scholarly journals A Case Report on Korean Medical Treatment of a Patient with Abnormal Liver Function Induced by Rovazet

2021 ◽  
Vol 42 (5) ◽  
pp. 846-852
Author(s):  
Hee-kyung Kang ◽  
Im-hak Cho ◽  
Chan Lee ◽  
Gi-yoon Heo ◽  
Min-hwa Kim ◽  
...  
Keyword(s):  
Liver Function ◽  
Clinical Case ◽  
Acupuncture Treatment ◽  
Clinical Symptoms ◽  
Abnormal Liver Function ◽  
Lipid Lowering ◽  
Test Results ◽  
Laboratory Test Results ◽  
Lipid Lowering Agent ◽  
Intradermal Acupuncture

Objective: This study evaluated a clinical case of a patient with Rovazet-induced abnormal liver function treated with intradermal acupuncture.Method: A 59-year-old woman with abnormal liver function induced by Rovazet ceased taking the drug and instead received intradermal acupuncture treatment. After 15 days, clinical symptoms and laboratory test results were evaluated.Results: Aspartate aminotransferase and alanine aminotransferase levels decreased, and clinical symptoms such as nausea and fatigue improved after treatment with intradermal acupuncture and cessation of the Rovazet.Conclusion: This study meaningfully examined a clinical case of a patient with abnormal liver function induced by a lipid-lowering agent, which is uncommon in Korea. Unfortunately, the lack of clear evidence and the use of only one case are limitations of the study.

scholarly journals Hepatic Manifestations in Hematological Disorders

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Jun Murakami ◽  
Yukihiro Shimizu
Keyword(s):  
Liver Function ◽  
Clinical Symptoms ◽  
Liver Function Tests ◽  
Hematologic Malignancies ◽  
Abnormal Liver Function ◽  
Abnormal Liver Function Test ◽  
Liver Imaging ◽  
Test Results ◽  
Hematological Disorders ◽  
Function Test

Liver involvement is often observed in several hematological disorders, resulting in abnormal liver function tests, abnormalities in liver imaging studies, or clinical symptoms presenting with hepatic manifestations. In hemolytic anemia, jaundice and hepatosplenomegaly are often seen mimicking liver diseases. In hematologic malignancies, malignant cells often infiltrate the liver and may demonstrate abnormal liver function test results accompanied by hepatosplenomegaly or formation of multiple nodules in the liver and/or spleen. These cases may further evolve into fulminant hepatic failure.

scholarly journals Prevalence and Course of SARS-CoV-2 Infection among Immunocompromised Children Hospitalised in the Tertiary Referral Hospital in Poland

2021 ◽  
Vol 10 (19) ◽  
pp. 4556
Author(s):  
Karolina Kuczborska ◽  
Janusz Książyk
Keyword(s):  
Laboratory Test ◽  
Clinical Characteristics ◽  
Chronic Treatment ◽  
Clinical Symptoms ◽  
Referral Hospital ◽  
Test Results ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Laboratory Test Results ◽  
Underlying Diseases

The aim of this retrospective study was the assessment of the prevalence, clinical characteristics, and the comparison of the course of SARS-CoV-2 infection in children with and without immunodeficiency that were admitted to the COVID-19 Subunit of the tertiary referral hospital in Warsaw, Poland. We analysed 313 children hospitalised in the COVID-19 Subunit. The analysis was performed on the total study group and subgroups of children with and without immunodeficiency. In each group, clinical data and laboratory test results were analysed. Of the 68 children with isolated fevers, only seven (11.76%) were diagnosed with COVID-19, whereas among those with the accompanying features of respiratory or gastrointestinal infection, only one (3.23%) and ten (16.95%) patients tested positive, respectively. In both groups, the course of the infection was mainly asymptomatic or mild. The children with immunodeficiencies had lower white blood cell and lymphocyte counts, lower haemoglobin levels, and higher urea levels but did not differ in other biochemical variables. To conclude, the most frequently reported symptoms of COVID-19 indicate that this disease among children is only a small percentage. In both groups, the responses to the infection were comparable in terms of the mild clinical symptoms and the laboratory test results. Therefore, SARS-CoV-2 infection should not alter the chronic treatment of underlying diseases.

scholarly journals Epidemiological and Clinical Features of COVID-19 Patients at National Emergency Hospital Wisma Atlet Kemayoran, Jakarta,Indonesia

2021 ◽  
Author(s):  
Agus Dwi Susanto ◽  
Anna Rozaliyani ◽  
Budi Prasetyo ◽  
Heidy Agustin ◽  
Hario Baskoro ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Young Patients ◽  
Patient Characteristics ◽  
Test Results ◽  
Emergency Hospital ◽  
Laboratory Test Results ◽  
Number Of Patients ◽  
Chest X Ray ◽  
The Many ◽  
National Emergency

The emergency hospital is intended to prevent transmission of COVID-19 in the community by isolating patients without symptoms, with mild or moderate symptoms. This study evaluated the clinical characteristics and outcomes of COVID-19 patients who were admitted to this facility. This retrospective study reviewed data of patients treated at the National Emergency Hospital Wisma Atlet Kemayoran in Jakarta, Indonesia, from March 23 to April 30, 2020. Patient characteristics (clinical symptoms, laboratory test results, Chest X-Ray, SARS-CoV-2 immunoserology, and RT-PCR results from nasopharyngeal/ oropharyngeal preparations) were compared between severity groups. There were 413 COVID-19 cases analyzed, of which 190 (46%) were asymptomatic, 93 (22.5%) were mild, and 130 (31.5%) were moderate cases. Most asymptomatic cases were male, with young age, and without comorbidity. Mild cases were dominated by female and young patients, while most moderate cases were male and older patients. The number of patients with comorbidities was higher in mild and moderate cases. The patient’s overall outcome was good and did not differ based on the severity of symptoms. Despite the many challenges, patients with moderate symptoms can be safely treated in the emergency hospital.

scholarly journals Preliminary study to identify severe from moderate cases of COVID-19 using NLR&RDW-SD combination parameter

2020 ◽  
Author(s):  
Changzheng Wang ◽  
Rongrong Deng ◽  
Liyao Gou ◽  
Zhongxiao Fu ◽  
Xiaomei Zhang ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Diagnostic Efficiency ◽  
Test Results ◽  
Laboratory Test Results ◽  
Severe Group ◽  
Preliminary Study ◽  
Hematology Parameters ◽  
And Control ◽  
Combined Parameters ◽  
Severe Type

AbstractObjectivesInvestigate the characteristics and rules of hematology changes in patients with COVID-19, and explore the possibility to identify moderate and severe patients using conventional hematology parameters or combined parameters.MethodsThe clinical data of 45 moderate and severe type patients with SARS-CoV-2 infections in Jingzhou Central Hospital from January 23 to February 13, 2020 were collected. The epidemiological indexes, clinical symptoms and laboratory test results of the patients were retrospectively analyzed. Those parameters with significant differences between the two groups were analyzed, and the combination parameters with best diagnostic performance were selected using the LDA method.ResultsOf the 45 patients with COVID-19 (35 moderate and 10 severe cases), 23 were male and 22 female, aged 16-62 years. The most common clinical symptoms were fever (89%) and dry cough (60%). As the disease progressed, WBC, Neu#, NLR, PLR, RDW-CV and RDW-SD parameters in the severe group were significantly higher than that in the moderate group (P<0.05); meanwhile, Lym#, Eos#, HFC%, RBC, HGB and HCT parameters in the severe group were significantly lower than that in the moderate group (P<0.05). For NLR, the AUC, the best cut-off value, the sensitivity and the specificity were 0.890, 13.39, 83.3% and 82.4% respectively, and for PLR, the AUC, the best cut-off, the sensitivity and the specificity were 0.842, 267.03, 83.3% and 74.0% respectively. The combined parameter NLR&RDW-SD had the best diagnostic efficiency (AUC was 0.938) and when the cut-off value was 1.046, the sensitivity and the specificity were 90.0% and 84.7% respectively, followed by the fitting parameter NLR&RDW-CV (AUC = 0.923). When the cut-off value was 0.62, the sensitivity and the specificity for distinguishing severe type from moderate cases of COVID-19 were 90.0% and 82.4% respectively.ConclusionsThe combined parameter NLR&RDW-SD is the best hematology index and can help clinicians to predict the severity of COVID-19 patients, and it can be used as a useful indicator to help prevent and control the epidemic.

scholarly journals Clinical Characteristics of Non-Pneumonia COVID-19 Adults in Shanghai, China

2020 ◽  
Author(s):  
Haiying Ji ◽  
Lijuan Hu ◽  
Tao Li ◽  
Linjing Gong ◽  
Xu Wu ◽  
...  
Keyword(s):  
Incubation Time ◽  
Clinical Characteristics ◽  
Clinical Symptoms ◽  
Diagnostic Classification ◽  
Test Results ◽  
Underlying Condition ◽  
Laboratory Test Results ◽  
Initial Symptoms ◽  
Local Residents ◽  
Taste Disorders

Abstract Background: Since December 2019, coronavirus disease 2019 (COVID-19) rapidly spread throughout the whole world , data have been needed on the clinical characteristics of the affected patients.Objectives: A total of 579 adult COVID-19 cases were enrolled in Shanghai from Jan 20 to Apr 15, 2020, in which 95 cases (16.41%) showed non-pneumonia on CT when confirmed. The characteristics of non-pneumonia cases have not been clearly described previously, and this might provide guidance to prevent and treatment of COVID-19.Method: We retrospectively collected the patient clinical dataset including demography, epidemiology, clinical manifestation, laboratory test results, diagnostic classification, treatment and clinical outcomes.Results: The average age of 95 COVID-19 cases was 31.45 ± 12.89 years old and 95.79% of them were less than 60 years old. They had mild clinical symptoms and/or laboratory abnormalities. 20 of the 95 cases occurred mild pneumonia during hospitalization, accompanied with lower lymphocyte counts, in which 60% cases were complicated with underlying condition and 15% cases were over 60 years old. All cases were cured. 16 of the 95 cases were local residents with clear epidemiological history and long incubation time, and mainly discovered as fever and respiratory symptoms. Other 79 cases were overseas imported, some had initial symptoms of diarrhea, smell or taste disorders and so on. They were mainly found at port of entry.Conclusions: Non-pneumonia COVID-19 predominantly occurred among young adults with mild clinical symptoms and possible long incubation time. The patients with underlying condition or at older age more likely developed mild pneumonia after diagnosis. Thereby, it is very important to pay attention to these patients and make reasonable diagnostic classification towards better prevention and treatment of COVID-19.

scholarly journals Abdominal Cross-sectional Imaging for Inpatients With Abnormal Liver Function Test Results

2001 ◽  
Vol 161 (4) ◽  
pp. 583 ◽  
Author(s):  
Jeffrey M. Rothschild ◽  
Ramin Khorasani ◽  
Stuart G. Silverman ◽  
Richard W. Hanson ◽  
Julie M. Fiskio ◽  
...  
Keyword(s):  
Liver Function ◽  
Liver Function Test ◽  
Abnormal Liver Function ◽  
Abnormal Liver Function Test ◽  
Test Results ◽  
Cross Sectional ◽  
Function Test ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

scholarly journals Hepatic encephalopathy. Clinical case

2021 ◽  
Vol 11 (5) ◽  
pp. 166-178
Author(s):  
Natalia Rafalska
Keyword(s):  
Hepatic Encephalopathy ◽  
Liver Function ◽  
Neurological Disorders ◽  
Clinical Case ◽  
Abnormal Liver Function ◽  
The West

Hepatic encephalopathy is a neuropsychiatric syndrome associated with abnormal liver function and portosystemic venous shunting. According to the West-Haven classification, depending on the degree of neurological disorders, there are minimal, I - IV stages of HE, which are characterized by a gradual progression of the disease. To date, the pathogenesis of HE is controversial.

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