scholarly journals Predictive functional control of temperature in a pharmaceutical hybrid nonlinear batch reactor

2013 ◽  
Vol 19 (4) ◽  
pp. 573-582 ◽  
Author(s):  
Simon Stampar ◽  
Sasa Sokolic ◽  
Gorazd Karer
Keyword(s):  
Temperature Control ◽  
Control Algorithm ◽  
Batch Reactor ◽  
Pharmaceutical Product ◽  
Control Law ◽  
Batch Reactors ◽  
Heating And Cooling ◽  
Pharmaceutical Substances ◽  
Functional Control

These days, in times of recession, we are forced by competitiveness and the optimization of production to lower the costs of the temperature control in pharmaceutical batch reactors and increase the quantity and quality of the produced pharmaceutical product (active pharmaceutical substances). Therefore, a control algorithm is needed which provides us rapid and precise temperature control. This paper deals with the development of a control algorithm, where two predictive functional controllers are connected in a cascade for heating and cooling the content of the hybrid batch reactor. The algorithm has to be designed to cope with the constraints and the mixed discrete and continuous nature of the process of heating and cooling. The main goal of the control law is to achieve rapid and exact tracking of the reference temperature, good disturbance rejection and, in particular, a small number of heating and cooling medium switchings. The simulation results of the proposed algorithm give us much better performance compared to a conventional cascade PI algorithm.

scholarly journals Advanced The Quality of Temperature Control of Batch Reactor using The Hybrid Fuzzy Controller

2020 ◽  
Vol 7 (11) ◽  
pp. 1-6
Author(s):  
Nguyen Duc Dien ◽  
Tran Ngoc Son ◽  
Roan Van Hoa ◽  
Vu Viet Thong ◽  
Pham Van Minh
Keyword(s):  
Temperature Control ◽  
Fuzzy Controller ◽  
Batch Reactor

scholarly journals Methodology of Supervision by Analysis of Thermal Flux for Thermal Conduction of a Batch Chemical Reactor Equipped with a Monofluid Heating/Cooling System

2012 ◽  
Vol 2012 ◽  
pp. 1-10
Author(s):  
Ghania Henini ◽  
Fatiha Souahi ◽  
Ykhlef Laidani
Keyword(s):  
Thermal Conduction ◽  
Cooling System ◽  
Batch Reactor ◽  
Thermal Flux ◽  
Exothermic Reaction ◽  
Chemical Reactor ◽  
Thermal Control ◽  
Ride Quality ◽  
Heating And Cooling

We present the thermal behavior of a batch reactor to jacket equipped with a monofluid heating/cooling system. Heating and cooling are provided respectively by an electrical resistance and two plate heat exchangers. The control of the temperature of the reaction is based on the supervision system. This strategy of management of the thermal devices is based on the usage of the thermal flux as manipulated variable. The modulation of the monofluid temperature by acting on the heating power or on the opening degrees of an air-to-open valve that delivers the monofluid to heat exchanger. The study shows that the application of this method for the conduct of the pilot reactor gives good results in simulation and that taking into account the dynamics of the various apparatuses greatly improves ride quality of conduct. In addition thermal control of an exothermic reaction (mononitration) shows that the consideration of heat generated in the model representation improve the results by elimination any overshooting of the set-point temperature.

A New Type of Proportion Cycle Temperature Control Algorithm

2013 ◽  
Vol 411-414 ◽  
pp. 1851-1854
Author(s):  
Ai Xiang He ◽  
Hai Ning Zhang ◽  
Meng Ke Zhang
Keyword(s):  
Temperature Control ◽  
Control Algorithm ◽  
Environmental Temperature ◽  
Control Effect ◽  
Heater Power ◽  
Heating And Cooling ◽  
New Type ◽  
Temperature Constant ◽  
Short Time ◽  
Cycle Temperature

A new type of proportion cycle temperature control algorithm is proposed in this paper. Controller can automatically identify temperature constant related to the heater power, combined with the real time environmental temperature change, dynamically modify the heating and cooling time, controlled volatility in setting temperature range.When the mutant short time ambient temperature occurs, it can make rapid response, so as to achieve better control effect.

Design of Water Heating and Temperature Control System Based on STC89C52

2015 ◽  
Vol 734 ◽  
pp. 255-259
Author(s):  
Ting Wang ◽  
Hao Wang
Keyword(s):  
Temperature Control ◽  
Control Algorithm ◽  
Intelligent System ◽  
Temperature Control System ◽  
Single Chip ◽  
Single Chip Microcomputer ◽  
Whole Process ◽  
Heating And Cooling ◽  
Design Requirements ◽  
Cooling Function

An intelligent system for water temperature control is designed in this paper based on STC89C52 single-chip microcomputer, in which temperature sensor DS18B20 is used to collect temperature data. This system adopts successive approximant algorithm and incremental PID control algorithm to change PWM pulse outputted by single-chip microcomputer and thus can realize heating and cooling function within a range between 30 °C and 100 °C as well as automatic control on constant temperature randomly set in the whole process. Result of experiments and tests indicated that this system can function stably, which can realize satisfactory control result and meet design requirements.

scholarly journals Development of a Simulation Model for Controlling and Improving the Productivity of Batch Reactors

2013 ◽  
Vol 15 (1) ◽  
pp. 78-87 ◽  
Author(s):  
Ghania Henini ◽  
Fatiha Souahi ◽  
Ykhlef Laidani
Keyword(s):  
Simulation Model ◽  
Cooling System ◽  
Batch Reactor ◽  
Fluid Flows ◽  
Batch Reactors ◽  
Unsteady State ◽  
Constant Flow Rate ◽  
Heating And Cooling ◽  
Dynamic Simulator ◽  
The Heat Balance

This paper describes the development of a dynamic simulator model for a jacketed batch reactor equipped with a mono-fluid heating/cooling system. The Mono-fluid flows at constant flow-rate through the jacketed reactor. The heating and cooling are assured respectively by electrical resistance and two plate heat exchangers. A detailed description of the equations leading to the development of simulation model is presented. The model is based on writing the equations of the mass balance and the heat balance for the reactor and the thermal loop in unsteady state. To validate the simulation model, we first studied the thermal behavior of the reaction mixture during heating and cooling, using water as the reaction mixture. We then considered the consecutive chemical reaction of the synthesis of cyclopentanediol from cyclopentadiene by studying the yield of this reaction. The results show that heating the reaction mixture increases significantly the yield of this synthesis reaction.

A two-point regulator control of a chemical reactor; Cooling system with a large inertia - PD algorithm

1983 ◽  
Vol 48 (9) ◽  
pp. 2627-2635 ◽  
Author(s):  
Josef Horák ◽  
František Jiráček ◽  
Libuše Ježová
Keyword(s):  
Temperature Control ◽  
Cooling System ◽  
Batch Reactor ◽  
Chemical Reactor ◽  
Slow Response ◽  
Practical Utilization ◽  
Laboratory Scale Reactor ◽  
Combined Simulation ◽  
Rate Of Response

The effect has been investigated of the gain of the derivative element of a PD controller on the quality of the temperature control of an exothermal reaction mixture in a batch reactor. The investigation concerned a reactor equipped with a cooling system whose rate of response could be varied in the range of several orders of magnitude. The results have lead to the conclusion that a slow response of the coolong system is difficult to make up for by using more sophisticated control algorithms. For the slow response of the cooling system the range of gain of the controller providing for a safe temperature control is narrow leaving essentially no margin for its practical utilization. The study combined simulation on a mathematical model with experimental verification of a laboratory scale reactor cooled by a submersible retractable cooler.

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