analysis revealed a clear cell chondrosarcoma.

1970 ◽  
Vol 10 (1) ◽  
pp. 57-59
Author(s):  
M Irfan ◽  
RR Ramli ◽  
AK Shamim ◽  
A Pohchi

Although osteosarcoma is the most common primary bone cancer, the incidence in head and neck bony structures is extremely low. As the surgical treatment requires a wide margin excision, the operation usually will be very challenging especially if it involves midline structures. We report a case of a young gentleman who had a bony growth over the epicenter of the hard palate which rapidly occupies the whole oral cavity within 6 months duration. The outline of management is discussed. Keywords: Osteosarcoma; hard palate. DOI: 10.3329/bjms.v10i1.7322 Bangladesh Journal of Medical Science Vol.10 No.1 Jan 2010 pp.57-59


2011 ◽  
Vol 05 (03) ◽  
pp. 340-343 ◽  
Author(s):  
Ozkan Miloglu ◽  
Sare Sipal Altas ◽  
Mustafa Cemil Buyukkurt ◽  
Burak Erdemci ◽  
Oguzhan Altun

ABSTRACTRhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common soft tissue sarcoma encountered in childhood and adolescence. The common sites of occurrence are the head and neck region, genitourinary tract, retroperitonium, and, to a lesser extent, the extremities. In the head and neck region, the most commonly affected sites are the orbit, paranasal sinuses, soft tissues of the cheek, and the neck. RMS is relatively uncommon in the oral cavity, and the involvement of the jaws is extremely rare. Here, we report a case of oral RMS in a 13-year-old child and describe the clinical, radiological, histopathological, and immunohistochemical findings. (Eur J Dent 2011;5:340-343)


2013 ◽  
Vol 12 (4) ◽  
pp. 445-448
Author(s):  
AN Sulabha ◽  
S Choudhari ◽  
G Suchitra

Pyogenic granuloma is a benign, localized mass of exuberant granulation tissue produced in response to various stimuli. It is inflammatory hyperplasia of oral cavity commonly seen on gingival area and rarely on other parts of oral cavity such as lips, tongue, palate and buccal mucosa. It is seen predominantly in 2nd to 3rd decade of life in young females. Clinically manifesting as small red erythematous exophytic lesion, it must be biopsied to rule out other serious conditions. This article aims to present three cases of extra gingival pyogenic granulomas occurring in rare sites such as buccal mucosa, anterior hard palate and alveolar mucosa of completely edentulous ridge in maxilla. Pyogenic granuloma on buccal mucosa and anterior hard palate were seen in female patients with age of 40 years and 34 years respectively and pyogenic granuloma on alveolar mucosa of edentulous ridge in maxilla was noted in 70 years old male patient. Surgical excision was performed for all the lesion and follow up of one year did not show any recurrence. Please add little description of patient + treatment + followup results. DOI: http://dx.doi.org/10.3329/bjms.v12i4.16667 Bangladesh Journal of Medical Science Vol. 12 No. 04 October ’13 Page 445-448


2018 ◽  
Vol 6 (1) ◽  
pp. 15-19
Author(s):  
Namita Shrestha ◽  
Bhawana Dangol ◽  
Ishwor Raj Devkota ◽  
Ajit Nepal ◽  
Deepak Yadav ◽  
...  

Objective: To find out the prevalence of various types of head and neck trauma.Material and Methods: This retrospective study was done in the department of ENT and HNS, Patan Hospital, PAHS. Charts were retrospectively reviewed for total 61 inpatients with a diagnosis suggestive of head and neck trauma from August 2013 to January 2015. Data was collected for  age, sex, address, type of admission (emergency/OPD), mechanism of injury, site of injury , imaging including X-rays/CT scan wherever applicable and results, surgical therapy, type of anesthesia, hospital admission duration, complications, and follow-up and analyzed.Result: Males were common than females (62.3% vs. 37.7%).  Fall was the most common mode of injury (100%) in both pediatric and elderly population and in adults RTA (42.10%) was the most common mode. In the type of injury most common in pediatrics was oral cavity and oropharyngeal injury (47.60%), in adults facial soft tissue injury (STI) and facial fractures (42.10%) were equally common and in geriatrics  it was (100%).Conclusion: Adult males were prone to head and neck trauma mostly sustaining soft tissue injury (STI)  and fractures due to RTA and physical assult. Injury to oral cavity and oropharynx and STI due to fall is common in extreme of ages. Though the management out comes were good and no grave complications were reported in this study.Nepalese Journal of ENT Head and Neck Surgery, Vol. 6, No. 1, 2015 


2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S29-S30
Author(s):  
C M Tucker ◽  
J Liu ◽  
S M Gargano ◽  
C E Fundakowski

Abstract Casestudy: Clear cell sarcoma of soft tissue (CCSST) is a rare translocation-associated sarcoma which uncommonly presents in the head and neck region. Because the tumor expresses markers of melanocytic differentiation, it can be difficult to distinguish from malignant melanoma and epithelioid malignant peripheral nerve sheath tumor (MPNST), necessitating clinical correlation and ancillary testing specifically fluorescence in situ hybridization (FISH) for EWSR1 rearrangement. Here we report a case of CCSST involving the premaxillary soft tissue. A 61-year-old male without significant past medical history presented with a right premaxillary subcutaneous mass which was slowly enlarging over the course of three years. During surgical resection of the mass, the infraorbital nerve was noted to course into the tumor. Histologic sections revealed a 2.5 cm mass composed of a nodular proliferation of epithelioid tumor cells with pale eosinophilic to vacuolated cytoplasm, large vesicular nuclei with prominent nucleoli, areas of punctate necrosis, and a mitotic rate of 10 mitoses per 10 high power fields. Scattered multinucleated tumor giant cells were also present. No pigment was identified. By immunohistochemistry, the tumor cells were diffusely positive for SOX-10 and S-100 and negative for HMB45, MART1, MITF, inhibin, calretinin, p63 and smooth muscle actin. FISH was positive for EWSR1 rearrangement. Altogether, the morphologic, immunohistochemical and cytogenetic findings supported the diagnosis of CCSST. Because the surgical margins were negative for malignancy, the patient did not require additional surgery but will be receiving adjuvant radiation therapy. Although rare in the head and neck, CCSST should be considered in the differential diagnosis when dealing with an epithelioid soft tissue tumor that expresses any melanocytic markers, and a definitive distinction from malignant melanoma and epithelioid MPNST can be achieved by utilizing FISH for EWSR1 rearrangement.


2020 ◽  
Vol 162 (4) ◽  
pp. 498-503 ◽  
Author(s):  
Laith Mukdad ◽  
Albert Y. Han ◽  
Karam Badran ◽  
Jose E. Alonso ◽  
Hassan B. Nasser ◽  
...  

Objective To characterize the epidemiology and clinicopathologic determinants of survival following the diagnosis of clear cell adenocarcinoma in the head and neck region. Study Design Retrospective cohort study. Setting The Surveillance, Epidemiology, and End Results registry (1994 to 2014). Subjects and Methods A total of 173 cases were identified. Study variables included age, sex, race, tumor subsite, tumor stage, tumor grade, surgical excision, and regional and distant metastases. Survival measures included overall survival (OS) and disease-specific survival (DSS). Results Median age at diagnosis was 63 years, 48% were female, and 80.2% were white. Fourteen percent of patients presented with regional lymph node metastases, while 3.3% of patients presented with distant metastases. Most of the tumors presented in the oral cavity, salivary glands, and pharynx. Kaplan-Meier analysis demonstrated OS and DSS of 77.2% and 83.7% at 5 years, respectively. Median OS after diagnosis was 153 months. Bivariate analysis showed that surgical excision was associated with 5-fold increased OS and DSS, whereas advanced age, high tumor grade, advanced stage, larger tumor size, nodal disease, and distant metastases were all significant predictors of decreased OS and DSS. Conclusions Clear cell adenocarcinoma is a rare neoplasm that typically affects white individuals in their early 60s, with a generally favorable prognosis. It most commonly arises in the oral cavity, major salivary glands, and pharynx. Surgical excision is associated with 5-fold survival benefit, whereas advanced age, high tumor grade, advanced stage, nodal disease, and distant metastases are independently associated with worse OS and DSS.


2012 ◽  
Vol 4 (1) ◽  
Author(s):  
Sepideh Mokhtari ◽  
Abbas Mirafsharieh

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Paolo Vescovi ◽  
Marco Meleti ◽  
Elisabetta Merigo ◽  
Maddalena Manfredi ◽  
Domenico Corradi ◽  
...  

Chondromas are benign cartilaginous tumors usually localized within the tubular bones of the extremities. Soft tissue chondromas (STCs) are rare and only few cases have been reported in the oral cavity. The present case documents the exceptional finding of a 12-year-standing STC of the hard palate of a 63-year-old man. The tumor measured approximately 6 cm in its larger size and it was radically excised through the use of a quantic resonance molecular (QRM) lancet. No recurrence was observed during 1-year follow-up. A concise review of the relevant literature is included in the present paper.


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