scholarly journals Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child

2021 ◽  
Author(s):  
Johanna Menger ◽  
Sofia Apostolidou ◽  
Carolin Edler ◽  
Inga Kniep ◽  
Robin Kobbe ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Tissue ◽  
Fatal Outcome ◽  
Pulmonary Hemorrhage ◽  
Massive Hemorrhage ◽  
University Hospital ◽  
Postmortem Computed Tomography ◽  
New Variant ◽  
Inhomogeneous Density ◽  
Va Ecmo

AbstractThis case report highlights details of a case of critical acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) with B1.1.7 variant in a 4-year-old girl who died due to pneumonia and pulmonary hemorrhage. The girl was referred to our University ECMO Center from another University hospital for veno-arterial extracorporeal membrane oxygenation (VA-ECMO). In the clinical course, superinfection with Pseudomonas aeruginosa was detected. Virological evidence of herpes simplex sepsis was also obtained in blood samples on her day of death. Transcription polymerase chain reaction (PCR) confirmed SARS-CoV-2 infection in lung tissue. Postmortem computed tomography showed pulmonary hemorrhage with inhomogeneous density values in both lungs. Lung tissue showed no ventilated areas. Autopsy revealed a massively congested lung with evidence of acute respiratory distress syndrome (ARDS) and pneumonia with multiple abscesses. Histopathology showed a mixture of diffuse alveolar injury with hyaline membranes, massive hemorrhage, and bronchopneumonia with multiple granulocytic abscesses. Cardiac examination revealed pericarditis. Suspicion of myocarditis or myocardial infarction could not be confirmed microscopically. To our knowledge, this is the first autopsy-based case report of the death of a previously healthy child due to the new variant B 1.1.7 in Germany.

scholarly journals Forensic significance of skull development abnormalities

2003 ◽  
Vol 56 (11-12) ◽  
pp. 571-573
Author(s):  
Vladimir Pilija ◽  
Radenko Vukovic ◽  
Marija Mihalj ◽  
Slobodan Savovic ◽  
Mirela Eric
Keyword(s):  
Case Report ◽  
Bone Tissue ◽  
Basilar Artery ◽  
Bone Development ◽  
Genetic Disorders ◽  
Fatal Outcome ◽  
Brain Structures ◽  
Massive Hemorrhage ◽  
Skull Development ◽  
The Right

Introduction In the course of bone tissue development some genetic disorders such as exostoses and enostoses, may occur. Exostoses and enostoses represent bone tissue hyperplasia that can develop at any part of skeleton. Neurotrauma can cause fatal biological consequences, which is directly associated with skull development abnormalities. Case report This is a case report of a male cadaver 36 years of age. The autopsy revealed massive hemorrhage on the left side of the neck and the right side of the lower jaw. A major fissure of the arterial wall was found on the basilar artery. A bony, wart-like excrescence was found on the clivus of the occipital bone. Discussion Coinciding ruptures and consequential bleeding from basilar artery with presence of development abnormalities in the clivus region, suggest that one has to clearly distinguish the result of the injury from anomalies already existing in the skull. The position of the attacker can be determined by concise and objective investigation. Conclusion This is a case report of an anomaly in bone development: a bony, wart-like excrescence on the right side of the clivus. Due to neurotrauma and consequential sliding of brain structures, the damage of basilar artery and of the bony excrescence occurred, which led to bleeding and fatal outcome.

scholarly journals Dengue Fever with pulmonary alveolar hemorrhage - Common infection with uncommon association - rare case report

2019 ◽  
Vol 30 (1) ◽  
pp. 38-40
Author(s):  
B Saroj Kumar Prusty ◽  
Majed Abdul Basit Momin
Keyword(s):  
Case Report ◽  
Dengue Fever ◽  
Health Hazard ◽  
Fatal Outcome ◽  
Pulmonary Hemorrhage ◽  
Young Male ◽  
Rare Presentation ◽  
Serological Examination ◽  
Bronchial Wash ◽  
High Index Of Suspicion

Dengue fever (DF) is major health hazard around the world in recent decades especially in India. Flu like illness to polyserositis among common presentation of DF. Dengue fever presenting as pulmonary hemorrhage is rare. Here we present a case of 16 -year young male patient presented with fever and shortness of breath, initially diagnosed as dengue fever by serological examination. CT chest findings mimiking as pneumonia ,however further fall in hemoglobin and progressive dysnoea, bronchoscopy and bronchial wash cytology done which reveal association of pulmonary hemorrhage. This case report alerted clinicians about rare presentation and high index of suspicion of pulmonary hemorrhage in DF with dysnoea for early diagnosis and to avoid its fatal outcome. Bangladesh J Medicine Jan 2019; 30(1) : 38-40

Fatal outcome in dichorionic twin pregnancy with velamentous cord insertion – case report

2019 ◽  
Vol 4 (67) ◽  
pp. 194
Author(s):  
Aida Petca ◽  
Oana Calo ◽  
Florica Şandru ◽  
Răzvan Petca ◽  
Nicoleta Măru ◽  
...  
Keyword(s):  
Case Report ◽  
Twin Pregnancy ◽  
Fatal Outcome ◽  
Velamentous Cord Insertion

scholarly journals Successful extracorporeal membrane oxygenation resuscitation of patient with cardiogenic shock induced by phaeochromocytoma crisis mimicking hyperthyroidism: A case report

2021 ◽  
Vol 16 (1) ◽  
pp. 746-751
Author(s):  
Tao Wang ◽  
Qiancheng Xu ◽  
Xiaogan Jiang
Keyword(s):  
Case Report ◽  
Extracorporeal Membrane Oxygenation ◽  
Cardiogenic Shock ◽  
Tumour Size ◽  
Acute Onset ◽  
Left Ventricular ◽  
Vanillylmandelic Acid ◽  
Membrane Oxygenation ◽  
First Case ◽  
Va Ecmo

Abstract A 29-year-old woman presented to the emergency department with the acute onset of palpitations, shortness of breath, and haemoptysis. She reported having an abortion (56 days of pregnancy) 1 week before admission because of hyperthyroidism diagnosis during pregnancy. The first diagnoses considered were cardiomyopathy associated with hyperthyroidism, acute left ventricular failure, and hyperthyroidism crisis. The young woman’s cardiocirculatory system collapsed within several hours. Hence, venoarterial extracorporeal membrane oxygenation (VA ECMO) was performed for this patient. Over the next 3 days after ECMO was established, repeat transthoracic echocardiography showed gradual improvements in biventricular function, and later the patient recovered almost completely. The patient’s blood pressure increased to 230/130 mm Hg when the ECMO catheter was removed, and then the diagnosis of phaeochromocytoma was suspected. Computed tomography showed a left suprarenal tumour. The tumour size was 5.8 cm × 5.7 cm with central necrosis. The vanillylmandelic acid concentration was 63.15 mg/24 h. Post-operation, pathology confirmed phaeochromocytoma. To our knowledge, this is the first case report of a patient with cardiogenic shock induced by phaeochromocytoma crisis mimicking hyperthyroidism which was successfully resuscitated by VA ECMO.

scholarly journals Canine pyometra associated with Bacillus species: a case report

2018 ◽  
Vol 63 (No. 3) ◽  
pp. 143-149 ◽  
Author(s):  
MK Kim ◽  
HY Yoon ◽  
MH Lee ◽  
JH Kim
Keyword(s):  
Mammary Gland ◽  
Case Report ◽  
Bacillus Megaterium ◽  
Fatal Outcome ◽  
Bacillus Species ◽  
Bacterial Isolation ◽  
Sonographic Examination ◽  
First Time ◽  
Gland Tumour ◽  
Unilateral Mastectomy

An 11-year-old, female Maltese was presented for evaluation of a mammary gland tumour. An abdominal sonographic examination showed an echogenic, fluid-filled, dilated uterus; pyometra was also diagnosed. Ovariohysterectomy and unilateral mastectomy was performed and the dog recovered uneventfully. However, 11 h later, the dog’s condition suddenly deteriorated and it died on the day after the surgery. Bacillus circulans and Bacillus megaterium were isolated from its uterine content; these species had not been reported previously in canine pyometra. The two species were resistant to various antibiotics, including cefazolin used during the treatment. We describe for the first time the presentation, diagnosis, bacterial isolation and fatal outcome of B. circulans and B. megaterium infection in a Maltese dog with pyometra.

Overdose of Dologesic with a Fatal Outcome: A Case Report

2001 ◽  
Vol 8 (4) ◽  
pp. 207-211 ◽  
Author(s):  
CY Man
Keyword(s):  
Emergency Department ◽  
Cardiac Arrest ◽  
Case Report ◽  
Drug Overdose ◽  
Fatal Outcome ◽  
Common Cause ◽  
Accident And Emergency ◽  
Accident And Emergency Department

Dologesic is a commonly prescribed analgesic in accident and emergency department. Yet report of overdose with this drug is not common. We report a case in which the patient developed cardiac arrest within an hour of ingestion. Dextropropoxyphene, a component of the drug Dologesic, used to be a common cause of fatalities after drug overdose in the seventies. It is highly toxic in overdose and therefore caution should be exercised when prescribing this drug.

Exercise-Induced Pulmonary Hemorrhage in a Nonathlete: Case Report and Review of Physiology

Lung ◽  
2014 ◽  
Vol 192 (2) ◽  
pp. 329-331 ◽  
Author(s):  
Amit Diwakar ◽  
Gregory A. Schmidt
Keyword(s):  
Case Report ◽  
Pulmonary Hemorrhage ◽  
Exercise Induced

scholarly journals Severe Austrian Syndrome in an Immunocompromised Adult Patient – A Case Report

2018 ◽  
Vol 4 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Ioana Raluca Chirteș ◽  
Dragos Florea ◽  
Carmen Chiriac ◽  
Oana Maria Mărginean ◽  
Cristina Mănășturean ◽  
...  
Keyword(s):  
Case Report ◽  
Streptococcus Pneumoniae ◽  
Histopathological Examination ◽  
Fatal Outcome ◽  
Multiple Organ ◽  
Etiologic Agent ◽  
Acute Meningitis ◽  
History Of ◽  
Valvular Lesions ◽  
Formalin Fixed

AbstractBackground: Known also as Osler’s triad, Austrian syndrome is a complex pathology which consists of pneumonia, meningitis and endocarditis, all caused by the haematogenous dissemination of Streptococcus pneumoniae. The multivalvular lesions are responsible for a severe and potential lethal outcome.Case report: The case of a 51-year-old female patient, with a past medical history of splenectomy, is presented. She developed bronchopneumonia, acute meningitis and infective endocarditis as a result of Streptococcus pneumoniae infection and subsequently developed multiple organ dysfunction syndromes which led to a fatal outcome. Bacteriological tests did not reveal the etiological agent. The histopathological examination showed a severe multivalvular endocarditis, while a PCR based molecular analysis from formalin fixed valvular tissue identified Streptococcus pneumoniae as the etiologic agent.Conclusions: The presented case shows a rare syndrome with a high risk of morbidity and mortality. Following the broad-spectrum treatment and intensive therapeutic support, the patient made unfavourable progress which raised differential diagnosis problems. In this case, the post-mortem diagnosis demonstrated multiple valvular lesions occurred as a result of endocarditis.

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