scholarly journals Multiple endocrine disorders manifested as gynecomastia in a patient with renal pelvis cancer

Author(s):  
Vladimir Bilim ◽  
Senji Hoshi

A 95-year-old man was diagnosed with left pelvis cancer which presented with rapid tumor growth, multiple metastases, and bilateral tender gynecomastia. Elevated serum human chorionic gonadotropin(hCG), prolactin, estradiol, and progesterone were detected. The patient’s condition rapidly deteriorated and he passed away.

2007 ◽  
Vol 114 (2) ◽  
pp. 94-102 ◽  
Author(s):  
Ning Yu ◽  
Wei Xu ◽  
Zhenggang Jiang ◽  
Qinghua Cao ◽  
Yiwei Chu ◽  
...  

1994 ◽  
Vol 170 (4) ◽  
pp. 1135-1138 ◽  
Author(s):  
Chaur-Dong Hsu ◽  
Daniel W. Chan ◽  
Brian Iriye ◽  
Timothy R.B. Johnson ◽  
Shih-Fen Hong ◽  
...  

Endocrinology ◽  
2002 ◽  
Vol 143 (8) ◽  
pp. 3114-3121 ◽  
Author(s):  
Ulrich Pfeffer ◽  
Davide Bisacchi ◽  
Monica Morini ◽  
Roberto Benelli ◽  
Simona Minghelli ◽  
...  

2007 ◽  
Vol 62 (10) ◽  
pp. 675-679 ◽  
Author(s):  
Ezgi Demirtas ◽  
Srinivasan Krishnamurthy ◽  
Togas Tulandi

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Bernd C. Schmid ◽  
Aimee Reilly ◽  
Martin K. Oehler

Human chorionic gonadotropin (hCG) is useful in evaluating and monitoring early pregnancy as well as trophoblastic disease. Here we describe the management of women with elevated serum human chorionic gonadotropin in a case of a 51-year-old female who was unsuccessfully treated for ectopic pregnancy. She was subsequently diagnosed with pituitary hCG production, which should be considered as differential diagnosis before treatment is initiated.


1998 ◽  
Vol 5 (1) ◽  
pp. E8 ◽  
Author(s):  
Tsutomu Kato ◽  
Yutaka Sawamura ◽  
Mitsuhiro Tada ◽  
Jun-ichi Murata ◽  
Hiroshi Abe ◽  
...  

Although neurohypophyseal germinoma is known be a common initial symptom in cases of diabetes insipidus (DI), its radiological detection may take months or years even by a high-resolution magnetic resonance (MR) imaging. The term “occult neurohypophyseal germinoma” denotes such cases, but its clinical picture remains obscure. Of seven patients with neurohypophyseal germinoma presenting with DI during the last 5 years, three patients showed no evidence of tumor at the onset of DI and were treated as “idiopathic” DI. Neurohypophyseal germinoma was eventually diagnosed in these three patients as the tumor became evident on sequential MR imaging studies and the patients were successfully treated with chemotherapy and radiation therapy. To delineate the clinical features of the occult neurohypophyseal germinoma, the authors analyzed endocrinological aspects and MR images in these patients and compared them with those in two patients with true idiopathic DI and four patients with overt neurohypophyseal germinoma and DI. Nine previously reported cases in the literature were reviewed. During the stage at which the germinoma gave no notable change on MR images, patients often displayed anterior pituitary dysfunction, particularly growth hormone (GH) deficiency, or an elevation of serum or cerebrospinal fluid human chorionic gonadotropin-beta. Preceding the appearance of an obvious tumor mass, a slight swelling of the pituitary stalk with loss of normal hyperintensity of the posterior pituitary lobe was a common finding on MR imaging. Central DI associated either with an enlarged stalk, decreased GH secretion, or an elevated serum human chorionic gonadotropin-beta should prompt the diagnosis of an occult germinoma.


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