Influence of orthodontic appliance type on salivary parameters during treatment

ABSTRACT Objectives To evaluate the effect of orthodontic appliances on physicochemical, biochemical, and oxidative stress changes in salivary parameters during treatment. Materials and Methods A cohort study was conducted with 112 healthy patients. Salivary samples were taken at baseline, 1 month, and 9 months after placement of the orthodontic appliances used in treatment. Results A statistically significant difference was observed in certain examined salivary parameters, including enzymes, electrolytes, and oxidative stress markers. Conclusions The use of aligners had a lower prevalence of disturbing salivary parameters. Orthodontist must consider these changes to prevent the occurrence of white spot lesions.

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Abnormal Levels of Inflammatory and Oxidative Stress Markers in Patients with Arterial Hypertension and Diabetes Mellitus

Journal of Biomedical and Clinical Research ◽

10.1515/jbcr-2015-0107 ◽

2013 ◽

Vol 6 (2) ◽

pp. 89-93

Author(s):

Maya P. Danovska ◽

Margarita L. Alexandrova ◽

Irena I. Gencheva

Keyword(s):

Oxidative Stress ◽

Diabetes Mellitus ◽

Risk Factors ◽

Arterial Hypertension ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Cardiovascular Morbidity And Mortality ◽

Significant Difference ◽

Traditional Risk Factors ◽

And Oxidative Stress

Summary Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.

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The association between irisin levels, element distribution and oxidative stress markers in adolescent swimmers

Hormone Molecular Biology and Clinical Investigation ◽

10.1515/hmbci-2018-0006 ◽

2018 ◽

Vol 0 (0) ◽

Cited By ~ 1

Author(s):

Muaz Belviranli ◽

Nilsel Okudan ◽

Nuran Karakuyu

Keyword(s):

Oxidative Stress ◽

Exercise Training ◽

Venous Blood ◽

Element Distribution ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Significant Difference ◽

And Gender ◽

Antioxidant Effects ◽

And Oxidative Stress

Abstract The objective of this investigation was to compare irisin concentration and its relation with oxidative stress markers, antioxidant enzymes and element levels in both male adolescent swimmers and sedentary controls. Twelve male swimmers aged between 11 and 18 years, who performed regular swimming training for at least 2 years and 12 age- and gender-matched sedentary controls participated in this study. After anthropometric measurements were performed, fasting venous blood samples were taken at rest. Irisin, malondialdehyde (MDA) as a marker of oxidative stress, superoxide dismutase (SOD) as a marker of antioxidant enzyme and elements (Zn, Cu, Se, Cr, Ni, Al, Fe) were analyzed in these samples. MDA levels were lower but Zn levels and Zn/Cu ratio were higher in the swimmers than in sedentary controls (p < 0.05). There was no statistically significant difference in the irisin levels and SOD activities between the groups (p > 0.05). The results of the current study suggested that exercise training has antioxidant effects and may reduce oxidative damage. Exercise training has also limited effects on irisin levels in the adolescents.

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Effects of Leaf Extract of Cnidoscolus aconitifolius on Serum Lipids and Oxidative Stress Markers of Male Wistar Rats

Asian Journal of Biochemistry, Genetics and Molecular Biology ◽

10.9734/ajbgmb/2020/v5i130120 ◽

2020 ◽

pp. 47-52

Author(s):

Ijeoma Ezebuiro ◽

Chibuike Obiandu ◽

Friday Saronee ◽

Adesua C. Obiandu

Keyword(s):

Oxidative Stress ◽

Wistar Rats ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Cnidoscolus Aconitifolius ◽

Significant Difference ◽

Male Wistar Rats ◽

And Oxidative Stress

Introduction: Cnidoscolus aconitifolius is considered to be an important and effective medicinal plant in folklore remedies where it has been applied as an alternative therapy for the treatment of various ailments. Aim: The present study aims to determine the effects of Cnidoscolus aconitifolius on lipid profile and some oxidative stress markers of male Wistar rats. Methodology: A total of 15 male wistar rats were procured for the study and randomly assigned into three groups of 5 rats each. Group 1 served as control and received distilled water only. Group 2 received 200 mg/kg and group 3 received 400mg/kg of the hydromethanolic (1:4) extract of Cnidoscolus aconitifolius which was administered as single daily dose using oral cannula. On completion of treatment, blood samples were collected by cardiac puncture for determination of some serum lipid parameters and oxidative stress markers. Results: Results showed that there were no significant difference in the serum level of total cholesterol, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol at both doses of the extract, compared to control. However, compared to control, there was a significant (p<0.05) increase in the activity of superoxide dismutase and glutathione reductase but significant reduction in malondialdehyde level. The catalase enzyme activity was not significant. Conclusion: The result obtained suggest that the extract may be useful in reducing oxidative stress by improving some antioxidant enzyme activities and may also prevent cell death due to lipid peroxidation.

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Leukocytes Count and Oxidative Stress Markers in Blood and Follicular Fluid in Infertile Women Undergo Intracytoplasmic Sperm Injection (Ic

Indian Journal Of Applied Research ◽

10.15373/2249555x/august2014/125 ◽

2011 ◽

Vol 4 (8) ◽

pp. 483-485

Author(s):

Sami R Al-Katib ◽

◽

Basima Sh AlGhazali ◽

Ban J Edan

Keyword(s):

Oxidative Stress ◽

Follicular Fluid ◽

Intracytoplasmic Sperm Injection ◽

Oxidative Stress Markers ◽

Infertile Women ◽

Stress Markers ◽

And Oxidative Stress

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Comparison of Salivary Antioxidants and Oxidative Stress Status in Gestational Diabetes Mellitus and Healthy Pregnant Women

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1568026620666201022151059 ◽

2020 ◽

Vol 20 ◽

Author(s):

Fatemeh Ahmadi-Motamayel ◽

Shima Fathi ◽

Mohammad Taghi Goodarzi ◽

Shiva Borzouei ◽

Jalal Poorolajal ◽

...

Keyword(s):

Oxidative Stress ◽

Diabetes Mellitus ◽

Gestational Diabetes ◽

Pregnant Women ◽

Oxidative Stress Markers ◽

Blood Samples ◽

Stress Markers ◽

Total Antioxidant ◽

Total Oxidative Stress ◽

And Oxidative Stress

Background: One of the most common complications of pregnant women is gestational diabetes mellitus (GDM). Oxidative stress can play an important role in GDM. Objective: The aim of this study was to evaluate salivary antioxidants and oxidative stress markers in GDM. Method: Twenty pregnant women with GDM and 20 healthy pregnant women with normal blood glucose test participated in this study. Five mL of unstimulated saliva samples were collected. Spectrophotometric assay was carried out for sialochemical analysis. Stata software was used for data analysis. Results: The GDM group exhibited no significant difference in salivary total antioxidant capacity and malondialdehyde compared to the healthy control group. All of antioxidants markers, the uric acid, total antioxidant, peroxidase and catalase, decreased in GDM group that the difference of peroxidase and catalase was statistically significant. All of oxidative stress markers, the salivary malondyaldehid, total oxidative stress and total thiol, increased in GDM group. GDM group exhibited significantly higher salivary total oxidative stress levels. Conclusion: Catalase level was significantly lower and total oxidative stress was significantly higher. These two markers might have significant importance and might exhibit early changes compared to other factors in GDM. . Some of salivary antioxidants might have diagnostic, prognostic or therapeutic implications in GDM. Other studies with large sample size on salivary and blood samples need to be done to confirm this properties and salivary samples using instead of blood samples in GDM biomarkers changes.

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Evaluation of Salivary Antioxidants and Oxidative Stress Markers in Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530319666191016103222 ◽

2020 ◽

Vol 20 (4) ◽

pp. 584-590 ◽

Cited By ~ 1

Author(s):

Shima Fathi ◽

Shiva Borzouei ◽

Mohammad Taghi Goodarzi ◽

Jalal Poorolajal ◽

Fatemeh Ahmadi-Motamayel

Keyword(s):

Oxidative Stress ◽

Diabetes Mellitus ◽

Control Group ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Type 2 Dm ◽

Patients With Diabetes ◽

The Difference ◽

And Oxidative Stress

Background: Diabetes Mellitus (DM) is a progressive metabolic disorder. Objective: The aim of this study was to investigate the relationship between antioxidant and oxidative stress markers in the saliva of patients with type 2 DM and a healthy control group. Methods: In this study, 20 patients with diabetes and 20 healthy individuals were evaluated. Salivary antioxidants markers consisted of total antioxidant capacity (TAC), uric acid (UA), peroxidase and catalase. Oxidative stress markers included total oxidant status (TOS), malondealdehyde (MDA) and total thiol (SH). Sialochemical analysis was performed with spectrophotometric assay. All the statistical analyses were conducted using STATA software. Results: TAC decreased significantly in patients with diabetes. Although salivary UA and peroxidase were lower in patients with diabetes compared to the control group, the difference was not significant. Salivary catalase in patients with diabetes was significantly lower than that in the control group. MDA and TOS exhibited significantly higher levels in type 2 DM. SH levels were slightly higher in DM. Conclusions: According to the results of the present study, there were some changes in the salivary levels of some antioxidants and oxidative stress markers in patients with type 2 DM and could be measured as an indicator of serum changes..

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