scholarly journals The inclusion of health data standards in the implementation of pharmacogenomics systems: a scoping review

2020 ◽  
Vol 21 (16) ◽  
pp. 1191-1202 ◽  
Author(s):  
Don Roosan ◽  
Angela Hwang ◽  
Anandi V Law ◽  
Jay Chok ◽  
Moom R Roosan

Background: Despite potential benefits, the practice of incorporating pharmacogenomics (PGx) results in clinical decisions has yet to diffuse widely. In this study, we conducted a review of recent discussions on data standards and interoperability with a focus on sharing PGx test results among health systems. Materials & methods: We conducted a literature search for PGx clinical decision support systems between 1 January 2012 and 31 January 2020. Thirty-two out of 727 articles were included for the final review. Results: Nine of the 32 articles mentioned data standards and only four of the 32 articles provided solutions for the lack of interoperability. Discussions: Although PGx interoperability is essential for widespread implementation, a lack of focus on standardized data creates a formidable challenge for health information exchange. Conclusion: Standardization of PGx data is essential to improve health information exchange and the sharing of PGx results between disparate systems. However, PGx data standards and interoperability are often not addressed in the system-level implementation.

2020 ◽  
Vol 29 (01) ◽  
pp. 104-114
Author(s):  
Ursula H. Hübner ◽  
Nicole Egbert ◽  
Georg Schulte

Objective: The more people there are who use clinical information systems (CIS) beyond their traditional intramural confines, the more promising the benefits are, and the more daunting the risks will be. This review thus explores the areas of ethical debates prompted by CIS conceptualized as smart systems reaching out to patients and citizens. Furthermore, it investigates the ethical competencies and education needed to use these systems appropriately. Methods: A literature review covering ethics topics in combination with clinical and health information systems, clinical decision support, health information exchange, and various mobile devices and media was performed searching the MEDLINE database for articles from 2016 to 2019 with a focus on 2018 and 2019. A second search combined these keywords with education. Results: By far, most of the discourses were dominated by privacy, confidentiality, and informed consent issues. Intertwined with confidentiality and clear boundaries, the provider-patient relationship has gained much attention. The opacity of algorithms and the lack of explicability of the results pose a further challenge. The necessity of sociotechnical ethics education was underpinned in many studies including advocating education for providers and patients alike. However, only a few publications expanded on ethical competencies. In the publications found, empirical research designs were employed to capture the stakeholders’ attitudes, but not to evaluate specific implementations. Conclusion: Despite the broad discourses, ethical values have not yet found their firm place in empirically rigorous health technology evaluation studies. Similarly, sociotechnical ethics competencies obviously need detailed specifications. These two gaps set the stage for further research at the junction of clinical information systems and ethics.


2020 ◽  
Author(s):  
Philip Scott ◽  
Elisavet Andrikopoulou ◽  
Haythem Nakkas ◽  
Paul Roderick

Background: The overall evidence for the impact of electronic information systems on cost, quality and safety of healthcare remains contested. Whilst it seems intuitively obvious that having more data about a patient will improve care, the mechanisms by which information availability is translated into better decision-making are not well understood. Furthermore, there is the risk of data overload creating a negative outcome. There are situations where a key information summary can be more useful than a rich record. The Care and Health Information Exchange (CHIE) is a shared electronic health record for Hampshire and the Isle of Wight that combines key information from hospital, general practice, community care and social services. Its purpose is to provide clinical and care professionals with complete, accurate and up-to-date information when caring for patients. CHIE is used by GP out-of-hours services, acute hospital doctors, ambulance service, GPs and others in caring for patients. Research questions: The fundamental question was How does awareness of CHIE or usage of CHIE affect clinical decision-making? The secondary questions were What are the latent benefits of CHIE in frontline NHS operations? and What is the potential of CHIE to have an impact on major NHS cost pressures? The NHS funders decided to focus on acute medical inpatient admissions as the initial scope, given the high costs associated with hospital stays and the patient complexities (and therefore information requirements) often associated with unscheduled admissions. Methods: Semi-structured interviews with healthcare professionals to explore their experience about the utility of CHIE in their clinical scenario, whether and how it has affected their decision-making practices and the barriers and facilitators for their use of CHIE. The Framework Method was used for qualitative analysis, supported by the software tool Atlas.ti. Results: 21 healthcare professionals were interviewed. Three main functions were identified as useful: extensive medication prescribing history, information sharing between primary, secondary and social care and access to laboratory test results. We inferred two positive cognitive mechanisms: knowledge confidence and collaboration assurance, and three negative ones: consent anxiety, search anxiety and data mistrust. Conclusions: CHIE gives clinicians the bigger picture to understand the patient's health and social care history and circumstances so as to make confident and informed decisions. CHIE is very beneficial for medicines reconciliation on admission, especially for patients that are unable to speak or act for themselves or who cannot remember their precise medication or allergies. We found no clear evidence that CHIE has a significant impact on admission or discharge decisions. We propose the use of recommender systems to help clinicians navigate such large volumes of patient data, which will only grow as additional data is collected.


2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Rogier van de Wetering

Modern hospitals increasingly make use of innovations and information technology (IT) to improve workflow and patient’s clinical journey. Typical innovative solutions include patient records and clinical decision support systems to enhance the process of decision making by doctors and other healthcare practitioners. However, currently, it remains unclear how hospitals could facilitate and enable such a decision support capability in clinical practice. We ground our work on the resource-based view of the firm and put forth the notion of IT-enabled capabilities which emphasizes critical IT investment and capability development areas that hospitals could exploit in their quest to improve clinical decision support. We develop a research model that explains how “health information exchange” and enhanced “information capability” collectively drive a hospital’s “clinical decision support capability.” We used partial least squares path modeling on large-scale cross-sectional data from 720 European hospitals. Outcomes suggest that health information exchange positively impacts information capability. In turn, information capability complementary partially mediates the relationship between information exchange and clinical decision support. Hence, this research contributes to the literature on clinical decision support and provides valuable insights into how to support such innovative technologies and capabilities in clinical practice. We conclude with a discussion and conclusion. Also, we outline the inherent limitations of this study and outline directions for future research.


2013 ◽  
Vol 22 (01) ◽  
pp. 13-19 ◽  
Author(s):  
A. B. McCoy ◽  
A. Wright ◽  
G. Eysenbach ◽  
B. A. Malin ◽  
E. S. Patterson ◽  
...  

Summary Objective: The field of clinical informatics has expanded substantially in the six decades since its inception. Early research focused on simple demonstrations that health information technology (HIT) such as electronic health records (EHRs), computerized provider order entry (CPOE), and clinical decision support (CDS) systems were feasible and potentially beneficial in clinical practice. Methods: In this review, we present recent evidence on clinical informatics in the United States covering three themes: 1) clinical informatics systems and interventions for providers, including EHRs, CPOE, CDS, and health information exchange; 2) consumer health informatics systems, including personal health records and web-based and mobile HIT; and 3) methods and governance for clinical informatics, including EHR usability; data mining, text mining, natural language processing, privacy, and security. Results: Substantial progress has been made in demonstrating that various clinical informatics methodologies and applications improve the structure, process, and outcomes of various facets of the healthcare system. Conclusion: Over the coming years, much more will be expected from the field. As we move past the “early adopters” in Rogers' diffusion of innovations' curve through the “early majority” and into the “late majority,” there will be a crucial need for new research methodologies and clinical applications that have been rigorously demonstrated to work (i.e., to improve health outcomes) in multiple settings with different types of patients and clinicians.


2014 ◽  
Vol 22 (3) ◽  
pp. 519-528 ◽  
Author(s):  
Guilherme Del Fiol ◽  
Barbara Insley Crouch ◽  
Mollie R Cummins

Abstract Objective Poison control centers (PCCs) routinely collaborate with emergency departments (EDs) to provide care for poison-exposed patients. During this process, a significant amount of information is exchanged between EDs and PCCs via telephone, leading to important inefficiencies and safety vulnerabilities. In the present work, we identified and assessed a set of data standards to enable a standards-based health information exchange process between EDs and PCCs. Materials and methods Based on a reference model for PCC–ED health information exchange, we (1) mapped PCC–ED information exchange events to clinical documents specified in the Health Level Seven (HL7) Consolidated Clinical Document Architecture (C-CDA) Standard, and (2) mapped information types routinely exchanged in PCC–ED telephone conversations to C-CDA sections. Results Four C-CDA document types were necessary to support the PCC–ED information exchange process: History & Physical Note, Consultation Note, Progress Note, and Discharge Summary. Information types that are commonly exchanged between PCCs and EDs can be reasonably well represented within these C-CDA documents. Conclusions A standards-based health information exchange process between PCCs and EDs appears to be feasible given a set of clinical data standards that are required for EHR certification in the USA, although the proposed approach still needs to be validated in actual system implementations. Such a process has the potential to improve the safety and efficiency of PCC–ED communication, ultimately resulting in improved patient care outcomes.


2020 ◽  
pp. 328-350
Author(s):  
Basmah Almoaber ◽  
Daniel Amyot

Background: Despite the potential benefits of health information exchange (HIE) and the two decades of efforts from the Canadian and the American governments to promote health exchange projects, failures far outnumber successes. Objective: To better understand the barriers influencing the adoption and implementation of inter-organization HIE systems in Canada and the USA. Method: A systematic literature review was conducted to examine English-language studies that identified barriers to HIE in Canada and the USA between 1995 and 2016. Electronic databases, backward searching and expert consultations were used. Results: 31 articles have been included. There is a dearth of publications reported on the HIE barriers in Canada. A total of 33 barriers have been identified. Conclusion: There are noticeable differences in the barriers reported in these countries. Privacy concerns and a lack of stakeholder buy-in are recurring barriers over time in the USA. Low adoption of electronic medical records is the main barrier in Canada.


2020 ◽  
Vol 54 (4) ◽  
pp. 389-390
Author(s):  
Harneet Kaur ◽  
Arisha Izhar

The largest public health crisis of our time, COVID-19 has recklessly squandered many of the channelized healthcare facilities globally with execution of newer guidelines over the standard architectural norms. There has been unparalleled use of smartphones and internet services to bear the major pitfall- social distancing- especially for elective treatment services. This demands a new paradigm shift from offline to online doctor-patient, student-educator, researcher-researcher operations. This articles provides an insight into potential role of orthodontic informatics to provide a combined platform to generate a learning system that routinely collects, correlates, and analyzes data for developing artificial intelligence programs, lab exploratory systems, clinical decision support systems and health-information exchange systems. In order to develop this system, orthodontic analytic communities as start-ups for developing user-friendly programs must be encouraged, where orthodontic informatics itself can be taken up as a didactic career source.


Author(s):  
Basmah Almoaber ◽  
Daniel Amyot

Background: Despite the potential benefits of health information exchange (HIE) and the two decades of efforts from the Canadian and the American governments to promote health exchange projects, failures far outnumber successes. Objective: To better understand the barriers influencing the adoption and implementation of inter-organization HIE systems in Canada and the USA. Method: A systematic literature review was conducted to examine English-language studies that identified barriers to HIE in Canada and the USA between 1995 and 2016. Electronic databases, backward searching and expert consultations were used. Results: 31 articles have been included. There is a dearth of publications reported on the HIE barriers in Canada. A total of 33 barriers have been identified. Conclusion: There are noticeable differences in the barriers reported in these countries. Privacy concerns and a lack of stakeholder buy-in are recurring barriers over time in the USA. Low adoption of electronic medical records is the main barrier in Canada.


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