It has long been known a variety of forms of pathological processes arising as a consequence of malarial poisoning. Both in Russian and in foreign literature there are many works indicating damage to a wide variety of systems and organs caused by malaria. Here we have a disease of the respiratory tract (Grisoll, Sverzhevsky, Sokolowski, Striimpel, Three ant af ill idea, etc.), and heart disease (Striimpel), and lesions of the digestive system with colitis, dysentery forms (Werner, Kushev, Luria, Svenson and others), cholecystitis (Luria), appendicitis, etc. Many authors point to the defeat of renal tissue in malaria (A to vbyan c. Barbitsky, Laveran, Luria. Matthes, Puchek, Striimpel, etc. .), Belyaeva, Kushe, Svenson, Striimpel, Chistovich, etc. indicate an increase in the spleen and liver. Thebesky, and later Yeligulashvili, describe itchy skin as a manifestation of malaria. Further, diseases of the nervous system, mental illness, etc. are known. The pathological and histological studies of Vinogradov, Shirokogorov, and others also speak of the same diversity.