scholarly journals Lupus vulgaris: Isolation of Mycobacterium tuberculosis from the affected skin scraping and mucous membranes

2006 ◽  
Vol 59 (11-12) ◽  
pp. 580-583
Author(s):  
Marina Jovanovic ◽  
Ruza Sente ◽  
Zoran Golusin ◽  
Tatjana Kurucin ◽  
Ljuba Vujanovic ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Mucous Membrane ◽  
Standard Of Living ◽  
Lupus Vulgaris ◽  
Skin Scraping ◽  
Drug Combination Therapy ◽  
Mucous Membranes ◽  
Skin Tuberculosis ◽  
Diagnostic Criterion

Introduction. In the second half of the last century skin tuberculosis has become a rarity. With the appearance of resistance to different kinds of pathogenes, HIV-immunodeficiency and decreasing standard of living, the incidence of skin tuberculosis increses. Lupus vulgaris is a chronic form of the secondary tuberculosis of the skin. Case report. This is a case report of a 66-year-old woman who presented with a growing, painless, brownish-red, slab-shaped, jelly, cutanesous mass, 2.5 centimeters in diameter, on the tip of her nose, reaching the mucous membrane of the nose. Results. Apart from accelerated erythrocyte sedimentation rate (43/73) and a positive tuberculosis test (Mantoux 10 TU=25x25 mm), all relevant findings were within reference values. Using Ziehl-Neelsen staining, no acido-resistent bacilli were found. The skin scraping sample, taken from the affected skin and the mucous membrane, was cultivated in Lowenstein medium base, and this resulted with cultivation of Mycobacterium tuberculosis. Using three-drug combination therapy for ten months, complete remission was achieved. Conclusion. Successful cultivation of pathogens represents an absolute diagnostic criterion. We present a case of a woman with lupus vulgaris, because there is a small number of cases documented around the world where the diagnosis was confirmed by culture of Mycobacterium tuberculosis. .

scholarly journals Topical Occlusive Corticosteroid Therapy for the Treatment of Gingival Manifestation of Mucous Membrane Pemphigoid - a Case Report

Folia Medica ◽  
2020 ◽  
Vol 62 (4) ◽  
pp. 866-870
Author(s):  
Liliya Kavlakova ◽  
Svitlana Bachurska
Keyword(s):  
Case Report ◽  
Oral Health ◽  
Oral Cavity ◽  
Topical Corticosteroid ◽  
Mucous Membrane ◽  
Vital Role ◽  
Mucous Membrane Pemphigoid ◽  
Mucous Membranes ◽  
Symptomatic Effect ◽  
Common Manifestation

Mucous membrane pemphigoid (MMP) is a chronic, autoimmune, subepithelial vesiculobullous disease that very frequently affects the mucous membranes and less often the skin. Oral cavity is the most commonly affected site and desquamative gingivitis (DG) is the most common manifestation. This is the main reason why dentists play a vital role in the diagnosis and managing the oral health of patients. Treatment is usually challenging, however, it only can achieve temporary symptomatic effect. We report a case of desquamative gingivi-tis, manifestation of MMP that was treated successfully with topical corticosteroid. The latter was applied by using of individual made custom trays to improve clinical efficacy. 

scholarly journals Atypical Clinical and Serological Manifestation of Pemphigus Vegetans: A Case Report and Review of the Literature

2017 ◽  
Vol 9 (1) ◽  
pp. 121-130 ◽  
Author(s):  
Rebecca Mergler ◽  
Andreas Kerstan ◽  
Enno Schmidt ◽  
Matthias Goebeler ◽  
Sandrine Benoit
Keyword(s):  
Case Report ◽  
Mucous Membrane ◽  
Delayed Diagnosis ◽  
Pemphigus Vulgaris ◽  
Review Of The Literature ◽  
Unusual Manifestation ◽  
Anglophone Literature ◽  
Mucous Membranes ◽  
The Right ◽  
Pemphigus Vegetans

Pemphigus vegetans (PVeg) is a rare variant of pemphigus vulgaris characterized by pustules and/or papillomatous vegetations, preferentially affecting intertriginous and periorificial areas. Exceptional manifestations may be misdiagnosed resulting in delayed diagnosis and treatment. Diagnosis is confirmed by immunofluorescence and detection of anti-desmoglein (Dsg) 3 and/or anti-Dsg1 antibodies. We herein report an unusual manifestation of PVeg. At the time of first presentation, lesions were restricted to the right ring finger’s tip. Although mucous membranes were initially not affected, high levels of anti-Dsg3 antibodies were detected while anti-Dsg1 and anti-desmocollin (Dsc) 1, 2, and 3 antibodies were absent. To compare our immunological findings with previous reports, all accessible Anglophone literature published since December 1988 was evaluated. We identified 52 patients suffering from PVeg, 7 of these showed anti-Dsg3 antibodies without any mucous membrane involvement. Notably, the detection of anti-Dsg1 and anti-Dsg3 antibodies does not necessarily correlate with the involvement of skin and/or mucous membranes. This might be due to more specific and complex antibody constellations in nonclassical or atypical pemphigus.

scholarly journals Disseminated Cutaneous Tuberculosis like Fungal Sporotrichosis Successfully Treated With Terbinafine: A Rare Case Report

2021 ◽  
Vol 1 (1) ◽  
pp. 69-72
Author(s):  
Anil Gautam ◽  
Bijay Subedi ◽  
Janak Awasthi ◽  
Suman Adhikari
Keyword(s):  
Case Report ◽  
Cutaneous Leishmaniasis ◽  
Adult Male ◽  
Rare Case ◽  
Lupus Vulgaris ◽  
Diagnostic Dilemma ◽  
Cutaneous Tuberculosis ◽  
Rare Case Report ◽  
Old Adult ◽  
Skin Tuberculosis

Occurrence of Sporotrichosis is uncommon in Nepal. Here, we describe a case of cutaneous Sporotrichosis of 43 years old adult male working as a farmer from Pokhara-30, Nepal with unusual skin tuberculosis like presentation since 3 years, initiating from the unusual location in right pinna. Histopathological observation was suggestive of cutaneous tuberculosis, lupus vulgaris, cutaneous leishmaniasis due to overlapping findings during biopsy. The case was diagnosed by the pharma­cological intervention observing the effect of drugs i.e., terbinafine. The purpose of reporting this serendipitous case is to enhance timely diagnosis, avoid the diagnostic dilemma for future references.

Verrucous Psoriasis Successfully Treated with Ixekizumab: A Case Report with Review Literature

2020 ◽  
Vol 103 (9) ◽  
pp. 948-951
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Rare Variant ◽  
Psoriasis Vulgaris ◽  
Review Literature ◽  
Antituberculous Therapy ◽  
Plaque Type ◽  
History Of

Verrucous psoriasis is a rare variant of plaque-type psoriasis with only about 35 cases reported. The authors reported a man with a history of psoriasis vulgaris for seven years, presented with progressive verrucous hyperkeratotic plaques on both legs for three years. His earlier investigations favored the diagnosis of tuberculosis verrucosa cutis. After completing the antituberculous therapy, the lesions persisted. The later investigations favored a rare subtype of psoriasis named verrucous psoriasis. Keywords: Verrucous psoriasis, Tuberculosis verrucosa cutis, Mycobacterium tuberculosis, Ixekixumab

scholarly journals HIV Patient with Mucous Membrane Pemphigoid: A Case Report

2014 ◽  
Vol 24 (2) ◽  
pp. 179 ◽  
Author(s):  
AP Singh ◽  
TR Chaitra ◽  
TL Ravishankar ◽  
SP Singh ◽  
AK Mohapatra
Keyword(s):  
Case Report ◽  
Mucous Membrane ◽  
Mucous Membrane Pemphigoid

PATHOHISTOLOGICAL CHANGES IN PIGS WITH MYCOPLASMOSIS

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
N. B. Kolych ◽  
◽  
N. V. Hudz ◽  
Keyword(s):  
Mucous Membrane ◽  
Alveolar Wall ◽  
Soft Or ◽  
Diffuse Infiltration ◽  
Small Areas ◽  
Perivascular Edema ◽  
Mucous Membranes ◽  
The Right ◽  
The Brain ◽  
Dark Pink

A pathological autopsy was performed on 6 corpses of piglets in the first week of life who died from mycoplasmosis. Examination of the visible mucous membranes revealed hyperemia of the mucous membrane of the nasal cavity and thymus. Simultaneous lesions of the pharyngeal, parotid, cervical, mandibular lymph nodes were noted. They were slightly enlarged, from dark pink to dark red. The heart is irregularly shaped due to the expansion of the right ventricle or the diffuse expansion of all departments. Lungs have doughy consistency, uneven color. In some cases, there are diffuse red areas covering the entire lobe of the lungs, in other cases, there is a defeat of small areas. The liver has a smooth surface, soft or pasty consistency, the parenchyma pattern is slightly smoothed in section. The color of the liver is different: dark red areas, without clear boundaries turn into creamy-clay. Flatulence was a characteristic feature of the stomach and intestines. Catarrhal enteritis was registered in animals, which manifested itself in the form of moderate hyperemia of the intestinal mucosa and serous membranes. Microscopically, there is a significant blood supply to the vessels in the lungs. Alveoli are half fall down, in the form of slit-like lumens. In areas of tissue infiltration by inflammatory infiltrate, the alveolar wall is thickened, alveocytes are in a state of turbid swelling and vacuolar dystrophy, they are impregnated with erythrocytes. Peribronchial pneumonia of lymphocytic character is observed. The liver is in a state of acute venous hyperemia. The central and intraparticle capillaries are sharply dilated and filled with blood in some lobes, and the hepatic beams are compressed accordingly. In the center of other lobes, diffuse infiltration of liver tissue by erythrocytes as a consequence of diapedesis is noted. Hepatocytes are in a state of granular dystrophy. Destructive changes are strongly expressed in the mucous membrane of the small intestine: desquamation of the epithelium, necrosis of epitheliocytes and villi, destruction of crypts. In the brain tissue, there is dilation of the lumens of large and small blood vessels, extracellular and perivascular edema, areas of reactive necrosis.

scholarly journals Prostatic tuberculosis: case report

2008 ◽  
Vol 126 (4) ◽  
pp. 227-228 ◽  
Author(s):  
Daniel Sáenz-Abad ◽  
Santiago Letona-Carbajo ◽  
José Luis de Benito-Arévalo ◽  
Isabel Sanioaquín-Conde ◽  
Francisco José Ruiz-Ruiz
Keyword(s):  
Computed Tomography ◽  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Urine Culture ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Tuberculosis Case ◽  
Immunocompetent Patients

CONTEXT: Tuberculosis of the prostate has mainly been described in immunocompromised patients. However, it can exceptionally be found as an isolated lesion in immunocompetent patients. CASE REPORT: We report a case of prostatic tuberculosis in a young, healthy and immunocompetent patient with unremarkable findings from intravenous urographic examination. Computed tomography showed an abscess in the prostate and Mycobacterium tuberculosis was isolated in a urine culture. Treatment with isoniazid, rifampin and pyrazinamide was successful.

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