scholarly journals Influence of dental filling material type on the concentration of interleukin 9 in the samples of gingival crevicular fluid

2016 ◽  
Vol 73 (8) ◽  
pp. 728-734 ◽  
Author(s):  
Vladimir Stefanovic ◽  
Ervin Taso ◽  
Aleksandra Petkovic-Curcin ◽  
Mirjana Djukic ◽  
Milka Gardasevic ◽  
...  
Keyword(s):  
Dental Pulp ◽  
Wound Repair ◽  
Gingival Crevicular Fluid ◽  
Prospective Clinical Study ◽  
Filling Material ◽  
Gingival Index ◽  
Dental Fillings ◽  
Dental Filling ◽  
Filling Materials ◽  
Pulp Inflammation

Background/Aim. Several cytokines and lymphokines (IL1?, ENA78, IL6, TNF?, IL8 and S100A8) are expressed during dental pulp inflammation. Analysis of gingival crevicu-lar fluid (GCF) offers a non-invasive means of studying gen-eral host response in oral cavity. Although GCF levels of various mediators could reflect the state of inflammation both in dental pulp and gingiva adjacent to a tooth, GCF samples of those without significant gingivitis could be inter-preted as reflection of pulpal process. The aim of this study was to investigate IL9 GCF values in patients with dental car-ies and to assess possible influence of various dental fillings materials on local IL9 production. Methods. The study group included 90 patients, aged 18?70, with inclusion and exclusion criteria in the prospective clinical study. Of the 6 types of material used for the restoration of prepared cavities, 3 were intended for temporary and 3 for definitive restora-tion. According to dental fillings weight, all the participants were divided into 3 groups: those with fillings lighter than 0.50 g, those with 0.50?1.00 g, and those with fillings heavier than 1.00 g. Samples were taken from gingival sulcus using the filter paper technique. Clinical parameters were deter-mined by bleeding index, plaque index (Silness-Lou, 0?3), gingival index (0?3), and gingival sulcus depth. Cytokine con-centrations were assessed using commercially available cy-tomix. Results. According to the weight of dental fillings, there was a clear decreament trend of IL9 values meaning that dental defects greater than 1.00 g of dental filling were associated with lower GCF IL9 concentration. The IL9 val-ues correlated with the degree of gingival index and depth of gingival sulcus, being higher with more advanced gingivitis and more pronounced anatomical changes in the tooth edge. Different filling materials exerted various local IL9 responses. Zink polycarbonate cement and amalgam fillings induced a significant and long-lasting local IL9 decrement, while the use of Tetric EvoCeram and GMA-BISK significantly increased IL9 levels. Conclusion. The obtained results indicate that IL9 GCF could be regarded as a measure of odontoblasts? re-sponse to the extensity of dental caries. The type of material used for dental fillings could profoundly alter biological func-tion of gingival and pulpal cells. Also, the results obtained in this study suggest that some materials could even enhance wound repair by modulating macrophage activation.

scholarly journals Exposure to Dental Filling Materials and the Risk of Dementia: A Population-Based Nested Case Control Study in Taiwan

2019 ◽  
Vol 16 (18) ◽  
pp. 3283 ◽  
Author(s):  
Natalia Mikhailichenko ◽  
Kimitoshi Yagami ◽  
Jeng-Yuan Chiou ◽  
Jing-Yang Huang ◽  
Yu-Hsun Wang ◽  
...  
Keyword(s):  
Large Scale ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Toxic Substances ◽  
Filling Material ◽  
Dental Practice ◽  
Dental Filling ◽  
Filling Materials ◽  
People With Dementia ◽  
Somatic Diseases

When studying the range of toxic substances triggering dementia, special attention should be paid to the materials used in dental practice, particularly to dental fillings containing amalgam. This necessitated conducting large-scale epidemiologic studies. The aim of our research was to determine the risk factors for developing dementia when filling materials containing amalgam are used in dental practice. In order to achieve the set goals, the following tasks were undertaken: (1) The social and demographic characteristics of the examined patients were studied; (2) the spectrum of concomitant somatic diseases was determined in patients of different gender and age; and (3) the relationship between dementia incidence and the volume of dental filling material containing amalgam was identified in patients with different somatic diseases. In general, the research conducted did not reveal any direct relationship between the development of dementia and the volume of filling material containing amalgam. However, among the people with dementia, there were persons for whom its progression was accelerated in cases where a large volume of dental filling material containing amalgam was present.

scholarly journals Mechanical Stress Exploration Inside of Dental Filling Materials by Means of Electronic Speckle Pattern Interferometry / Shearography

2017 ◽  
Vol 54 (4) ◽  
pp. 616-619
Author(s):  
Alina Ormenisan ◽  
Daniel Tamas Szava ◽  
Ioan Szava ◽  
Ciprian Dalai
Keyword(s):  
Speckle Pattern ◽  
Glass Ionomer Cement ◽  
Academic Research ◽  
Mechanical Stresses ◽  
Electronic Speckle Pattern Interferometry ◽  
Filling Material ◽  
Dental Tissues ◽  
Vertical Loading ◽  
Dental Filling ◽  
Filling Materials

Possible causes of microleakage and microfractures of dental fillings are often in the center of many academic research and investigations. Some authors found that one important cause of microleakage is the contraction/ shrinkage of the filling materials during polymerization. The purpose of this study is to demonstrate that microcracks and consequent microleakage is influenced by mechanical stresses occurring inside of dental filling materials and at the interface of the dental cavities and dental filling materials. We also tried to evaluate the deformation of some dental filling material types during mechanical loading. Cylindrical specimens were made of different types of dental filling materials, namely microhybrid composites and glass ionomer cement. Some extracted teeth were prepared with class II cavities, and filled. The lateral swelling of the tested specimens and the deformation of the filled teeth during vertical axial loading was measured with an optical method, ESPI/ Shearography.Of the tested specimen, the least deformable dental filling materials were the composite materials. During occlusal vertical loading of the filled teeth, there were found that mechanical stresses were different inside of the filling material than inside of the walls of the dental tissues, mechanical stressed being concentrated at the restoration interface. The ESPI/Shearography meth ode proved to be very useful for investigation in this field. Due to mechanical stresses accumulating at the interface of the dental filling material and the walls of the dental cavity, it is possible that later microcracks to appear due to masticatory forces.

Tissue Reaction to Subcutaneous Implantation of SuperEBA (Reinforced Zinc Oxide Cement) Used as Root-End Filling Material: A Histological Study in Rats

2016 ◽  
Vol 695 ◽  
pp. 247-251
Author(s):  
Alexandru Andrei Iliescu ◽  
Cristian Marian Petcu ◽  
Ileana Cristiana Petcu ◽  
Irina Maria Gheorghiu ◽  
Andrei Iliescu ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Histological Study ◽  
Tissue Reaction ◽  
Tissue Response ◽  
Successful Outcome ◽  
Filling Material ◽  
Clinical Value ◽  
Filling Materials ◽  
Retrograde Filling ◽  
Specific Tissue

The retrograde filling is a critical step to a successful outcome of the endodontic surgery. Despite the progress in the technology of novel root-end filling materials, zinc oxide-eugenol cement superEBA is still preserving its clinical value on long-term basis. The study aimed to reconsider the tissue response to the initial irritating effect of this material. Silicon tubes filled with superEBA were subcutaneously implanted for 120 days in white Wistar rats which were afterwards sacrificed. The connective tissue surrounding the superEBA implants revealed fibroblast proliferation and a definite reparatory process without inflammatory reaction. A non-specific tissue healing in progress around the implants, without calcifications, necrosis, and apoptosis was also described after 4 months. SuperEBA proved on animal model that its cytotoxicity is reducing gradually in time until no adverse reaction is observed. The reduced content in eugenol compared to other surgical zinc oxide cements and the benefic effect of o-ethoxybenzoic acid are the support to reconsider SuperEBA as a biocompatible retrograde filling material.

scholarly journals The behaviour of composites, glass ionomers and compomers in erosive conditions – in vitro study

2014 ◽  
Vol 60 (5) ◽  
pp. 200-203
Author(s):  
Andreea Borş ◽  
Cristina Molnar-Varlam ◽  
Melinda Székely
Keyword(s):  
Surface Roughness ◽  
Wear Resistance ◽  
Erosive Wear ◽  
In Vitro Study ◽  
Vitro Study ◽  
Initial Surface ◽  
Dental Filling ◽  
Filling Materials ◽  
Restorative Materials

Abstract Objective: The aim of this in vitro study was to evaluate the influence of erosive conditions on the wear resistance of aesthetic direct restorative materials. Methods: Six dental filling materials were tested: two composites (Filtek Z550 and X-tra fil), two compomers (Dyract Extra and Twinky Star) and two glass ionomers (Ketac Molar and Fuji II LC). Twenty disks (10mm×2mm) of each material were prepared (n=120) and kept in artificial saliva at 37˚C for 24 hours. Specimens were cycled in acidic soft drink (Coca-Cola) 5×/day, for 5’, over 30 days. Initial surface roughness ISR (Ra-μm) and final surface roughness FSR were measured using a profilometer. The wear rate was calculated as difference of final minus the initial roughness (ΔSR=FSR-ISR). For statistical analysis t-test and one-way ANOVA test were used by GraphPad Prism version 5.03 statistical software. The level of significance was set at p<0.05. Results: The erosive wear rates (mean±SD, μm) after exposure to acidic beverage were: 0.30±0.03 (Ketac Molar), 0.28±0.04 (Fuji II LC), 0.27±0.00 (Filtek Z550), 0.23±0.01 (X-tra fil), 0.20±0.00 (Twinky Star) and 0.14±0.01 Dyract Extra, respectively. There were significant differences between the tested materials (p<0.05). Conclusions: Dental filling materials had different behaviour under the same erosive condition, however all investigated aesthetic restorative materials showed surface degradation. These findings suggest that erosive wear resistance of tooth coloured restoratives could influence their longevity in intraoral acidic conditions. Acknowledgements: The study was supported by the Internal Research Grant no. 5/30.01.2013 of the University of Medicine and Pharmacy of Tirgu Mureş.

scholarly journals Investigation of the Sedimentation Property of Backfill Material on the Basis of Rheological Test: A Case Study of Iron Tailings

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Yong Wang ◽  
Aixiang Wu ◽  
Lianfu Zhang ◽  
Hongjiang Wang ◽  
Fei Jin
Keyword(s):  
Shear Stress ◽  
Shear Rate ◽  
Mass Concentration ◽  
Filling Material ◽  
Quantitative Characterization ◽  
Filling Materials ◽  
Characterization Studies ◽  
Rheological Test ◽  
Sedimentation Property

Sedimentation of filling materials could cause pipe blocking accident in mines. However, few quantitative characterization studies have investigated the sedimentation characteristics of filling materials. In this study, the sedimentation property of iron tailings with a cement-sand ratio of 1 : 4 and mass concentration of 73%∼82% was investigated based on rheology measurements. Results showed that shear stress increased as shear rate rose from 0 s−1to 120 s−1. The shear stress increased as the filling material concentration increased as well. However, when the shear rate was reversed from 120 s−1to 0 s−1, the shear stress presented an increase-constant-decrease change pattern as the mass concentration increases in the rheological curve. Accordingly, the sedimentation performance of iron tailings filling material was divided into three types: intense sedimentation (the ascending rheological curve) in the mass concentration range of 73%∼76%, slight sedimentation (the constant rheological curve) in the mass concentration range of 77%∼79%, and almost no sedimentation (the descending rheological curve) in the mass concentration range of 80%∼82%. The associated mechanism involving slurry mass concentration-rheological curves-sedimentation performance was illustrated. A correlation between the pipeline rheology and filling material sedimentation performance was established, which provides a practical guide to avoid pipeline blocking while transporting the filling material.

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