A Neglected Varietal Name for the Mexican Axolotl

Hobart M. Smith

doi:10.2307/1563280

The Ultrastructure of Myocardial Cells in Normal and Cardiac Lethal Mutant Mexican Axolotls, (Ambystoma Mexicanum)

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100067303 ◽

1970 ◽

Vol 28 ◽

pp. 62-63

Author(s):

Larry F. Lemanski ◽

Eldridge M. Bertke ◽

J. T. Justus

Keyword(s):

Fine Structure ◽

Heart Development ◽

Osmium Tetroxide ◽

Picric Acid ◽

Ambystoma Mexicanum ◽

Recessive Mutation ◽

Acid Mixture ◽

Myocardial Cells ◽

Lethal Mutant ◽

Mexican Axolotl

A recessive mutation has been recently described in the Mexican Axolotl, Ambystoma mexicanum; in which the heart forms structurally, but does not contract (Humphrey, 1968. Anat. Rec. 160:475). In this study, the fine structure of myocardial cells from normal (+/+; +/c) and cardiac lethal mutant (c/c) embryos at Harrison's stage 40 was compared. The hearts were fixed in a 0.1 M phosphate buffered formaldehyde-glutaraldehyde-picric acid-styphnic acid mixture and were post fixed in 0.1 M s-collidine buffered 1% osmium tetroxide. A detailed study of heart development in normal and mutant embryos from stages 25-46 will be described elsewhere.

Arrangement of Mitochondria in Spermatozoa of the Mexican Axolotl, Ambystoma Mexicanum

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010007357x ◽

1973 ◽

Vol 31 ◽

pp. 626-627

Author(s):

Ezzatollah Keyhani ◽

Larry F. Lemanski ◽

Sharon L. Lemanski

Keyword(s):

Plasma Membrane ◽

Sperm Motility ◽

Substrate Oxidation ◽

Ambystoma Mexicanum ◽

Axial Filament ◽

Mexican Axolotl ◽

Middle Piece

Energy for sperm motility is provided by both glycolytic and respiratory pathways. Mitochondria are involved in the latter pathway and conserve energy of substrate oxidation by coupling to phosphorylation. During spermatogenesis, the mitochondria undergo extensive transformation which in many species leads to the formation of a nebemkem. The nebemkem subsequently forms into a helix around the axial filament complex in the middle piece of spermatozoa.Immature spermatozoa of axolotls contain numerous small spherical mitochondria which are randomly distributed throughout the cytoplasm (Fig. 1). As maturation progresses, the mitochondria appear to migrate to the middle piece region where they become tightly packed to form a crystalline-like sheath. The cytoplasm in this region is no longer abundant (Fig. 2) and the plasma membrane is now closely apposed to the outside of the mitochondrial layer.

Experimental studies on a mutant gene (cl) in the Mexican axolotl which affects cell membrane formation in embryos from females

Developmental Biology ◽

10.1016/0012-1606(73)90227-3 ◽

1973 ◽

Vol 32 (1) ◽

pp. 155-166 ◽

Cited By ~ 8

Author(s):

Carole R. Carroll ◽

E.B. Van Deusen

Keyword(s):

Cell Membrane ◽

Experimental Studies ◽

Mutant Gene ◽

Mexican Axolotl ◽

Membrane Formation

Effect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl (Ambystoma)

BMC Genomics ◽

10.1186/1471-2164-9-78 ◽

2008 ◽

Vol 9 (1) ◽

pp. 78 ◽

Cited By ~ 25

Author(s):

Robert B Page ◽

Stephen R Voss ◽

Amy K Samuels ◽

Jeramiah J Smith ◽

Srikrishna Putta ◽

...

Keyword(s):

Thyroid Hormone ◽

Transcriptional Response ◽

Hormone Concentration ◽

Mexican Axolotl ◽

Thyroid Hormone Concentration

Further studies on the maternal effect of theo gene in the Mexican axolotl

Journal of Experimental Zoology ◽

10.1002/jez.1401810214 ◽

1972 ◽

Vol 181 (2) ◽

pp. 271-280 ◽

Cited By ~ 23

Author(s):

Robert Briggs

Keyword(s):

Maternal Effect ◽

Mexican Axolotl

Conformation studies of myofibril-inducing RNA using the Mexican axolotl

Developmental Biology ◽

10.1016/j.ydbio.2007.03.204 ◽

2007 ◽

Vol 306 (1) ◽

pp. 346-347

Author(s):

Elena Rueda-de-Leon ◽

Gagani Athauda ◽

Chi Zhang ◽

Jennifer A. Maier ◽

Pingping Jia ◽

...

Keyword(s):

Mexican Axolotl

Cloning and sequencing of the cDNA for an RNA-binding protein from the Mexican axolotl: binding affinity of the in vitro synthesized protein

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ◽

10.1016/s0167-4781(98)00071-2 ◽

1998 ◽

Vol 1398 (3) ◽

pp. 265-274 ◽

Cited By ~ 1

Author(s):

Rajula Bhatia ◽

Arun Gaur ◽

Larry F. Lemanski ◽

Dipak K. Dube

Keyword(s):

Binding Affinity ◽

Rna Binding ◽

Binding Protein ◽

Rna Binding Protein ◽

Cloning And Sequencing ◽

Mexican Axolotl

Recent decline and potential distribution in the last remnant area of the microendemic Mexican axolotl (Ambystoma mexicanum)

Biological Conservation ◽

10.1016/j.biocon.2009.07.008 ◽

2009 ◽

Vol 142 (12) ◽

pp. 2881-2885 ◽

Cited By ~ 44

Author(s):

Victoria Contreras ◽

Enrique Martínez-Meyer ◽

Elsa Valiente ◽

Luis Zambrano

Keyword(s):

Potential Distribution ◽

Ambystoma Mexicanum ◽

Mexican Axolotl

A semilethal factor (v) in the Mexican axolotl (Siredon mexicanum) and its maternal effect

Developmental Biology ◽

10.1016/0012-1606(62)90051-9 ◽

1962 ◽

Vol 4 (3) ◽

pp. 423-451 ◽

Cited By ~ 19

Author(s):

R.R. Humphrey

Keyword(s):

Maternal Effect ◽

Factor V ◽

Mexican Axolotl

Geography is more important than life history in the recent diversification of the tiger salamander complex

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.2014719118 ◽

2021 ◽

Vol 118 (17) ◽

pp. e2014719118

Author(s):

Kathryn M. Everson ◽

Levi N. Gray ◽

Angela G. Jones ◽

Nicolette M. Lawrence ◽

Mary E. Foley ◽

...

Keyword(s):

Life History ◽

Gene Flow ◽

Genetic Differentiation ◽

Population Genetic ◽

Tiger Salamander ◽

Life History Variation ◽

Mexican Axolotl ◽

Population Genetic Differentiation ◽

Wide Range ◽

Lineage Divergence

The North American tiger salamander species complex, including its best-known species, the Mexican axolotl, has long been a source of biological fascination. The complex exhibits a wide range of variation in developmental life history strategies, including populations and individuals that undergo metamorphosis; those able to forego metamorphosis and retain a larval, aquatic lifestyle (i.e., paedomorphosis); and those that do both. The evolution of a paedomorphic life history state is thought to lead to increased population genetic differentiation and ultimately reproductive isolation and speciation, but the degree to which it has shaped population- and species-level divergence is poorly understood. Using a large multilocus dataset from hundreds of samples across North America, we identified genetic clusters across the geographic range of the tiger salamander complex. These clusters often contain a mixture of paedomorphic and metamorphic taxa, indicating that geographic isolation has played a larger role in lineage divergence than paedomorphosis in this system. This conclusion is bolstered by geography-informed analyses indicating no effect of life history strategy on population genetic differentiation and by model-based population genetic analyses demonstrating gene flow between adjacent metamorphic and paedomorphic populations. This fine-scale genetic perspective on life history variation establishes a framework for understanding how plasticity, local adaptation, and gene flow contribute to lineage divergence. Many members of the tiger salamander complex are endangered, and the Mexican axolotl is an important model system in regenerative and biomedical research. Our results chart a course for more informed use of these taxa in experimental, ecological, and conservation research.