scholarly journals Blood transfusion in horses

2010 ◽  
Vol 64 (1-2) ◽  
pp. 137-142
Author(s):  
Dragisa Trailovic ◽  
Sasa Laus ◽  
Stefan Djokovic
Keyword(s):  
Blood Transfusion ◽  
Blood Loss ◽  
Blood Coagulation ◽  
Fluid Therapy ◽  
Whole Blood ◽  
Coagulation Factor ◽  
Blood Groups ◽  
Blood Bank ◽  
Fresh Blood ◽  
Efficient Manner

Fluid therapy includes blood transfusion which presents the most efficient manner of treating hypovolaemia caused by blood loss, even though whole blood can be used as a therapeutic means in other cases as well - in deficits of the blood coagulation factor, exhaustion of the antiprotease system, hypoproteinaemia, primarily hypoalbuminaemia, and others. The application of fresh blood has an advantage over preserved blood, which does not lessen the importance of setting up a blood bank, in particular in cases when the blood groups of the donors are precisely determined. .

THE EFFECT OF EARLY BLOOD TRANSFUSION ON THE OUTCOME OF GASTROINTESTINAL HAEMORRHAGE

1987 ◽  
Author(s):  
S D Blair ◽  
S B Javanvrin ◽  
C N McCollum ◽  
R M Greenhalgh
Keyword(s):  
Blood Transfusion ◽  
Blood Coagulation ◽  
Whole Blood ◽  
Randomised Trial ◽  
Gastrointestinal Haemorrhage ◽  
Clotting Time ◽  
Prospective Randomised Trial ◽  
Coagulation Tests ◽  
To Receive ◽  
Upper Gastrointestinal

It has been suggested that mortality due to upper gastrointestinal haemorrhage may be reduced by restricting blood transfusion [1], We have assessed whether this is due to an anticoagulant effect in a prospective randomised trial.One hundred patients with severe, acute gastrointestinal haemorrhage were randomised to receive either at least 2 units of blood during the first 24 hours of admission, or no blood unless their haemaglobin was lessthan 8g/dl or they were shocked. Minor bleeds and varices were excluded As hypercoagulation cannot be measured using conventional coagulation tests, fresh whole blood coagulation was measured by the Biobridge Impedance Clotting Time (ICT). Coagulation was assessed at 24 hour intervals and compared to age matched controls with the results expressed as mean ± sem.The ICT on admission for the transfusion group (n=50) was 3.2±0.2 mins compared to 10±0.2 mins in controls. This hyper-coagulable state was partially reversed to 6.4±0.3 mins at 24 hours (p<0.001). The 50 allocated to receive no blood had a similar ICT on admission of 4.4±0.4 mins but the hypercoagulable state was maintained with ICT at 24 hours of 4.320.4 mins. Only 2 patients not transfused rebled compared to 15 in the early transfusion group (p<0.001). Five patients died, and they were all in the early transfusion group.These findings show there is a hypercoagulable response to haemorrhage which is partially reversed by blood transfusion leading to rebleeding

scholarly journals A Comparative Study of Storage Related Haematological Changes in Whole Blood and PRBC in Blood Bank of a Tertiary Care Hospital

2020 ◽  
Vol 9 (2) ◽  
pp. 1-7
Author(s):  
Pratibha Shirvastava ◽  
Shyamoli Dutta
Keyword(s):  
Blood Transfusion ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Whole Blood ◽  
Tertiary Care ◽  
Blood Bank ◽  
Clotting Factor ◽  
Research Centre ◽  
Care Hospital ◽  
Haematological Changes

Background: Blood transfusion is very common in present era. Now day’s whole blood transfusion is common but also the blood product like red blood cell, white blood cell, platelets, clotting factor, plasma can be done .the aim of study to know the storage related changes in whole blood, packed red blood cell. Subjects and Methods: In our institution we have selected 100 voluntary blood donors sample in blood bank of Teerthankar Mahaveer medical college and research centre, Moradabad up to 12 month. Results: The store blood is Followed up to 35th days .during regular interval 1st, 7th, 14th, 21st, 28th and 35th day, in the blood there is significant change in and all other component in all sample. Conclusion: In the case of storage of blood in blood bank. As the number day of store is more the haematological changes is more significant.

Blood products and fluid therapy

2021 ◽  
pp. 449-470
Author(s):  
Nicholas Eaddy ◽  
Alexandra Cardinal
Keyword(s):  
Blood Transfusion ◽  
Fluid Therapy ◽  
Coagulation Factor ◽  
Patient Blood Management ◽  
Blood Products ◽  
Blood Management ◽  
Massive Blood Transfusion ◽  
Essential Components ◽  
The Common ◽  
Specific Management

This chapter describes the blood products which are commonly required as part of anaesthetic practice, including red cells, plasma, cryoprecipitate, platelet concentrate, and concentrated coagulation factor preparations. The essential components of patient blood management, aiming to reduce the requirement for transfusion, are described. The principles and practice of massive blood transfusion are described. The specific management of Jehovah’s Witnesses, and other patients who decline blood transfusion, is discussed. The chapter finishes with a discussion of the common intravenous fluid preparations which are used in practice, and how to use them appropriately.

Massive Blood Transfusion

1980 ◽  
Vol 8 (2) ◽  
pp. 152-157 ◽  
Author(s):  
Ronald E. Benson ◽  
James P. Isbister
Keyword(s):  
Blood Transfusion ◽  
Adverse Effects ◽  
Blood Loss ◽  
Oxygen Transport ◽  
Clinical Setting ◽  
Fresh Blood ◽  
Massive Blood Transfusion ◽  
Massive Blood Loss ◽  
Wide Range ◽  
Underlying Pathophysiology

Massive blood transfusion is associated with a wide range of adverse effects, some of which are understood, but controversy surrounds the effects of massive blood loss and transfusion on haemostasis and oxygen transport. Until we have a better understanding of the underlying pathophysiology and while storage of blood remains imperfect, there is a good case for the empirical use of super-fresh blood in this clinical setting. A practical approach to the exsanguinated patient is presented.

Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin versus autologous fresh whole blood transfusion

1992 ◽  
Vol 6 (3) ◽  
pp. 319-323 ◽  
Author(s):  
Catherine Vedrinne ◽  
Claude Girard ◽  
Olivier Jegaden ◽  
Pascale Blanc ◽  
Hélene Bouvier ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Whole Blood ◽  
High Dose ◽  
High Dose Aprotinin

scholarly journals The modern concept of intensive therapy of coagulopathy, which is complicate polytrauma and shock

2019 ◽  
Vol 2 (8) ◽  
pp. 4-15
Author(s):  
V.I. Cherniy
Keyword(s):  
Blood Loss ◽  
Blood Coagulation ◽  
Intensive Therapy ◽  
Fatal Outcome ◽  
Coagulation Factor ◽  
Individual Characteristics ◽  
Factor Vii ◽  
Modern Concept ◽  
Fourth Edition ◽  
Coagulation Factor Vii

The statute presents the fourth edition (The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition, 2016) of European recommendations on the treatment of severe blood loss and coagulopathy caused by injury. More than 50% of all trauma patients with a fatal outcome die within 24 hours after injury. After hospitalization in a third of patients with trauma, the bleeding is coagulopathic. They significantly increase the risk of multiple organ failure and death compared with patients with similar trauma in the absence of coagulopathy. Early acute coagulopathy associated with traumatic injury is multifactorial: 1) hemorrhage induced shock; 2) tissue damage with the release of tissue thromboplastin and the development of thrombinemia; 3) activation of anticoagulant and fibrinolytic systems. The severity of coagulation disorders is determined by the influence of environmental factors, metabolic disorders (acidosis, hypothermia, tissue hypoperfusion and consumption coagulopathy) and therapeutic strategy. Coagulopathies can be associated with trauma to the brain, liver, and patient's individual characteristics, which include age, heredity, comorbidities, and medication, especially oral anticoagulants. Coagulation monitoring (internationally normalized ratio (INR) and APTT), characterizes only the beginning of the 2nd phase of blood coagulation, and represents the generation of only the first 4% of thrombin. Therefore, the performance of a normal coagulogram may be normal, although the general condition of the blood coagulation system is pathological. Late diagnosis of traumatic coagulopathy may affect the outcome. A new concept of reanimation of patients with massive bleeding has been presented, the immediate introduction of coagulation components (RBC, native plasma and platelets in a 1: 1: 1 ratio), tranexamic acid, fresh frozen plasma, fibrinogen concentrate, desmopressin, prothrombin complex concentrate, recombinant activated coagulation factor VII (rFVIIa). Currently, the issue of using fresh whole blood for resuscitation in case of injury and massive blood loss is relevant.

scholarly journals Blood Bank Service: An Experience at Newly Established Birat Medical College and Teaching Hospital, Tankisinuwari, Morang, Nepal

2017 ◽  
Vol 2 (1) ◽  
pp. 98-101
Author(s):  
Santosh Upadhyaya Kafle ◽  
K K Jha ◽  
M Sigh ◽  
R Rana
Keyword(s):  
Blood Group ◽  
Teaching Hospital ◽  
Whole Blood ◽  
Blood Groups ◽  
Blood Bank ◽  
Blood Collection ◽  
Age Group ◽  
Total Blood ◽  
Medical College ◽  
Gynecology And Obstetrics

IntroductionBlood bank service facility of blood collection, storage and dispatching began from 19 June 2016 in the new blood bank and transfusion service unit, at Birat Medical College & Teaching Hospital, Tankisinuwari, Morang, Nepal, with the support of Nepal Red Cross Society. As the supply of blood is finite, the inappropriate use of blood transfusion units and its component in the world exist, hence there is a need to monitor and regulate these services.ObjectivesThe objective of this study is to know and identify different blood groups and its utilization pattern to meet the demand for future preparedness and to identify the total blood unit, which are being, replaced back.MethodologyThis retrospective study was conducted at BMCTH, Tankisinuwari, Morang for component dispatches from 19th June, 2016 to 19th February, 2017. Requisitions for whole blood requirement for patients from various departments were reviewed regarding the department request, the whole blood requested and whether being replaced, blood group and socio-demographic profile.ResultsOut of 193 transfusion units dispatched, 28 patients were male and 165 patients were females respectively B positive blood groups were most common, followed by A positive, O positive, AB positive, both AB and O negate respectively. The largest numbers of requisitions were from Gynecology and Obstetrics ward in the hospital, while 22 requisites were from other health centers. Majority of the requisitions were for 51- 60 years age group from the local district Morang. The total number of blood units replaced were 38, out of which 5 for males and 33 for females respectively.ConclusionB positive was the predominant requested blood group, with Gynecology and Obstetrics ward demanding the most requests, among 51-60 years age group from Morang district. The total blood units being replaced were very less in number with some requisition forms, which lacked essential details.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 98-101

scholarly journals Whole blood transfusion in small animals: indications and effects

2011 ◽  
Vol 83 (2) ◽  
pp. 611-617 ◽  
Author(s):  
Luís F Godinho-Cunha ◽  
Rui M. R. F Ferreira ◽  
Ana C Silvestre-Ferreira
Keyword(s):  
Body Temperature ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Whole Blood ◽  
Survival Rates ◽  
Underlying Disease ◽  
Acute Blood Loss ◽  
Transfusion Therapy ◽  
Transfusion Volume ◽  
The Difference

Transfusion therapy is a major resource that can improve the patient's capability to overcome the underlying disease. However, the effects of whole blood infusion, and how they affect the patient's outcome, are not yet clear. For this study, a protocol was developed in order to monitor a group of 15 animals (9 dogs, 6 cats) that received a total of 19 transfusions; 3 animals received more than one transfusion each. The most common indications for blood transfusion included acute blood loss (47%), coagulopathy (33%) and other anaemias (20%). The mean pre-transfusion packed cell volume (PCV) of animals with acute blood loss (18%) was higher than in the group of coagulopathy (15%) or other anaemias (15%). The survival rates at 6 days after transfusion were greater in the coagulopathy (80.0%) and other anaemias (66.7%) than in the group of acute blood loss (42.9%). After transfusion, pulse rate ( p <0.01) and platelet count ( p <0.05) decreased significantly, and there was a significant increase in body temperature of the animals that suffered from hypothermia before the transfusion ( p <0.05). Overall survival was predictable based upon posttransfusion body temperature, observed PCV change, the difference between the obtained and the calculated PCV, and administered transfusion volume ( p <0.05)

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