VATS-US1: Thoracoscopic ultrasonography for the identification of nodules during lung metastasectomy

2020 ◽  
Vol 16 (5) ◽  
pp. 85-89
Author(s):  
Francesco Londero ◽  
Luigi Castriotta ◽  
William Grossi ◽  
Gianluca Masullo ◽  
Angelo Morelli ◽  
...  

Open thoracotomy during pulmonary metastasectomy allows lung palpation and may discover unexpected further nodules. We assess the validity of intraoperative lung ultrasonography via thoracoscopy in identifying lung nodules. A first surgeon will perform an ultrasonographic investigation on the deflated lung by thoracoscopy. A second surgeon will then perform a manual exploration of the organ by thoracotomy. Data on number and localization of nodules will be matched and compared with final histology report. Sensitivity and specificity will be assessed. Concordance will be assessed with Cohen K test. Calculated sample size is 89 patients. This study might have an important role in shifting the surgical practice towards a less invasive approach, with consequent benefits for the patient. Protocol is registered on clinicaltrials.gov . Protocol registration number: NCT03864874.

2020 ◽  
Author(s):  
Kenan Can Ceylan ◽  
Güntuğ Batıhan ◽  
Seyda Ors Kaya

Abstract Background Metastasis is remaining one of the major problems in cancer treatment. Like many other malignancies, urogenital tumors originating from kidney, prostate, testes, and bladder tend to metastasize to the lungs.The aim of this retrospective study is to evaluate the results of pulmonary metastasectomy in patients with primary urogenital tumors.Methods This study was approved by the local ethical committee. This study retrospectively analyses the patients who underwent lung resections for metastases in our department between 2002 and 2018. 22 out of 126 patients referred for pulmonary metastasectomy to our department had metastases from urogenital tumors.Demographic data and clinicopathological features were extracted from the medical records. Disease-free interval (DFI) was defined as the time between the first curative surgery and the detection of pulmonary metastasis. Results Among 22 patients who underwent lung metastasectomy consisted of 17 males and five females. Their metastasis originated from renal cell carcinoma (RCC; n = 9), bladder tumor (n = 7), testis tumors (n = 4), and prostate cancer (n = 2). There was no intraoperative complication. Postoperative complications were seen in 2 patients. Conclusions Although pulmonary metastases and its surgical management in various types of tumors is well known and documented, the data is limited to the role of the surgery for metastases of urogenital cancers on literature. Despite the limitations of this study, we aim to document our promising results of pulmonary metastasectomy in patients with primary urogenital tumors.Trial registration This study was approved by the local ethical committee (Registration number: 49109414-604.02 ; Date: 11/06/2019).


Author(s):  
Petar Risteski ◽  
Nadejda Monsefi ◽  
Aleksandra Miskovic ◽  
Tanja Josic ◽  
Sherife Bala ◽  
...  

2005 ◽  
Vol 13 (4) ◽  
pp. 399-405 ◽  
Author(s):  
Gisele Quariguasi Tobias Lima ◽  
Eurípedes Gomes Oliveira ◽  
João Inácio Lima de Souza ◽  
Valério Monteiro Neto

The methods of caries removal have been the subject of many studies over the last years. At present, methods involving the least tissue invasion have been outstanding in the field of surgical-restorative treatment. In this context, the Carisolv™ system has appeared as a less traumatic and less invasive approach, particularly in pedodontics. Thus, the objective of the present study was to carry out a comparative analysis of the dentinal structure of primary molars before and after the removal of carious tissue by mechanical (low speed drills and conventional dentinal curettes) and chemomechanical (Carisolv™ kit) procedures based on quantitative culture for cariogenic bacteria to determine the number of bacteria present in the carious dentine after both treatments. Sixty primary molars from children ranging in age from 4 to 8 years, with active occlusal caries in dentine, were divided into two groups (A and B) of 30 teeth each, with group A having been treated by the chemomechanical technique and group B by the mechanical technique. Dentin samples were placed in glass vials containing 1 mL thioglycolate broth and submitted to culture to determine the number of S. mutans and Lactobacillus per mg of decayed dentine. The results did not reveal significant differences between the two methods of caries removal; however, the chemomechanical method was more efficient in completely eliminating S. mutans (p=0.02). In summary, the present results confirm previous studies showing that the two methods are comparable in reducing Lactobacillus, but Carisolv™ is more effective in the elimination of S. mutans.


2019 ◽  
Vol 5 (1) ◽  
pp. 205511691985064
Author(s):  
Margaret Amparo Placer ◽  
Cindy McManis

Case summary A 6-month-old male domestic shorthair cat presenting with abdominal distension and an acute history of renal azotemia was diagnosed with bilateral perinephric pseudocysts and International Renal Interest Society (IRIS) grade 3 acute kidney injury. Ultrasound-guided drainage of the cysts was performed initially; bilateral subtotal resection of the perinephric pseudocysts was later performed using laparoscopy as a more long-term solution. There was no regrowth or reformation of the perinephric pseudocysts 1 year after the procedure, and the cat remained in IRIS stage 2 chronic kidney disease 1 year postoperatively. Relevance and novel information Compared with traditional surgical approaches, laparoscopic resection of perinephric pseudocysts provides a less invasive approach. Bilateral perinephric pseudocyst in a pediatric feline patient (and associated treatment) has not previously been documented in the literature.


PEDIATRICS ◽  
1996 ◽  
Vol 98 (3) ◽  
pp. 464-466
Author(s):  
Timothy K. Flannery ◽  
John L. Kirkland ◽  
Kenneth C. Copeland ◽  
Alison A. Bertuch ◽  
Lefkothea P. Karaviti ◽  
...  

A less-invasive approach to the evaluation of papillary carcinoma in children and adolescents recently has been proposed, based on reports of the accuracy and reliability of fine-needle aspiration biopsy (FNAB) in this population.1-4 Such confidence may be ill-founded, as the following clinical histories will illustrate. Functioning nodules, Hashimoto's thyroiditis (HT), and goiter-associated lymphadenopathy are unusual but significant presentations of papillary carcinoma in children and young adults, likely to be missed by the standard diagnostic approach in adults, which is reliant on FNAB, 123I scintiscans, or clinical response to suppressive doses of L-thyroxine (T4). CASE REPORTS Case 1 A thyroid nodule developed in a 12-year-old girl, first observed 1 month before evaluation in an endocrine clinic.


1996 ◽  
Vol 16 (2) ◽  
pp. 76-82
Author(s):  
T Shawgo

VATS offers numerous advantages for patients with pulmonary disease. Diagnosis and management of numerous pulmonary and other thoracic conditions can now be treated with a less invasive approach. Because of this advance in technology, the ICU patient population is changing. With this advance, there will be fewer thoracotomies performed, resulting in fewer ICU admissions. Thoracoscopy offers hope for those critically ill patients who cannot withstand a diagnosis or interventional surgical procedure to treat their illness.


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