scholarly journals Gluten-related disorders

2021 ◽  
pp. 100-100
Author(s):  
Biljana Vuletic ◽  
Aleksandar Kocovic ◽  
Marija Mladenovic ◽  
Zoran Lekovic ◽  
Vladimir Radlovic ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Clinical Features ◽  
Dermatitis Herpetiformis ◽  
Current Knowledge ◽  
Diagnosis And Treatment ◽  
Gluten Sensitivity ◽  
Wheat Allergy ◽  
Clinical Expression ◽  
Barley Flour ◽  
Gluten Ataxia

Gluten-related disorders are a heterogeneous group of clinical entities caused by intolerance of wheat, rye, and barley flour components. They occur in 3-5% of genetically predisposed persons and based on pathogenic and clinical features are classified into celiac disease, non-celiac gluten sensitivity, and wheat allergy. There are also specific entities such as dermatitis herpetiformis or gluten ataxia, which can occur either within the celiac disease or independently. This article based on the current knowledge shows the basic details of the pathogenesis, clinical expression, diagnosis, and treatment of these disorders.

scholarly journals The many faces of the problem of intolerance to gluten.

2018 ◽  
Vol 96 (2) ◽  
pp. 123-128
Author(s):  
M. A. Livsan ◽  
M. F. Osipenko ◽  
Natalya V. Zayakina ◽  
T. S. Krolevets
Keyword(s):  
Celiac Disease ◽  
Dermatitis Herpetiformis ◽  
Current Data ◽  
Gluten Sensitivity ◽  
Wheat Allergy ◽  
Serological Markers ◽  
Gluten Intolerance ◽  
Rising Incidence ◽  
The Many

Rising incidence of different variants of gluten intolerance associated with changes in eating behaviorin many countries, changes in the technology of growing and processing crops, new culinary technologies. Until recently, celiac disease, dermatitis herpetiformis and wheat allergy were the only known disease with a proven role of gluten in their pathogenesis. Non-celiac gluten sensitivity (NCGS) - a new syndrome of intolerance to gluten. This pathology can be suspected in patients with persistent intestinal and extra-intestinal symptoms clearly associated with the intake of foods containing gluten, the absence of serological markers of celiac disease or suspected allergy to wheat. The paper presents the current data on the epidemiology, etiology and pathogenesis, clinical features and diagnosis NCGS.

scholarly journals Prevalence of gluten-related disorders in Asia-Pacific region: a systematic review

2019 ◽  
Vol 28 (1) ◽  
pp. 95-105
Author(s):  
Sara Ashtari ◽  
Mohamad Amin Pourhoseingholi ◽  
Kamran Rostami ◽  
Mohammad Rostami-Nejad ◽  
Luca Busani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Celiac Disease ◽  
Dermatitis Herpetiformis ◽  
Asia Pacific ◽  
High Risk Population ◽  
Healthy Children ◽  
Pacific Region ◽  
Wheat Allergy ◽  
Asia Pacific Region ◽  
Gluten Ataxia

Background & Aims: The epidemiology of gluten-related disorders (GRDs) is still an open field to be explored. We conducted this systematic review based on the current epidemiology knowledge of GRDs, focusing on the changing prevalence of GRDs reported in the Asia-Pacific region.Methods: We searched Medline, PubMed, Scopus, Web of Science and Cochrane database with the following MeSH terms and keywords: celiac disease (CD), wheat allergy (WA), non-celiac gluten sensitivity (NCGS), dermatitis herpetiformis (DH) and gluten ataxia (GA) and the prevalence studies published from January 1991 to January 2018. Each article was cross-referenced with “Asia-Pacific region” and countries in this regionsuch as Australia, New Zealand, India, Pakistan, Turkey, Iran and others.Results: We included 66 studies, which reported the prevalence of GRDs in the Asia-Pacific region. Prevalence of celiac disease was 0.32%-1.41% in healthy children and 0.05%-1.22% in the adult population, while the prevalence in the high risk population was higher (0.6%-11.8%). Previous studies have shown a very low incidence of dermatitis herpetiformis (DH) (<0.001%) and gluten ataxia (GA) in this area. Few studies on NCGS outbreaks have been found in this area due to the lack of specific diagnostic biomarkers. Wheat allergy (WA), although uncommon in most Asian-Pacific countries, is the most common cause of anaphylaxis in this region.Conclusion: The results of this systematic review suggest the need to plan further proper epidemiological studies in order to understand the natural history of GRDs and to assess its burden on health systems.

scholarly journals Neurological disorders associated with gluten sensitivity

2017 ◽  
Vol 89 (2) ◽  
pp. 99-102
Author(s):  
D A Degterev ◽  
I V Damulin ◽  
A I Parfenov
Keyword(s):  
Clinical Features ◽  
Neurological Disorders ◽  
Gluten Free Diet ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Gluten Ataxia

The review considers the pathogenetic, clinical, and therapeutic aspects of neurological disorders associated with gluten sensitivity. Gluten ataxia and polyneuropathy are most common. The clinical features of neurological disorders in patients with gluten sensitivity and the effects of a gluten-free diet are described.

scholarly journals Celiac disease, wheat allergy and non celiac gluten sensitivity

2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Iman Nasr ◽  
Latifa Al Shekeili ◽  
Humaid A Al Wahshi ◽  
Mohammad H Nasr ◽  
Paul J Ciclitira
Keyword(s):  
Celiac Disease ◽  
Gluten Sensitivity ◽  
Wheat Allergy

Gluten ataxia is better classified as non-celiac gluten sensitivity than as celiac disease: a comparative clinical study

2015 ◽  
Vol 64 (2) ◽  
pp. 558-564 ◽  
Author(s):  
Luis Rodrigo ◽  
Carlos Hernández-Lahoz ◽  
Eugenia Lauret ◽  
Maria Rodriguez-Peláez ◽  
Miroslav Soucek ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Clinical Study ◽  
Gluten Sensitivity ◽  
Gluten Ataxia ◽  
Comparative Clinical Study

scholarly journals The impact of gluten ingestion on pathogenesis of neurological disorders

2019 ◽  
Vol 73 ◽  
pp. 197-216
Author(s):  
Piotr Grzegrzółka ◽  
Robert Jarzyna
Keyword(s):  
Autism Spectrum Disorder ◽  
Nervous System ◽  
Celiac Disease ◽  
Human Body ◽  
Neurological Disorders ◽  
Gastrointestinal Symptoms ◽  
Autism Spectrum ◽  
Gluten Sensitivity ◽  
Wheat Allergy ◽  
The Impact

For many years the spectrum of gluten-related disorders had been limited only to celiac disease and its typical gastrointestinal symptoms. In the last few years, not only new disorders like non-celiac gluten sensitivity have been described, but also pathogeneses of celiac disease and wheat allergy have been better understood. It is also known that impaired gluten tolerance in many cases leads to appearance of extraintestinal symptoms that may affect any organ or system of the human body including the nervous system that may be the cause of some neurological disorders such as ataxia, neuropathy, autism spectrum disorder (ASD) or schizophrenia. In this paper we present the spectrum of neurological disorders, whose pathogeneses may depend on gluten ingestion and some proposed mechanisms elucidating those pathogeneses.

scholarly journals Recent Advances in Dermatitis Herpetiformis

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Kimiko Nakajima
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Immune Responses ◽  
Dermatitis Herpetiformis ◽  
Gluten Sensitivity ◽  
Bullous Disease ◽  
Autoimmune Bullous Disease ◽  
Multifactorial Disorders ◽  
Epidermal Transglutaminase ◽  
Transglutaminase 3

Dermatitis herpetiformis is an autoimmune bullous disease that is associated with gluten sensitivity which typically presents as celiac disease. As both conditions are multifactorial disorders, it is not clear how specific pathogenetic mechanisms may lead to the dysregulation of immune responses in the skin and small bowel, respectively. Recent studies have demonstrated that IgA and antibodies against epidermal transglutaminase 3 play an important role in the pathogenesis of dermatitis herpetiformis. Here, we review recent immunopathological progress in understanding the pathogenesis of dermatitis herpetiformis.

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