scholarly journals Aetiology and Clinical Profile of Giant Left Atrium -- An Observational Study.

2021 ◽  
Author(s):  
AKM Monwarul Islam ◽  
A.A.S. Majumder ◽  
Shovan Rahman ◽  
Kaniz Ananya ◽  
Tanveer Ahmad ◽  
...  
Keyword(s):  
Heart Disease ◽  
Observational Study ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Left Atrial ◽  
Tertiary Care ◽  
Volume Index ◽  
Giant Left Atrium ◽  
Rheumatic Heart

Background: The predominant cause of giant left atrium (GLA) is rheumatic mitral valvular disease. GLA is commonly defined echocardiographically by measuring the left atrial diameter (LAD). In the context of changing epidemiology of rheumatic heart disease (RHD) globally, and introduction of left atrial volume index (LAVI), the aetiology of GLA and utility of LAVI for defining GLA may be necessary. Methods: The prospective observational study was carried out at a dedicated tertiary care cardiac centre of a developing country to know the aetiology and clinical pattern of GLA over 8 years. GLA was defined echocardiographically as a left atrium (LA) having a diameter ≥80 mm in the left parasternal long-axis view. Follow-up was made over the telephone. Results: Thirty cases of GLA were diagnosed over 8 years from 2013 to 2021. Twenty two were due to rheumatic heart disease (RHD), 7 due to MVP, and 1 due to flail anterior mitral leaflet. Mean LAD was 92.13 ± 16.72 mm, and the mean LAVI was 288.77 ± 134.40 ml/m2. LA thrombus was present in 5 patients, 6 had spontaneous echo contrast (SEC) in LA, 2 had both LA thrombus and SEC. Mean follow-up was 0.99 ± 1.06 years. Out of 15 patients, 5 died, while 10 were alive. Mean survival was 1.8 ± 1.17 years, ranging from less than 1 year to 4 years. Conclusion: RHD continues to be the predominant cause of GLA; however, MVP is also important. The cut-off value of LAVI for defining GLA needs further study.

Giant Left Atrium in Rheumatic Heart Disease: The Classic Signs of Left Atrial Enlargement

2013 ◽  
Vol 44 (6) ◽  
pp. e393-e394 ◽  
Author(s):  
Jeffrey Forris Beecham Chick ◽  
Scott E. Sheehan ◽  
Jared D. Miller ◽  
Ryan J. Bair ◽  
Rachna Madan
Keyword(s):  
Heart Disease ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement ◽  
Giant Left Atrium ◽  
Rheumatic Heart

scholarly journals Giant Left Atrium in Rheumatic Heart Disease

1971 ◽  
Vol 174 (2) ◽  
pp. 194-201 ◽  
Author(s):  
J. PLASCHKES ◽  
J. B. BORMAN ◽  
G. MERIN ◽  
H. MILWIDSKY
Keyword(s):  
Heart Disease ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Giant Left Atrium ◽  
Rheumatic Heart

Giant left atrium in a woman with mitral prosthetic valve malfunction and history of rheumatic heart disease

2009 ◽  
Vol 4 (5) ◽  
pp. 435-437
Author(s):  
Gaspare Parrinello ◽  
Daniele Torres ◽  
Salvatore Paterna ◽  
Manuela Mezzero ◽  
Pietro Di Pasquale ◽  
...  
Keyword(s):  
Heart Disease ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Prosthetic Valve ◽  
History Of ◽  
Giant Left Atrium ◽  
Valve Malfunction ◽  
Rheumatic Heart

scholarly journals Giant Left Atrium in Triple Rheumatic Heart Disease

2018 ◽  
Vol 13 ◽  
Author(s):  
Gëzim Berisha ◽  
Edmond Haliti ◽  
Gani Bajraktari
Keyword(s):  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Mitral Valve ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Heart Team ◽  
Giant Left Atrium ◽  
Rheumatic Heart

The giant left atrium (GLA) is a rare condition, commonly associated with rheumatic mitral valve disease, and very rarely with non rheumatic heart disease (nRHD). The triple valvular heart disease with involved mitral, aortic and tricuspid valves is quite uncommon. A 47 year female patient with a past medical history of rheumatic heart disease (RHD) and known severe mitral stenosis was with severe breathlessness (NYHA class IV). She had undergone mitral valve commissurotomy and tricuspid valve annuloplasty 12 years previously.  Transthoracic echocardiography revealed a giant left atrium, moderate to severe mitral valve restenosis, severe mitral regurgitation, moderate aortic regurgitation and severe tricuspid regurgitation, associated with severe secondary pulmonary hypertension and a markedly dilated right heart chambers. The patient was considered inoperable by the heart team, because of advanced pulmonary hypertension predicting a very high risk for open heart surgery. The final treatment decision was a difficult and complex issue.

scholarly journals Largest giant left atrium in rheumatic heart disease

2020 ◽  
Author(s):  
Bhagya Narayan Pandit ◽  
Puneet Aggarwal ◽  
Siva Subramaniyan ◽  
Jaskaran Singh Gujral ◽  
Ranjit Kumar Nath
Keyword(s):  
Heart Disease ◽  
Left Atrium ◽  
Rheumatic Heart Disease ◽  
Giant Left Atrium ◽  
Rheumatic Heart

225 Rheumatic heart disease in Timor Leste school students (RHD-TL) follow-up study: assessment of secondary prophylaxis and outcomes in Timor Leste

2020 ◽  
Vol 41 (Supplement_1) ◽  
Author(s):  
A Horton ◽  
B Remenyi ◽  
K Davis ◽  
N Mock ◽  
E Paratz ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Secondary Prophylaxis ◽  
Penicillin G ◽  
School Students ◽  
Borderline Cases ◽  
Follow Up Study ◽  
Timor Leste ◽  
Rheumatic Heart

Abstract Background The Rheumatic Heart disease in Timor Leste school students (RHD-TL) study identified Timor Leste as having some of the highest rates of definite rheumatic heart disease (RHD) in the world. The RHD-TL follow-up study aimed to assess the delivery and outcomes of the secondary prophylaxis program in known patients with echocardiographic screen detected definite and borderline RHD. Methods School-students in Timor Leste where reassessed over a 3-year period since the initial study in 2016. Prospective assessments included adherence to secondary prophylaxis, complications of prophylaxis, follow-up clinical assessment and serial echocardiography. Of the 48 patients, 25 Definite and 23 Borderline, 38 (79%) of all patients, and 92% of definite RHD cases have had one or more follow-up assessments including full datasets for adherence, recurrence rates and progression of disease. Follow-up is provided by the volunteer paediatric cardiology team and rheumatic heart disease team of two NGOs in collaboration with local clinics. Results The median duration of follow-up of the 38 patients was of 1.6 years. The median age was 13 years (range 8-22) and 75% were female. Adherence rates in patients with definite RHD was on average greater than 95% during the follow-up period. Of the 23 patients with mild or moderate RHD one case with documented acute rheumatic fever (ARF) recurrence progressed whilst 8 cases improved on benzathine-penicillin G (BPG) therapy. There was no progression of the 6 borderline cases who were not prescribed BPG. Out of the 9 borderline cases in whom BPG was prescribed, one, with 67% adherence, had a documented episode of ARF leading to echocardiographic progression and moderate definite RHD. Conclusion This was the first follow-up study to look at disease natural history, both in treated and untreated groups, in Timor-Leste and brought practical insights into the efficacy of the Timor Leste RHD monitoring and prophylaxis programs. Its ongoing project will enable advocacy and quality assessment for the program as it expands. Abstract 225 Figure 1.

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