Prevalence and follow‐up of subclinical rheumatic heart disease among asymptomatic school children in a north‐western district of India based on the World Heart Federation echocardiographic criteria

2021 ◽  
Author(s):  
Dinesh Choudhary ◽  
Sadik Raja Panwar ◽  
Bal Kishan Gupta ◽  
Raja Babu Panwar ◽  
Rajeev Gupta ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
The World ◽  
North Western ◽  
Rheumatic Heart

HIGH PREVALENCE OF RHEUMATIC HEART DISEASE IN 2603 SCHOOL CHILDREN IN NORTH-WEST INDIA WITH 6 MONTHS AND 2 YEARS FOLLOW-UP: AN ECHOCARDIOGRAPHIC SURVEY

2019 ◽  
Vol 73 (9) ◽  
pp. 2025
Author(s):  
Raja Babu Panwar ◽  
Bal Kishan Gupta ◽  
Arvind Kumar Sharma ◽  
Dinesh Choudhary ◽  
Sadik Panwar ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
North West ◽  
High Prevalence ◽  
Rheumatic Heart

scholarly journals Prevalence of Rheumatic Fever and Rheumatic Heart Disease in School Children of Bharateswari Homes of Bangladesh

2014 ◽  
Vol 6 (2) ◽  
pp. 103-106 ◽  
Author(s):  
AAS Majumder ◽  
MS Flora ◽  
AKMM Islam ◽  
M Shahidullah ◽  
MA Zafar ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
Health Care Services ◽  
Care Services ◽  
High Incidence ◽  
The World ◽  
School Survey ◽  
Rheumatic Heart

Background: Rheumatic fever (RF) and rheumatic heart disease (RHD) continue to affect millions of people around the world, including Bangladesh. Children and adolescents are especially susceptible to this disease. Classical risk factors, i.e. poverty, overcrowding, ignorance and insufficient health care services are responsible for the high incidence and prevalence of these diseases. To assess the prevalence of RF and RHD among children, a school survey was conducted in Bharateswari Homes, in the district of Tangail, Bangladesh. Methods: A total of 947 students were examined. Revised Jones’ criteria (1992), and clinical examination were used for the diagnosis of RF and RHD. Results: Four cases of RF/RHD were found giving the prevalence of 4.22/1000. This is lower than the prevalence reported in eighties, but is consistent with those found in nineties. Conclusion: Among the school children, there is a declining trend in the prevalence of RF/RHD. DOI: http://dx.doi.org/10.3329/cardio.v6i2.18348 Cardiovasc. j. 2014; 6(2): 103-106

225 Rheumatic heart disease in Timor Leste school students (RHD-TL) follow-up study: assessment of secondary prophylaxis and outcomes in Timor Leste

2020 ◽  
Vol 41 (Supplement_1) ◽  
Author(s):  
A Horton ◽  
B Remenyi ◽  
K Davis ◽  
N Mock ◽  
E Paratz ◽  
...  
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Secondary Prophylaxis ◽  
Penicillin G ◽  
School Students ◽  
Borderline Cases ◽  
Follow Up Study ◽  
Timor Leste ◽  
Rheumatic Heart

Abstract Background The Rheumatic Heart disease in Timor Leste school students (RHD-TL) study identified Timor Leste as having some of the highest rates of definite rheumatic heart disease (RHD) in the world. The RHD-TL follow-up study aimed to assess the delivery and outcomes of the secondary prophylaxis program in known patients with echocardiographic screen detected definite and borderline RHD. Methods School-students in Timor Leste where reassessed over a 3-year period since the initial study in 2016. Prospective assessments included adherence to secondary prophylaxis, complications of prophylaxis, follow-up clinical assessment and serial echocardiography. Of the 48 patients, 25 Definite and 23 Borderline, 38 (79%) of all patients, and 92% of definite RHD cases have had one or more follow-up assessments including full datasets for adherence, recurrence rates and progression of disease. Follow-up is provided by the volunteer paediatric cardiology team and rheumatic heart disease team of two NGOs in collaboration with local clinics. Results The median duration of follow-up of the 38 patients was of 1.6 years. The median age was 13 years (range 8-22) and 75% were female. Adherence rates in patients with definite RHD was on average greater than 95% during the follow-up period. Of the 23 patients with mild or moderate RHD one case with documented acute rheumatic fever (ARF) recurrence progressed whilst 8 cases improved on benzathine-penicillin G (BPG) therapy. There was no progression of the 6 borderline cases who were not prescribed BPG. Out of the 9 borderline cases in whom BPG was prescribed, one, with 67% adherence, had a documented episode of ARF leading to echocardiographic progression and moderate definite RHD. Conclusion This was the first follow-up study to look at disease natural history, both in treated and untreated groups, in Timor-Leste and brought practical insights into the efficacy of the Timor Leste RHD monitoring and prophylaxis programs. Its ongoing project will enable advocacy and quality assessment for the program as it expands. Abstract 225 Figure 1.

High Prevalence of Rheumatic Heart Disease Detected by Echocardiography in School Children

2010 ◽  
Vol 27 (4) ◽  
pp. 448-453 ◽  
Author(s):  
Maneesha Bhaya ◽  
Sadik Panwar ◽  
Rajesh Beniwal ◽  
Raja Babu Panwar
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
High Prevalence ◽  
Rheumatic Heart

scholarly journals Prevalence of rheumatic heart disease among school children in East Africa: a systematic review and meta-analysis

2021 ◽  
Vol 38 ◽  
Author(s):  
Melaku Bimerew ◽  
Biruk Beletew ◽  
Addisu Getie ◽  
Adam Wondmieneh ◽  
Getnet Gedefaw ◽  
...  
Keyword(s):  
Systematic Review ◽  
Heart Disease ◽  
East Africa ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
Meta Analysis ◽  
Rheumatic Heart

scholarly journals Rheumatic heart disease in school children in Samoa

1999 ◽  
Vol 81 (4) ◽  
pp. 372-372 ◽  
Author(s):  
A. C STEER ◽  
J. ADAMS ◽  
J. CARLIN ◽  
T. NOLAN ◽  
F. SHANN
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
School Children ◽  
Rheumatic Heart

scholarly journals Validation of a simplified score for predicting latent rheumatic heart disease progression using a prospective cohort of Brazilian schoolchildren

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e036827 ◽  
Author(s):  
Bárbara Martins Bechtlufft ◽  
Bruno Ramos Nascimento ◽  
Craig Sable ◽  
Clara Leal Fraga ◽  
Márcia Melo Barbosa ◽  
...  
Keyword(s):  
Heart Disease ◽  
Public Schools ◽  
Rheumatic Heart Disease ◽  
Heart Diseases ◽  
Diagnostic Category ◽  
Secondary Outcome ◽  
Unfavourable Outcome ◽  
History Of ◽  
Rheumatic Heart

ObjectivesEchocardiographic (echo) screening is an important tool to estimate rheumatic heart disease (RHD) prevalence, but the natural history of screen-detected RHD remains unclear. The PROVAR+ (Programa de RastreamentO da VAlvopatia Reumática) study, which uses non-experts, telemedicine and portable echo, pioneered RHD screening in Brazil. We aimed to assess the mid-term evolution of Brazilian schoolchildren (5–18 years) with echocardiography-detected subclinical RHD and to assess the performance of a simplified score consisting of five components of the World Heart Federation criteria, as a predictor of unfavourable echo outcomes.SettingPublic schools of underserved areas and private schools in Minas Gerais, southeast Brazil.ParticipantsA total of 197 patients (170 borderline and 27 definite RHD) with follow-up of 29±9 months were included. Median age was 14 (12–16) years, and 130 (66%) were woman. Only four patients in the definite group were regularly receiving penicillin.Primary and secondary outcome measuresUnfavourable outcome was based on the 2-year follow-up echo, defined as worsening diagnostic category, remaining with mild definite RHD or development/worsening of valve regurgitation/stenosis.ResultsAmong patients with borderline RHD, 29 (17.1%) progressed to definite, 49 (28.8%) remained stable, 86 (50.6%) regressed to normal and 6 (3.5%) were reclassified as other heart diseases. Among those with definite RHD, 13 (48.1%) remained in the category, while 5 (18.5%) regressed to borderline, 5 (18.5%) regressed to normal and 4 (14.8%) were reclassified as other heart diseases. The simplified echo score was a significant predictor of RHD unfavourable outcome (HR 1.197, 95% CI 1.098 to 1.305, p<0.001).ConclusionThe simple risk score provided an accurate prediction of RHD status at 2-year follow-up, showing a good performance in Brazilian schoolchildren, with a potential value for risk stratification and monitoring of echocardiography-detected RHD.

scholarly journals Platelet-leukocyte aggregate is associated with adverse events after surgical intervention for rheumatic heart disease

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chaonan Liu ◽  
Yang Yang ◽  
Lei Du ◽  
Si Chen ◽  
Jie Zhang ◽  
...  
Keyword(s):  
Heart Disease ◽  
Adverse Events ◽  
Rheumatic Heart Disease ◽  
Surgical Intervention ◽  
Vascular Lesions ◽  
Kaplan Meier ◽  
Rheumatic Valve Disease ◽  
Cox Proportional Hazard Regression ◽  
Rheumatic Heart

Abstract Platelet-leukocyte aggregate (PLA) is implicated in the etiology of both vascular lesions and cardiovascular events. This prospective cohort study aimed to examine the prognostic value of PLA for major adverse cardiac and cerebrovascular events (MACCE) and perioperative adverse events (AEs) in patients with rheumatic heart disease undergoing surgical intervention by Cox proportional hazard regression and logistic regression. A total of 244 patients were included, of whom 7 were lost to follow-up. Among the analyzed 237 subjects who completed 3-year follow-up, 30 experienced MACCE and 38 experienced perioperative AEs. Preoperative PLA was higher in subjects who developed MACCE (13.32%) than in those who did not (8.69%, p = 0.040). In multivariate regression, elevated PLA was associated with increased MACCE (hazard ratio 1.51 for each quartile, 95% CI 1.07–2.13; p = 0.020), and perioperative AEs (odds ratio 1.61, 95% CI 1.14–2.26; p = 0.007). The optimal PLA cut-off for predicting MACCE was 6.8%. Subjects with PLA > 6.8% had a higher prevalence of MACCE (17.1% vs. 5.5%, p = 0.009) and perioperative AEs (19.9% vs. 8.6%, p = 0.018). Kaplan-Meier analysis showed shorter MACCE-free survival in patients with PLA > 6.8% (p = 0.007, log rank). Elevated preoperative PLA is associated with increased MACCE and perioperative AEs in patients with rheumatic valve disease undergoing surgical intervention.

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