scholarly journals Correlation between comorbidity and quality of life in the elderly cancer patients treated with chemotherapy: An ongoing study

2002 ◽  
Vol 10 (3) ◽  
pp. 146-146
Author(s):  
Svetlana Jezdic ◽  
Zorica Nikolic-Tomasevic ◽  
Ivan Popov ◽  
Davorin Radosavljevic
2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23013-e23013
Author(s):  
Sanketh Kotne ◽  
Bharadwaj Ponnada ◽  
Arun Philip ◽  
Pavithran Keechilat

e23013 Background: Treatment of cancer in elderly is challenging. Majority of the elderly cancer patients are offered chemotherapy based on their performance scale and geriatric assessment tools are not routinely employed in clinical practice as they are time consuming and cumbersome. Aim: The primary objective was to estimate the incidence of chemotherapy related adverse events in newly diagnosed elderly cancer patients above 65 years of age treated at a tertiary cancer institute in southern India. The secondary objective was to predict and assess the factors associated with chemotherapy related toxicities in the elderly patients using the Cancer and Aging Research Group's (CARG) scoring tool and to study the quality of life and to assess the nutritional status and the mental status in elderly cancer patients above 65 years of age. Methods: A prospective cross-sectional study was done among 179 patients with age ≥ 65 years, a solid organ cancer (any type or stage) from February 2017 to August 2018. Prechemotherapy comprehensive geriatric assessment (CGA) with Older People’s Quality of Life Questionnaire (OPQOL-35), Mini Nutritional assessment (MNA) and Folstein’s Mini Mental status examination (MMSE) was done at baseline, 2 months and 6 months. CARG tool was used to predict the risk of chemotherapy toxicity with the standard and modified dose. Results: The mean age was 68.53 years. Majority of the patients had breast cancer 29.60%. The proportion of lung cancer, prostate cancer, stomach cancer, colorectal and ovarian cancers were 21.80%,10.60%, 9.50%, 14.5% and 7.30% respectively. Other cancers were seen in 5 patients (2.79%). 40 (22.30%) patients had received anthracycline based chemotherapy. 143 (79.90%) had received standard dosing chemotherapy.118 (65.90%) & 125 (69.80%) out of 179 patients had developed hematological toxicities and non- hematological toxicities respectively. According to the ROC curve for the CARG tool risk of toxicity with standard & modified dosing and hematological & non- hematological toxicities, the accuracy of the test is 60.89% indicating its poor predictive validity. There is a decline in the CGA at 2 months follow-up, but there was an improvement after assessment at 6 months. Conclusions: Comprehensive geriatric assessment at base line is required to adequately analyse patient’s risk of chemotherapy related toxicities. In our study, the patients have tolerated the chemotherapy well in spite of receiving standard dosing.


2021 ◽  
Vol 4 (2) ◽  
pp. 634-642
Author(s):  
Nurlina Nurlina ◽  
Yuliana Syam ◽  
Ariyanti Saleh

This study aims to determine the effectiveness of music therapy in reducing anxiety in cancer patients. The research method is a literature review using five databases, namely PubMed, ProQuest, Science Direct, Clinicalkey, and Google Scholar, using keywords based on PICO. The results showed that the five articles analyzed all articles reported that music therapy effectively reduced anxiety in cancer patients. Music has psychological, physical, social, and spiritual effects that can increase support for cancer patient care, improve mood, and improve the quality of life of cancer patients to provide nursing interventions to reduce anxiety. In conclusion, music therapy is an effective therapy to reduce anxiety from children, adults to the elderly.   Keywords: Cancer, Anxiety, Music Therapy


2012 ◽  
Vol 42 (8) ◽  
pp. 704-710 ◽  
Author(s):  
T. Akechi ◽  
T. Okuyama ◽  
M. Uchida ◽  
T. Nakaguchi ◽  
Y. Ito ◽  
...  

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. e19532-e19532
Author(s):  
C. Blanc-Bisson ◽  
M. Fonck ◽  
S. Mathoulin-Pelissier ◽  
C. Mertens ◽  
V. Brouste ◽  
...  

2001 ◽  
Vol 12 ◽  
pp. S49-S52 ◽  
Author(s):  
L. Repetto ◽  
G. Ausili-Cefaro ◽  
C. Gallo ◽  
A. Rossi ◽  
L. Manzione

2006 ◽  
Vol 133 (5) ◽  
pp. 279-286 ◽  
Author(s):  
Ulrich Wedding ◽  
Bernd Röhrig ◽  
Ludger Pientka ◽  
Klaus Höffken

2019 ◽  
Vol 26 (4) ◽  
pp. 418-426
Author(s):  
Sevinç Kutlutürkan ◽  
Elif Sözeri Öztürk ◽  
Sultan Böke Erdoğan ◽  
Özlem İyimaya ◽  
Figen Bay ◽  
...  

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Tatiane Correia Rios ◽  
Lucivalda Pereira Magalhães de Oliveira ◽  
Maria Lúcia Varjão da Costa ◽  
Ramona Souza da Silva Baqueiro Boulhosa ◽  
Anna Karla Carneiro Roriz ◽  
...  

Abstract Rationale Quality of Life (QoL) is impaired in cancer, and the elderly are particularly vulnerable to malnutrition. A diagnosis of cancer in elderly patients further exacerbates risks of negative health outcomes. Here we investigated associations between QoL and nutritional status in a sample population of mostly socially deprived elderly cancer patients. Method 432 cancer patients were recruited for this cross-sectional study at point of admission to a tertiary referral hospital for cancer treatment. Patient-generated subjective global assessment (PG-SGA) assessed nutritional status. Functional assessment of cancer therapy- general (FACT-G) quantified QoL. Relationship between PG-SGA and QoL was assessed by Spearman correlation. PG-SGA outcomes were compared against FACT-G scores employing Mann–Whitney test. Bivariate Linear Regression Model was employed to investigate influences of sociodemographic, clinical and nutritional status upon QoL. Results 37.5% of participants were malnourished or at risk. 39% were illiterate and 54.6% had family income lower than minimum wage. Malnourished patients showed lower FACT-G scores (76.8 vs. 84.7; p = 0.000). Poor nutritional diagnosis was inversely correlated with all QoL domains. Bivariate regression analysis showed that lower PG-SGA scores (βo =  − 1.00; p = 0.000) contributed to FACT-G score deterioration, the male gender showed better QoL scores, and other clinical and sociodemographic variables did not show relationship. Conclusion Poorer nutritional status was significantly associated with worsened physical, social, emotional and functional well-being QoL domains in elderly cancer patients. Poorer nutritional status is an independent risk factor for worsened QoL. Future policies aimed at particularly vulnerable populations may improve QoL and health outcomes.


Author(s):  
Maria Lavdaniti ◽  
Sofia Zyga ◽  
Eugenia Vlachou ◽  
Despina Sapountzi-Krepia

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