scholarly journals Comparison of Use of Isoflurane or Sevoflurane for Anaesthesia Induced by Mask in Calves

2020 ◽  
Vol 48 ◽  
Author(s):  
Selvinaz Yakan ◽  
Ozgur Aksoy ◽  
Celal Sahin Ermutlu

Background: Inhalation anaesthesia is an effective and reliable general anaesthesia method for inactivity, analgesia, and unconsciousness in extensive surgical procedures. Although widely used, especially in small animals, there are very few studies investigated the reliability and superiority of inhalation anaesthesia in surgical procedures for ruminants. This study intended to evaluate the anaesthetic effects of isoflurane and sevoflurane in different surgical cases with endotracheal intubation following the induction of anaesthesia using a calve-specific facemask, which is not yet a routine option in cattle.Materials, Methods & Results: The study was conducted on 14 calves, from new-born up to 3 months-old, that undergoing various surgical operations. The animals were divided into isoflurane and sevoflurane groups, and each group contained 7 animals. In all cases, atropine (0.04 mg/kg was administered intramusculer as premedication before 15 min from anaesthesia induction. For induction, the anaesthetic agent was given at an inspiratory concentration of 3-5% in the isoflurane group and at an inspiratory concentration of 5 - 7% in the sevoflurane group during 5 min via mask at 15min after atropine administration. In both groups, endotracheal intubation was performed (about 1-3 min) after of general anaesthesia symptoms starting. At 5min after induction, anaesthesia was continued at 1.5 - 3% in the isoflurane group and at 2.5 - 4% in the sevoflurane group during operation. The animals were monitored during anaesthesia and,  anaesthetic effect, reaction of the calve, pronounced side effects, Heart Rate (HR), Systolic Arterial Blood Pressure (SABP), Diastolic Arterial Blood Pressure (DABP), Mean Arterial Blood Pressure (MABP), Respiration Rate (RR), Pulse Rate (PR), Arterial Oxygen Saturation (SpO2) were recorded at before anaesthesia, the premedication period, 5, 15, 30, 45, 60, 75 and 90min of anaesthesia. During anaesthesia, from the clinical parameters, mucosal capillary refilling time was evaluated by applying finger pressure to the oral mucosa. Mucous membrane color was determined by observing the oral mucosa. The time for palpebral reflex and swallowing reflex disappearance was measured and processed into individual forms. Anaesthesia induction and reanimation times were determined and recorded in the forms. After the operation, the return of the swallowing reflex and the time to stand up were recorded. During the operation, urination, defecation, salivation, vomiting, animal reactions, the shape and duration of the reamination period were recorded. In the isoflurane group anaesthesia induction was 3.71 ± 0.28 min, head movements started and came to the sterno- abdominal position at 4.57 ± 0.36 min, got up at 8.71 ± 0.42 min without assistance, meanwhile. In sevoflurane group, anaesthesia induction was 2.57 ± 0.20 min, head movements started and came to the sterno- abdominal position at 3.86 ± 0.40 min, the time to stand up was determined as 6.43 ± 0.29 min. During anaesthesia, HR, SABP, DABP, MABP, RR, PR, SpO2 findings were within physiological acceptable limits in 2 groups. In terms of indicators, there were no obvious differences in either group. The results revealed no significant difference between groups during anaesthesia.Discussion: The isoflurane and sevoflurane anaesthesia used in this study provided an adequate anaesthetic effect in calves characterized by adequate analgesia and muscle relaxation without any complications. The results of our study revealed that there was no significant difference between isoflurane and sevoflurane in calves. Both anaesthetic agents can be used safely for general anaesthesia in calves.

2016 ◽  
Vol 36 (1) ◽  
pp. 33-38
Author(s):  
Verônica B. Albuquerque ◽  
Marcelo A. Araújo ◽  
Alice R. Oliveira ◽  
Guilherme Cavalcanti ◽  
Rodrigo C. Leal ◽  
...  

Abstract: The aim of this study was to assess the cardiopulmonary effects, the onset time after the administration of a detomidine/ketamine combination, and the recovery from anesthesia of cougars (Puma concolor) anesthetized with detomidine/ketamine and isoflurane or sevoflurane for abdominal ultrasound imaging. Fourteen animals were randomly allocated into two experimental groups: GISO (n=7) and GSEVO (n=7). Chemical restraint was performed using 0.15mg/kg detomidine combined with 5mg/kg ketamine intramuscularly; anesthesia induction was achieved using 2mg/kg propofol intravenously and maintenance with isoflurane (GISO) or sevoflurane (GSEVO). The following parameters were assessed: heart rate, respiratory rate, systolic and diastolic arterial blood pressure, mean arterial blood pressure, oxyhemoglobin saturation, rectal temperature, central venous pressure, and end-tidal carbon dioxide. The time to sternal recumbency (TSR) and time to standing position (TSP) were also determined. There was not statistically significant difference for the cardiopulmonary variables or TSP whereas TSR was significantly shorter in GSEVO. The time to onset of anesthesia was 11.1±1.2 minutes and 11.3±1.8 minutes for GISO and GSEVO, respectively. The anesthesia of cougars with detomidine/ketamine and isoflurane or sevoflurane was conducted with safety, cardiopulmonary stability, and increased time to sternal recumbency in the GISO group.


2021 ◽  
Vol 6 (3) ◽  
pp. 104-111
Author(s):  
Urszula Kosciuczuk ◽  
Paulina Gluszynska ◽  
Inna Diemieszczyk ◽  
Aleksander Lukaszewicz ◽  
Krzysztof Bauer ◽  
...  

1996 ◽  
Vol 270 (3) ◽  
pp. H951-H956 ◽  
Author(s):  
S. W. Mittelstadt ◽  
L. B. Bell ◽  
K. P. O'Hagan ◽  
J. E. Sulentic ◽  
P. S. Clifford

The purpose of this study was to investigate the effects of the muscle chemoreflex on vascular conductance in innervated and denervated kidneys. During each experiment, six dogs ran at 10 km/h for 8-16 min, and the muscle chemoreflex was stimulated by reducing hindlimb blood flow (HLBF) (0%-74%) at 4-min intervals. Small reductions in HLBF did not cause changes in arterial blood pressure or renal vascular conductance. However, further reductions of HLBF caused increases in arterial blood pressure and decreases in renal vascular conductance. Decreases in renal vascular conductance occurred in the denervated kidneys when the HLBF was reduced below 1,500 +/- 215 ml/min and occurred in the innervated kidneys when HLBF was reduced below 1,402 +/- 161 ml/min. There was not a significant difference between the reductions in HLBF required to cause a decrease in vascular conductance in the innervated and denervated kidneys. These results demonstrate that reductions in HLBF cause decreases in renal vascular conductance, which are not dependent on renal sympathetic nerve activity.


2020 ◽  
Vol 267 (5) ◽  
pp. 1331-1339 ◽  
Author(s):  
Simon Fandler-Höfler ◽  
Stefan Heschl ◽  
Placido Argüelles-Delgado ◽  
Markus Kneihsl ◽  
Eva Hassler ◽  
...  

2003 ◽  
Vol 5 (5) ◽  
pp. 265-270 ◽  
Author(s):  
G.M. Mendes ◽  
A.L. Selmi ◽  
G.R. Barbudo-Selmi ◽  
B.T. Lins ◽  
J.P. Figueiredo

The purpose of this report was to evaluate the cardiorespiratory effects and efficacy of dexmedetomidine as a premedicant agent in cats undergoing ovariohysterectomy anaesthetized with propofol–sevoflurane. Cats were randomly divided into two groups of eight animals each. Dexmedetomidine (0.01 mg/kg) or 0.9% saline was administered intravenously (D and S, respectively). After 5 min, propofol was administered intravenously and anaesthesia was maintained with sevoflurane. Heart and respiratory rates, arterial blood pressure, oxygen saturation, rectal temperature and the amount of propofol needed for induction were measured. Premedication with dexmedetomidine reduced the requirement of propofol (6.7±3.8 mg/kg), but induced bradycardia, compared with the administration of saline (15.1±5.1 mg/kg). Recovery quality was significantly better in D but no significant difference in time to return of swallowing reflex was observed between groups (D=2.5±0.5 min;S=3.2±1.8 min). In conclusion, dexmedetomidine is a safe and effective agent for premedication in cats undergoing propofol–sevoflurane anaesthesia with minimal adverse effects.


1972 ◽  
Vol 42 (6) ◽  
pp. 685-700 ◽  
Author(s):  
A. Verniory ◽  
P. Potvliege ◽  
J. J. Van Geertruyden ◽  
P. Vereerstraeten ◽  
P. Kinnaert ◽  
...  

1. Plasma renin concentrations were determined in 1068 samples obtained in 113 patients in the end stage of chronic renal failure treated by repeated haemodialyses or by renal transplantation. 2. Patients with malignant nephroangiosclerosis have a very high concentration of plasma renin; this differentiates them from other disease groups, where renin concentration is sometimes normal and sometimes elevated; there is no significant difference between the glomerulonephritis and pyelonephritis groups. 3. There is a weak but significant correlation between plasma renin concentration and arterial blood pressure. In the terminal stage of chronic renal insufficiency, blood pressure appears to be controlled by other quantitatively more important factors. However, the hypertension of some cases, characterized by high concentrations of plasma renin, can be controlled only by bilateral nephrectomy. 4. There is an inverse and highly significant correlation between plasma renin and sodium concentrations. This is also the case in transplanted patients where an inverse correlation also exists between plasma renin concentration and daily urinary output of sodium. 5. The juxtaglomerular granulation index correlates positively with the plasma renin concentration. 6. In terminal renal failure the kidney retains its capacity to secrete renin as a response to acute haemorrhage or other stimuli. 7. Renin is present in the blood of anephric patients and its concentration is not correlated either with the patient's sex or with the time elapsed after binephrectomy. 8. During rejection episodes in transplanted patients a rise of plasma renin concentration is frequently but not invariably observed. Elevation of plasma renin concentration is evident in very acute rejection crises.


1972 ◽  
Vol 50 (6) ◽  
pp. 545-553 ◽  
Author(s):  
A. J. Lewis ◽  
P. Eyre

The cardiorespiratory responses to histamine, 5-hydroxytryptamine, and compound 48/80 have been examined in the calf. The simultaneous measurement of whole blood histamine and plasma 5-hydroxytryptamine during compound 48/80 infusion showed significantly elevated levels that followed a biphasic pattern. However, mast cell changes in the sites examined were minimal and there was no significant difference in histamine concentrations in tissues examined. Marked systemic effects were observed and included an initial rise in femoral arterial blood pressure which was later followed by a terminal hypotension and death. Pulmonary arterial blood pressure and venous pressure were both elevated and dyspnoeic respiration was also evident. A combination of mepyramine and methysergide inhibited the toxicity of compound 48/80 which suggested that histamine and 5-hydroxytryptamine played a major role in the toxic response to this substance in the calf.


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