scholarly journals Serum calcium and phosphorus concentration and alkaline phosphatase activity in healthy children during growth and development

2008 ◽  
Vol 61 (7-8) ◽  
pp. 393-399 ◽  
Author(s):  
Ljiljana Savic ◽  
Dejan Savic
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Serum Calcium ◽  
Alkaline Phosphatase Activity ◽  
Growth And Development ◽  
Age Groups ◽  
Growth Spurt ◽  
Phosphorus Concentration ◽  
Healthy Children ◽  
Calcium And Phosphorus

Introduction. Many changes happen during growth and development in an organism as a result of important hormone changes, especially biohumoral ones. These changes make a problem when interpreting biochemical results in pediatric population. The most important changes are intensive calcium and phosphorus metabolic turnover in bone tissue with changes in alkaline phosphatase activity as a result of osteoblast activity. The aim of this study was to follow the serum calcium and phosphorus concentration and alkaline phosphatase activity in children 1-15 years old in different growth and development period and of different sexes and to fortify the influence of growth and development dynamics on biohumoral status in healthy male and female children. Material and methods. We evaluated 117 healthy children of both sexes from 1-15 years of age and divided them into three age groups: 1-5, 6-10 and 11-15 years. We followed the serum calcium and phosphorus concentration and alkaline phosphatase activity in different groups and in different sexes. Results and conclusion. Our investigation found significantly higher values of serum calcium in boys than in girls with no important changes between the age groups and significantly higher values of serum phosphorus in the youngest age group in all children and in different sexes with no important sex differences. Alkaline phosphatase activity followed the growth spurt and was the biggest in 6-10 years group in girls and in 11-15 years group in boys.

scholarly journals Effects of Cowpea-Amaranth Intercropping and Fertiliser Application on Soil Phosphatase Activities, Available Soil Phosphorus, and Crop Growth Response

Agronomy ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 79 ◽  
Author(s):  
Buhlebelive Mndzebele ◽  
Bhekumthetho Ncube ◽  
Melake Fessehazion ◽  
Tafadzwanashe Mabhaudhi ◽  
Stephen Amoo ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Crop Production ◽  
Soil Phosphorus ◽  
Phosphorus Concentration ◽  
Acid And Alkaline Phosphatase ◽  
Available Soil Phosphorus ◽  
Fertiliser Application ◽  
Inorganic Fertilisers

Low available soil phosphorus (P) is associated with its immobility, which renders it unavailable for plant uptake. In addition, farmers normally apply inorganic fertilisers to legumes to activate soil-bound phosphorus using root exudates. Sufficient soil mineral nutrition is key to sustainable crop production, and hence food and nutritional security. The aim of this study was to quantify the acid and alkaline phosphatase activity as an indicator of P supply and availability under varying levels of nitrogen, phosphorus and potassium (NPK) fertilization and different cropping systems. An intercropping (cowpea and amaranth) and fertiliser (control, 25%, 50%, and 100% of the recommended NPK levels) field trial was laid out in a 2 × 4 factorial treatment structure in a completely randomized design (CRD) with four replications. There was higher acid and alkaline phosphatase activity in the rhizosphere of cowpea and amaranth grown as sole crops compared to those from intercropping. The cowpea and amaranth plants grown without fertiliser or 25% NPK had the highest rhizospheric phosphatase activity, while 100% NPK application exhibited the least. The markedly higher phosphatase activity from the low fertiliser application treatments indicates the possible stimulation of microbial activity to supplement P demands for the crops. The study revealed that the application of lower rates inorganic fertilisers in a legume intercrop stimulates the activity of the phosphatase enzymes, which can subsequently liberate soil-bound phosphorus. Plant tissue phosphorus concentration of cowpea and amaranth plants increased proportionately to the increase in fertiliser application up to 50% of the recommended NPK level. The land equivalent ratio (LER) was greater than 1, indicating that it is more beneficial to intercrop cowpea and amaranth as opposed to growing them as sole crops. Overall, the application of NPK fertilizer to amounts of up to 50%, based on the results of this study, appear to be better than 100% in terms of biomass accumulation and phosphate activity.

scholarly journals Indicators of bone metabolism in patients of psychiatric clinic on the background of dimephosphone intake

2016 ◽  
Vol 97 (5) ◽  
pp. 669-673
Author(s):  
R Yu Il’ina ◽  
O O Pasynkova ◽  
L R Mukhamedzhanova ◽  
L E Ziganshina
Keyword(s):  
Alkaline Phosphatase ◽  
Acid Phosphatase ◽  
Mental Disorders ◽  
Bone Metabolism ◽  
Phosphatase Activity ◽  
Serum Calcium ◽  
Alkaline Phosphatase Activity ◽  
Psychiatric Patients ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase

Aim. To study the indicators of bone metabolism in patients of psychiatric clinics on the background of dimephosphone oral intake.Methods. Research was conducted at the Republican Clinical Psychiatric Hospital named after V.M. Bekhterev (Kazan). 64 patients (36 men and 28 women) aged 45 to 68 years (mean age 56.8±6.9 years) with various forms of mental disorders taking psychotropic drugs for the period of 3 years and over were examined. Resorption markers were determined - D-pyridinoline in urine, serum tartrate-resistant acid phosphatase, alkaline phosphatase, and the content of total and ionized serum calcium. All patients were divided into two groups: those who received dimephosphone in the combined systemic therapy and those who did not. The average duration of the dimephosphone administration was 22±4.2 days, the patients undergone on average 2.6±1.44 courses of treatment during 6 months.Results. The activity of tartrate-resistant acid phosphatase in psychiatric patients was higher compared with those of the control group. The maximum value was registered in patients who were not taking dimephosphone. The alkaline phosphatase activity was the highest in mentally healthy patients of the control group. In psychiatric patients treated with dimephosphone, alkaline phosphatase activity was 20% lower compared with the control group. The minimum values of alkaline phosphatase were registered in patients with mental disorders not taking dimephosphone. When studying the concentration of total and ionized serum calcium there were no significant differences between patients of comparison group and psychiatric patients.Conclusion. Shift in processes of bone remodeling toward its resorption indicates a high risk of pathological fractures in psychiatric patients and the need for osteoporosis prevention; identified changes in biochemical markers of osteoporosis on the background of dimephosphone intake allow to recommend it for the treatment of diagnosed osteoporosis in a psychiatric hospital settings.

Hypercalciuric Hypophosphatemic Rickets, Mineral Balance, Bone Histomorphometry, and Therapeutic Implications of Hypercalciuria

PEDIATRICS ◽  
1989 ◽  
Vol 84 (2) ◽  
pp. 276-280
Author(s):  
C. Chen ◽  
T. Carpenter ◽  
N. Steg ◽  
R. Baron ◽  
C. Anast
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Hypophosphatemic Rickets ◽  
Balance Study ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D ◽  
Study Results ◽  
Calcium And Phosphorus

A 14-year-old Turkish boy had severe rickets that had been clinically evident since he was 2 years of age. When he was 5 years of age, he had normal serum calcium and phosphorus levels and increased alkaline phosphatase activity. Treatment with modest dosages of vitamin D (5000 U/d for 3 weeks) resulted in hypercalcemia. At 10 years of age, high-dose vitamin D (40 000 U/d) plus phosphorus (1.1 g/d) therapy for 20 days resulted in symptomatic nephrolithiasis. When, 14 years of age, he had normocalcemia, hypophosphatemia, increased alkaline phosphatase activity, and normal circulating parathyroid hormone concentration. Levels of 25-hydroxyvitamin D were normal but those of 1,25-dihydroxyvitamin D were markedly increased. Rickets and osteopenia were evident on radiographs, and osteomalacia was present on trabecular bone obtained at biopsy. Balance study results showed increased intestinal absorption of calcium and phosphorus, hypercalciuria, and increased urinary phosphorus excretion. This patient manifests an unusual form of hypophosphatemic rickets in which hypercalciuria is a cardinal feature. In contrast with most varieties of hypophosphatemia, this disorder is characterized by appropriately increased production of 1,25-dihydroxyvitamin D in response to hypophosphatemia. It is recommended that urinary calcium excretion be assessed in all patients with hypophosphatemic rickets so that appropriate therapy will be instituted.

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