scholarly journals Editorial – Infectious-disease research during a pandemic: the importance of global unity

2021 ◽  
Vol 42 ◽  
pp. 154-155
Author(s):  
W-J Metsemakers ◽  
◽  
HC van der Mei ◽  
RG Richards ◽  
TF Moriarty

The orthopaedic and trauma community have faced the threat of infection since the introduction of operative fracture fixation many decades ago. The parallel emergence and spread of antimicrobial resistance in clinically relevant pathogens has the potential to significantly complicate patient care. This editorial serves to provide a global context to the issue of antimicrobial resistance and how infectious disease research in general plays a crucial role both on a global scale as evidenced by the current pandemic, but also on a more personal scale for the daily management of orthopaedic trauma patients. The special issue on Orthopaedic Infection in the eCM journal provides a snapshot of the clinically relevant basic research that is being performed in this field.

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Hee-Gyeong Yi ◽  
Hyeonji Kim ◽  
Junyoung Kwon ◽  
Yeong-Jin Choi ◽  
Jinah Jang ◽  
...  

AbstractRapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional infectious disease models and by employing advanced technology for the production of medicine and cell/drug delivery systems. In this regard, layer-by-layer construction with a 3D bioprinting system or other technologies provides a beneficial method for developing highly biomimetic and reliable in vitro models for infectious disease research. In addition, the high flexibility and versatility of 3D bioprinting offer advantages in the effective production of vaccines, therapeutics, and relevant delivery systems. Herein, we discuss the potential of 3D bioprinting technologies for the control of infectious diseases. We also suggest that 3D bioprinting in infectious disease research and drug development could be a significant platform technology for the rapid and automated production of tissue/organ models and medicines in the near future.


2015 ◽  
Vol 3 ◽  
Author(s):  
James C. Bartholomew ◽  
Andrew D. Pearson ◽  
Nils Chr. Stenseth ◽  
James W. LeDuc ◽  
David L. Hirschberg ◽  
...  

Science ◽  
2015 ◽  
Vol 349 (6252) ◽  
pp. 1259504-1259504 ◽  
Author(s):  
P. T. J. Johnson ◽  
J. C. de Roode ◽  
A. Fenton

2020 ◽  
Vol 8 (5) ◽  
pp. 645
Author(s):  
Kim Stanford

Antimicrobial resistance threatens the health of both humans and livestock as antimicrobials become continually less effective for controlling infectious disease [...]


2019 ◽  
Vol 20 (6) ◽  
pp. 323-340 ◽  
Author(s):  
Maria A. Spyrou ◽  
Kirsten I. Bos ◽  
Alexander Herbig ◽  
Johannes Krause

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