scholarly journals ROLE OF LEVOFLOXACIN FOR TREATMENT OF CHRONIC SUPPURATIVE OTITIS MEDIA: SAMPLE OF IRAQI PATIENTS

2017 ◽  
Vol 10 (9) ◽  
pp. 358 ◽  
Author(s):  
Safaa Sahib Naji Sultan ◽  
Malath Azeez Alsaady
Keyword(s):  
Otitis Media ◽  
Age Groups ◽  
Chronic Suppurative Otitis Media ◽  
Klebsiella Species ◽  
Suppurative Otitis Media ◽  
Oral Tablet ◽  
Sensitivity Tests ◽  
Promising Treatment ◽  
A Prospective Study

  Objective: To evaluate levofloxacin efficiency for treatment of chronic suppurative otitis media in sample of Iraqi patients.Methods: This is a prospective study which includes 50 patients of different age groups diagnosed with CSOM. Aural toilet and otosporin ear drop performed in clinic, then levofloxacin prescribed as single oral tablet daily for 4-6 weeks. Patients were examined every 2 weeks for 8 weeks and then once by month for 6 months to evaluate the efficiency of treatment.Results: Forty patients (80%) showed complete dryness and healing. Discharge decreased upon the visits with more dryness observed after 4 weeks of treatment. Signs of healing and tympanic perforation closure apparently occur about 1 month from the initial treatment in 32 patients (80% of successful treatment). Culture sensitivity tests results were Pseudomonas aeruginosa and Klebsiella species in discharge materials.Conclusion: Levofloxacin is a safe and effective drug for the treatment of CSOM and promising treatment for CSOM in combination with aural toilet. The main species of microorganism detected were P. aeruginosa and Klebsiella.

Frequency of Incus Bone Erosion on Mastoid Exploration in Chronic Suppurative Otitis Media with Middle Ear Cholesteotoma

2021 ◽  
Vol 15 (6) ◽  
pp. 1426-1428
Author(s):  
W. Javaid ◽  
A. Rashid ◽  
M. U. K. Amin ◽  
T. Khan ◽  
M. Fatima
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Bone Erosion ◽  
Age Groups ◽  
Chronic Suppurative Otitis Media ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Middle Ear Cholesteatoma ◽  
Sample Technique ◽  
Operative Findings

Background: Cholesteotoma is a benign but destructive lesion leading to ossicular necrosis. Objective: To see the frequency of incus bone erosion on mastoid exploration in chronic suppurative otitis media with middle ear cholesteotoma. Study Design: Cross-sectional descriptive study. Setting: This study was carried out in the Department of ENT Unit-2, Sir Ganga Ram Hospital, Lahore. Duration of Study: Fifteen months months (10th April, 2019 to 9th July, 2020) Sample technique: Non- probability purposive sampling Methods: One hundred and twenty patients were admitted through outpatient department of ENT Unit-2, Sir Ganga Ram Hospital Lahore. Patients were included after fulfilling the inclusion criteria and information was collected on a prescribed proforma. Finally during surgery under general anesthesia, the operative findings were noted to know the incus bone erosion after middle ear cholesteatoma formation in chronic suppurative otitis media. Results: A total number of one hundred and twenty patients of chronic suppurative otitis media with middle ear cholesteatoma were included. Out of which 80 (66.7%) were males and 40 (33.3%) were females(Table 1).The patients shown in table 2 were divided in six age groups (Table 2).Table 3 shows that the procedure of mastoidectomy was performed in 112 patients (93.3%) and modified radial mastoidectomy was performed in 8 patients (6.7%).Incus bone erosion in chronic suppurative otitis media with middle ear cholesteatoma in 102 patients (85%) and 18 patients (15%) have no incus bone erosion (Table 4). Conclusion: Ear discharge was the most common presenting characteristic of chronic suppurative otitis media with cholesteatoma. The majority of the cases had ossicular erosion, with the incus being the most common site of involvement. Males are more likely than females to develop cholesteatoma. Keywords: erosion of incus bone, Mastoid exploration, Chronic suppurative otitis media, Cholesteatoma

Quantitative Bacterial Cultures and Beta-Lactamase Activity in Chronic Suppurative Otitis Media

1989 ◽  
Vol 98 (4) ◽  
pp. 293-297 ◽  
Author(s):  
Itzhak Brook ◽  
Paula Yocum
Keyword(s):  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Aerobic Bacteria ◽  
Suppurative Otitis Media ◽  
Colony Forming Units ◽  
Penicillin Therapy ◽  
Aerobic And Anaerobic ◽  
And Staphylococcus Aureus ◽  
Gram Positive Cocci

Aspiration of the exudate through open perforation was performed in 54 children with chronic suppurative otitis media. Eighty aerobic and 81 anaerobic isolates were recovered. Aerobic bacteria only were involved in 20 patients (37%), and anaerobic organisms only in seven (13%). Mixed aerobic and anaerobic isolates were recovered from 27 patients (50%). The most common bacteria isolated were anaerobic gram-positive cocci, Bacteroides melaninogenicus group, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. There were 45 β-lactamase–producing bacteria (BLPB), 30 aerobes, and 15 anaerobes recovered from 38 patients (70%). β-Lactamase activity was detected in 30 of the 38 ear aspirates (79%) that contained BLPB. All but one of these organisms were in excess of 104 colony-forming units/mL. The detection of β-lactamase activity in the ear aspirates provides evidence of the role of BLPB in the failure of penicillin therapy to eradicate chronic ear infection.

Aerobic Bacteriology of Chronic Suppurative Otitis Media without Cholesteatoma in Children

1992 ◽  
Vol 101 (10) ◽  
pp. 866-869 ◽  
Author(s):  
Dan M. Fliss ◽  
Naftali Meidan ◽  
Ron Dagan ◽  
Alberto Leiberman
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Prospective Study ◽  
Otitis Media ◽  
Granulation Tissue ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Gram Negative ◽  
Nonsurgical Management ◽  
A Prospective Study

Medical management of chronic suppurative otitis media without cholesteatoma in children was shown recently to be efficacious. We undertook a prospective study in order to determine 1) the organisms associated with the disease and their sensitivity to various antibiotics and 2) their association with clinical variables. Pseudomonas was isolated from 84% of the patients, enteric gram-negative bacilli from 32%, Staphylococcus aureus from 20%, streptococci from 14%, and Hemophilus influenzae from 15%. Pseudomonas aeruginosa was the sole isolate in 48 of the 128 patients (38%). The sensitivity of P aeruginosa (78 isolates) was 100% (of isolates) to mezlocillin and ciprofloxacin, 99% to tobramycin and ceftazidime, 97% to piperacillin, 94% to gentamicin, and 78% to ceftriaxone. The isolated organisms and their sensitivity to antibiotics were not associated with age, sex, duration of otorrhea, or the presence of granulation tissue or polyps. We believe that our data may contribute to the appropriate choice of antibiotics when nonsurgical management of chronic suppurative otitis media without cholesteatoma is considered.

scholarly journals Microbiological Study of Chronic Suppurative Otitis Media

2019 ◽  
Vol 46 (2) ◽  
pp. 7-9
Author(s):  
Rifat Nousin Shumi ◽  
Abdullah Siddiqe ◽  
Arefa Akter
Keyword(s):  
Otitis Media ◽  
Age Groups ◽  
Chronic Suppurative Otitis Media ◽  
Klebsiella Pneumonia ◽  
Biochemical Tests ◽  
College Hospital ◽  
Suppurative Otitis Media ◽  
Medical College ◽  
Microbiological Profile ◽  
Gram Staining

Chronic suppurative otitis media (CSOM) is a prevailing and notorious infection in developing countries causing serious local damage and threatening complications. The purpose of the present study was determine the microbiological profile of isolates from discharge in CSOM. This study was conducted at out-patient department of ENT at Rajshahi Medical College Hospital, Rajshahi from January 2014 to December 2014. Samples were taken from 185 patients (both male and female) in all age groups suffering from chronic suppurative otitis media. Their Gram staining, culture, and biochemical tests were carried out to identify the organisms. It showed the predominance by staphylococcus aereus (29.13%), followed by Pseudomonas Aeruginosa (22.83%), Streptococcus Pyogen (14.96%), E.Coli (9.44%), Proteus Mirabilis (6.29%), Klebsiella Pneumonia ( 4.72%). Bangladesh Med J. 2017 May; 46 (2): 7-9

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