scholarly journals Forensic significance of skull development abnormalities

2003 ◽  
Vol 56 (11-12) ◽  
pp. 571-573
Author(s):  
Vladimir Pilija ◽  
Radenko Vukovic ◽  
Marija Mihalj ◽  
Slobodan Savovic ◽  
Mirela Eric
Keyword(s):  
Case Report ◽  
Bone Tissue ◽  
Basilar Artery ◽  
Bone Development ◽  
Genetic Disorders ◽  
Fatal Outcome ◽  
Brain Structures ◽  
Massive Hemorrhage ◽  
Skull Development ◽  
The Right

Introduction In the course of bone tissue development some genetic disorders such as exostoses and enostoses, may occur. Exostoses and enostoses represent bone tissue hyperplasia that can develop at any part of skeleton. Neurotrauma can cause fatal biological consequences, which is directly associated with skull development abnormalities. Case report This is a case report of a male cadaver 36 years of age. The autopsy revealed massive hemorrhage on the left side of the neck and the right side of the lower jaw. A major fissure of the arterial wall was found on the basilar artery. A bony, wart-like excrescence was found on the clivus of the occipital bone. Discussion Coinciding ruptures and consequential bleeding from basilar artery with presence of development abnormalities in the clivus region, suggest that one has to clearly distinguish the result of the injury from anomalies already existing in the skull. The position of the attacker can be determined by concise and objective investigation. Conclusion This is a case report of an anomaly in bone development: a bony, wart-like excrescence on the right side of the clivus. Due to neurotrauma and consequential sliding of brain structures, the damage of basilar artery and of the bony excrescence occurred, which led to bleeding and fatal outcome.

scholarly journals Management challenge of basilar artery occlusion in SUS: Case report

2021 ◽  
Author(s):  
Isadora Santos Ferreira ◽  
Mauricio Elias Nunes da Silva ◽  
Liz Barros Rebouças ◽  
Rafael Bernhart Carra ◽  
Rene de Araújo Gleizer ◽  
...  
Keyword(s):  
Case Report ◽  
Basilar Artery ◽  
Intravenous Thrombolysis ◽  
Tertiary Hospital ◽  
Artery Occlusion ◽  
Neurological Deficits ◽  
Basilar Artery Occlusion ◽  
High Morbidity ◽  
Basilar Artery Thrombosis ◽  
The Right

Context: Stroke caused by basilar artery occlusion is rare, corresponding to 1% of strokes. There is no consensus in the literature on the ideal management of this disease at acute phase. However, mechanical thrombectomy may be a viable treatment option. Case report: 68-year-old female, with no comorbidities, admitted to a secondary hospital 14h after headache, dizziness, vomiting and difficulty walking. She was disoriented, with severe dysarthria and dysphonia, horizontal and vertical ophthalmoparesis and pronation of the right upper limb (NIHSS: 4). Cranial tomography was normal and cranial angiotomography showed a basilar artery thrombosis. Patient was out of the window for intravenous thrombolysis and our hospital did not have another possibility of treatment. Due to high morbidity and mortality, also the possibility of neurological deterioration, medical contact was made with a tertiary hospital with hemodynamic service. During patient transference, she evolved with decreased level of consciousness, aphasia and tetraparesis (NIHSS: 18). Upon arrival at the hospital, a thrombectomy was performed due to an important clinical-radiological mismatch, 19 hours within symptoms onset and 3 hours after neurological worsening. After discharge, patient walked with assistance and physical examination showed a significant improvement in neurological deficits (NIHSS: 6). Conclusions: This case demonstrates the importance of engaging Brazil’s public health system in the management of acute ischemic stroke, especially in challenging cases such as basilar artery occlusion. This patient was the first admitted to our hospital to perform a thrombectomy after effective transference for a tertiary hospital and staff engagement of both hospitals.

scholarly journals Bilateral giant angiomyolipomas revealed after massive retroperitoneal hemorrhage: A case report

2014 ◽  
Vol 71 (4) ◽  
pp. 408-412 ◽  
Author(s):  
Sladjana Petrovic ◽  
Aleksandar Tasic ◽  
Dragan Mihailovic ◽  
Nikola Zivkovic ◽  
Marija Vitanovic ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Blood Vessels ◽  
Left Kidney ◽  
Vena Cava ◽  
Massive Hemorrhage ◽  
Epithelioid Angiomyolipoma ◽  
Retroperitoneal Hemorrhage ◽  
True Nature ◽  
The Right

Introduction. Angiomyolipomas (AML) are benign neoplasms composed of fat, smooth muscle and thick-walled blood vessels in varying proportions. These tumors have a significant female predominance. Case report. We reported a 61-year-old man with spontaneous rupture of AML. Computerized tomography revealed a change in morphology of both kidneys. Multiple lesions of fat density with dilated blood vessels were found in the left kidney. The right retroperitoneum was obliterated with a giant heterogeneous mass originating from the right kidney with a massive hemorrhage, active extravasations, compression of inferior the vena cava and intraperitoneal collections. After radical nephrectomy, histological examination revealed that the tumor was composed of relative proportions of fat, smooth muscle and blood vessels. We incidentally found small renal adenoma. Conclusion. The true nature of AML is unclear, but they are usually classified as hamartomas. Angiomyolipomas are generally benign lesions, although the epithelioid angiomyolipoma, a subtype that occurs in about 3% of cases, can behavior aggressively.

scholarly journals Cholestatic hepatitis associated with nimesulide: A case report

2009 ◽  
Vol 137 (9-10) ◽  
pp. 550-553 ◽  
Author(s):  
Snezana Lukic ◽  
Miodrag Krstic ◽  
Nemanja Damjanov ◽  
Ivan Boricic ◽  
Dragan Popovic ◽  
...  
Keyword(s):  
Case Report ◽  
Liver Biopsy ◽  
Liver Failure ◽  
Acute Hepatitis ◽  
Clinical Laboratory ◽  
Fatal Outcome ◽  
European Medicines Agency ◽  
Clinical Centre ◽  
Inflammatory Drugs ◽  
The Right

Introduction A toxic effect of drugs, including non-steroidal anti-inflammatory drugs, may be one of aetiological factors for the occurrence of acute hepatitis. Nimesulide is a selective cyclooxygenase-2 inhibitor, whose adverse effects on the liver range from acute hepatitis to more serious conditions, involving the development of acute liver failure and fatal outcome. Case Outline A female patient, aged 73, was admitted to the Gastroenterology and Hepatology Clinic of the Clinical Centre of Serbia in Belgrade because of liver failure. Due to the pain in the right knee, she received a therapy of 100 mg nimesulide in tablets, two times a day, for two months before admission to the Clinic. The analysis of the results of clinical, laboratory and radiographic examinations, and of histopathological findings of the liver biopsy showed that acute hepatitis was associated with the administration of nimesulide. Once the patient discontinued the intake of this drug, she fully convalesced. Conclusion The patient who received nimesulide over a period of two months developed acute hepatitis. In view of the similar cases described in literature and the fact that the use of nimesulide has been discontinued in a number of European countries and restricted by the European Medicines Agency, restriction or ban on the use of nimesulide on the Serbian market should be considered.

scholarly journals Isolated pathetick nerve paresis by compression from a dolichoectatic basilar artery: case report

2007 ◽  
Vol 65 (1) ◽  
pp. 176-178 ◽  
Author(s):  
Péricles Maranhão-Filho ◽  
Antonio Aversa Dutra do Souto ◽  
Jânio Nogueira
Keyword(s):  
Case Report ◽  
Magnetic Resonance ◽  
Basilar Artery ◽  
Head Position ◽  
Oblique Muscle ◽  
Ophthalmic Examination ◽  
Nerve Paresis ◽  
The Right ◽  
Superior Oblique Muscle ◽  
Superior Oblique

The article describes a woman with 53 year-old that has presented diplopia when looking down and adopted a tilted head position in order to read for the last six months. The neuro-ophthalmic examination shows isolated right superior oblique muscle paresis. The magnetic resonance and the angioresonance show the dolicoectatic basilar artery compressing the right ventral lateral brainstem.

scholarly journals Pulmonary mucormycosis presenting as central bronchopleural fistula—a case report with review of literature

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Elamparidhi Padmanaban ◽  
Preethi Kannan ◽  
Umamageswari Amirthalingam ◽  
Sudhakar Pitchumani ◽  
Padma Rekha
Keyword(s):  
Case Report ◽  
High Mortality ◽  
Bronchopleural Fistula ◽  
Fatal Outcome ◽  
Lower Lobe ◽  
High Index ◽  
Central Type ◽  
Pulmonary Mucormycosis ◽  
The Right ◽  
High Index Of Suspicion

Abstract Background Bronchopleural fistula (BFF) is a fistulous communication between the trachea or bronchus and the pleural space. Central type of bronchopleural fistula is usually post-surgical. Infective cause for central bronchopleural fistula is rare. This case report encompasses an infective cause of central bronchopleural fistula, mucormycosis. Pulmonary mucormycosis is a rapidly progressive condition with high mortality. A high index of suspicion and timely intervention is required to alleviate fatal outcome. The present case is discussed in detail about the clinical presentation and diagnostic imaging of pulmonary mucormycosis presenting with central bronchopleural fistula. Case presentation Thirty-five years old diabetic male, presented with fever, productive cough, mild haemoptysis and chest pain for 10 days duration. The patient was pale on general examination and had decreased breath sound in the right suprascapular and interscapular areas with coarse crackles in the right infrascapular and infra-axillary areas. The laboratory investigations were unremarkable except for anaemia and raised blood glucose level. Sputum examination on potassium hydroxide (KOH) mount showed broad aseptate hyphae. There was a loculated right hydropneumothorax with collapsed lung in chest radiograph. Multi-detector computed tomography of the thorax revealed central type of bronchopleural fistula with the right main bronchus, consolidation of the middle lobe and superior segment of the right lower lobe with multiple internal thick-walled cavities. Right pneumonectomy was performed as the patient did not improve on medical management and showed worsening of symptoms. Histopathological examination was suggestive of mucormycosis. Conclusion Central bronchopleural fistula due to an infective aetiology is uncommon. However, mucormycosis should be considered as a differential diagnosis in cases of central bronchopleural fistula with the destroyed lung, especially in diabetic individuals. Hence, a high index of suspicion is necessary for early diagnosis and management as mucormycosis is a rapidly progressive disease with delay in treatment leading to high mortality.

scholarly journals Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child

2021 ◽  
Author(s):  
Johanna Menger ◽  
Sofia Apostolidou ◽  
Carolin Edler ◽  
Inga Kniep ◽  
Robin Kobbe ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Tissue ◽  
Fatal Outcome ◽  
Pulmonary Hemorrhage ◽  
Massive Hemorrhage ◽  
University Hospital ◽  
Postmortem Computed Tomography ◽  
New Variant ◽  
Inhomogeneous Density ◽  
Va Ecmo

AbstractThis case report highlights details of a case of critical acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) with B1.1.7 variant in a 4-year-old girl who died due to pneumonia and pulmonary hemorrhage. The girl was referred to our University ECMO Center from another University hospital for veno-arterial extracorporeal membrane oxygenation (VA-ECMO). In the clinical course, superinfection with Pseudomonas aeruginosa was detected. Virological evidence of herpes simplex sepsis was also obtained in blood samples on her day of death. Transcription polymerase chain reaction (PCR) confirmed SARS-CoV-2 infection in lung tissue. Postmortem computed tomography showed pulmonary hemorrhage with inhomogeneous density values in both lungs. Lung tissue showed no ventilated areas. Autopsy revealed a massively congested lung with evidence of acute respiratory distress syndrome (ARDS) and pneumonia with multiple abscesses. Histopathology showed a mixture of diffuse alveolar injury with hyaline membranes, massive hemorrhage, and bronchopneumonia with multiple granulocytic abscesses. Cardiac examination revealed pericarditis. Suspicion of myocarditis or myocardial infarction could not be confirmed microscopically. To our knowledge, this is the first autopsy-based case report of the death of a previously healthy child due to the new variant B 1.1.7 in Germany.

scholarly journals Segmental myoclonus and basilar artery giant aneurysm case report

1992 ◽  
Vol 50 (4) ◽  
pp. 528-530
Author(s):  
J. Pitágoras de Mattos ◽  
Ana L. Zuma de Rosso ◽  
Eduardo Zayen ◽  
Sérgio A. P. Novis
Keyword(s):  
Ischemic Stroke ◽  
Essential Hypertension ◽  
Case Report ◽  
Angina Pectoris ◽  
Ct Scan ◽  
Basilar Artery ◽  
Giant Aneurysm ◽  
Neurologic Examination ◽  
Babinski Sign ◽  
The Right

A 70 years-old man was admitted at our hospital because of unstable angina pectoris. He had essential hypertension and right hemiplegia from a ischemic stroke two years before admission. On neurologic examination, it was found mental disorientation, unstable emotionality, right spastic hemiparesis with right Babinski sign, and segmental myoclonus affecting the superior lip and the palate (palatal nystagmus) on the right side. On the CT scan, a giant aneurysm of the basilar artery was detected. We conclude that the segmental myoclonus could be explained by ischemic lesions in the Guillain - Mollaret triangle.

scholarly journals Spontaneous rupture of giant liver hemangioma: Case report

2013 ◽  
Vol 141 (1-2) ◽  
pp. 95-99 ◽  
Author(s):  
Krstina Doklestic ◽  
Branislav Stefanovic ◽  
Aleksandar Karamarkovic ◽  
Vesna Bumbasirevic ◽  
Branislava Stefanovic ◽  
...  
Keyword(s):  
Case Report ◽  
Hemorrhagic Shock ◽  
Solid Tumor ◽  
Spontaneous Rupture ◽  
Fatal Outcome ◽  
Vascular Occlusion ◽  
Exploratory Laparotomy ◽  
Left Lobe ◽  
Liver Hemangioma ◽  
The Right

Introduction. Hemangioma is the most frequent benign solid tumor of the liver. It is well known that a giant liver hemangioma carries the risk of spontaneous rupture, followed by hemoperitoneum and hemorrhagic shock with possible fatal outcome. Case Outline. This is a case report of the spontaneous rupture of a giant cavernous hemangioma of the liver in an 85-year old patient. The patient was presented with abdominal pain and hemorrhagic shock. Emergency ultrasonography and computed tomography of the abdomen showed a heterogeneous ruptured solid tumor of the right liver lobe, multiple cysts in the left lobe and massive hemoperitoneum. The patient was successfully managed by immediate exploratory laparotomy, surgical enucleation of the hemangioma under intermittent inflow vascular occlusion, temporary perihepatic packing and planned second look relaparotomy. Conclusion. Immediate surgical procedure is indicated mandatory in unstable patients with a ruptured giant hemangioma of the liver. Surgical enucleation under intermittent inflow vascular occlusion and temporary perihepatic packing could be a life-saving procedure in those patients.

scholarly journals Aggressive intraabdominal fibromatosis

2006 ◽  
Vol 63 (9) ◽  
pp. 839-842 ◽  
Author(s):  
Radoje Colovic ◽  
Nikica Grubor ◽  
Vladimir Radak ◽  
Marijan Micev ◽  
Mirjana Stojkovic ◽  
...  
Keyword(s):  
Case Report ◽  
Tumor Recurrence ◽  
Common Iliac Artery ◽  
Fatal Outcome ◽  
Surgical Excision ◽  
Ascending Colon ◽  
Arterial Reconstruction ◽  
Mesenteric Fibromatosis ◽  
The Right ◽  
Graft Interposition

Background. Intraabdominal or mesenteric fibromatosis is a rare benign nonmetastatic neoplasm that appears as a sporadic lesion or in patients with familiar polyposis. Its evolution is unpredictable. About 10% of the cases show a very aggressive growth. Case report. We presented a 22-year-old woman in whom an aggressive intraabdominal fibromatosis had appeared during the first pregnancy as a well circumscribed ovoid tumor, involving the terminal ileum, the caecum, the ascending colon, the right kidney, the ureter, and the right common iliac artery. The tumor was excised with right colectomy, nephroureterectomy and resection of the involved artery using arterial reconstruction with graft interposition. Two years after the surgery the patient developed an inoperable tumor recurrence with a fatal outcome. Conclusion. In spite of a successful surgical excision during the original surgery intraabdominal or mesenteric fibromatosis might have an aggressive evolution leading to an inoperable tumor recurrency and a fatal outcome.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

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