scholarly journals Urticaria caused by Arcanobacterium haemolyticum: Diagnostic and therapeutic failures

Author(s):  
Ljiljana Suvajdzic ◽  
Ekaterina Mrdja ◽  
Mirjana Bogavac ◽  
Ljubomir Dzambas

We presented a case of seventeen-year-old girl exhibiting mild symptoms of sore throat, a marked urticarial rash and heavy desquamations of the skin on palms and soles. According to the antibiogram and diagnosis of Streptococcus non A non B group obtained in routine laboratory procedure, the patient was treated with penicillin; however, ineffectively. Escalation of urticaria and failure of the initial penicillin therapy shifted the diagnosis towards exanthema toxoalergicum and thus to treatment with corticosteroids and antihistamines, yet with no improvement. The culture was repeated with a new specimen. Diagnosis was made according to the specific pattern in a double CAMP test, and confirmed by the ApiCoryne diagnostic set (BioMerieux). With respect to cultural traits, the isolate mimicked Streptococcus pyogenes, yet developing specific pattern in a double CAMP test that directed our diagnosis towards coryneform microorganisms. The diagnosis of Arcanobacterium haemolyticum was confirmed with 99.9% probability rate and T = 0.75.

1992 ◽  
Vol 106 (11) ◽  
pp. 1000-1001 ◽  
Author(s):  
M. Barnham ◽  
R. A. Bradwell

AbstractA patient is reported with a peritonsillar abscess yielding Arcanobacterium haemolyticum. This appears to be only the fifth such case described in the medical literature and the first from Europe. The organism has been reported as an occasional cause of tonsillopharyngitis with rash, resembling infection with Streptococcus pyogenes but often unresponsive to penicillin therapy. A. haemolyticum easily passes unrecognized in bacteriological cultures as a result of its slow growth, coryneform appearance in the Gram's stain and weak haemolytic activity on conventional laboratory media.


2019 ◽  
Vol 2 (1) ◽  
pp. 9 ◽  
Author(s):  
Markus Peurla ◽  
Pekka Hänninen ◽  
Eeva-Liisa Eskelinen

Preparing pioloform/formvar support films on transmission electron microscopy (TEM) grids is a routine laboratory procedure in practically all electron microscopy units. In current practice, these grids are manually placed on the support film one by one using special tweezers, a process requiring a steady hand. The work is often ergonomically awkward to continue for a longer period of time. In this article, we describe a low-cost, computer vision-guided robot arm that automatically places the grids on the film. The success rate of the prototype robot is 90%, which is comparable to an experienced laboratory technician.


1971 ◽  
Vol 69 (3) ◽  
pp. 355-360 ◽  
Author(s):  
P. W. Ross

SUMMARYBacteriological monitoring of penicillin therapy in 30 children with streptococcal sore throats was performed by means of salivary and throat-swab culture, on the first, third, fifth and ninth days after therapy had started. Counts of beta-haemolytic streptococci per ml. of saliva were also performed.Results showed that salivary culture and estimation of the numbers of beta-haemolytic streptococci in the saliva were much more sensitive indices of the effectiveness of penicillin treatment than throat-swab culture.


1938 ◽  
Vol 38 (3) ◽  
pp. 384-391 ◽  
Author(s):  
E. Juel Henningsen ◽  
J. Ernst

A report is given of a milk epidemic of septic sore throat, comprising about 100 cases.The epidemic originated from a cow with a slight degree of mastitis, produced by a Streptococcus pyogenes (Lancefield's group A).The same Streptococcus (which we did not succeed in typing) was isolated from 74% of the patients examined and from three persons who were handling the milk.It seems reasonable to assume that the cow was infected from the milkers. Owing to particular conditions in the distribution of the raw milk, it is possible that the milk delivered raw in the village involved on one day a massive contamination.The epidemic is characterized as moderately severe. No case terminated fatally.


2017 ◽  
Vol 16 (3) ◽  
pp. 145-148
Author(s):  
Olivia Jones ◽  
◽  
Aram Salehi ◽  

The presentation of a ‘sore throat’ is common and often requires only symptomatic treatment. This is the case of a 20-year-old female who presented with persistent symptoms of a sore throat. On admission she had raised inflammatory markers and a subsequent blood culture demonstrated a fusobacterium necrophorum and arcanobacterium haemolyticum bacteraemia. Further investigations established an internal jugular vein thrombosis, confirming the diagnosis of Lemierre’s syndrome. This case highlights the importance of further investigation when a sore throat fails to improve, and to remember this often-forgotten syndrome.


1999 ◽  
Vol 30 (4) ◽  
pp. 332-334 ◽  
Author(s):  
Vera Fantinato ◽  
A. O. C. Jorge ◽  
Mário. T. Shimizu

Streptococcus salivarius strains, isolated from children with and without sore throat, were tested for bacteriocin production against Streptococcus pyogenes. S. salivarius strains producing bacteriocin-like inhibitory substances (BLIS) against S. pyogenes were more frequently found in children without sore throat. These results suggest that these children may be protected against sore throat by the presence of BLIS-positive S. salivarius strains.


2001 ◽  
Vol 127 (2) ◽  
pp. 179-184 ◽  
Author(s):  
U. KATZENELL ◽  
J. SHEMER ◽  
Y. BAR-DAYAN

The purpose of this article is to define the distinguishing characteristics of food-borne streptococcal pharyngitis by reviewing the literature. The main cause of this infection lies in poor handling and preservation of cold salads, usually those which contain eggs and are prepared some hours before serving. A shorter incubation period and a higher attack rate (51–90%) than in transmission by droplets was noted. The epidemics tend to occur in warm climates and in the hottest months of the year. Streptococcus pyogenes seems to originate from the pharynx or hand lesions of a food handler. In comparison to airborne transmission symptoms such as sore throat, pharyngeal erythema, and enlarged tonsils, submandibular lymphadenopathy are more frequent than coughing and coryza. Seven out of 17 reports revealed an M-untypeable serotype, which may possess virulent characteristics. Penicillin prophylaxis was shown to limit additional spread of the infection. There were no non-suppurative sequels, and suppurative sequels were very rare. We assume that the guidelines for the prevention of food poisoning would apply to food-borne streptococcal pharyngitis. Food handlers should be supervised to ensure they comply with strict rules of preparation and storage of food. Cold salads, especially those containing eggs, should not be left overnight before serving.


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