2144-PUB: Elevated Carotid Intima-Media Thickness Is an Important Predictor of Major Cardiovascular Events and All-Cause Death in Elderly Women with Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2144-PUB
Author(s):  
MARIUSZ DABROWSKI ◽  
TADEUSZ DEREZINSKI ◽  
ALEKSANDRA URUSKA ◽  
DOROTA ZOZULINSKA-ZIOLKIEWICZ
Keyword(s):  
Cardiovascular Events ◽  
Elderly Women ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Important Predictor ◽  
Media Thickness ◽  
Major Cardiovascular Events

scholarly journals Clinical and therapeutic value of carotid intima-media thickness

2015 ◽  
Vol 76 (3) ◽  
Author(s):  
Enrico Vassallo ◽  
Francesca Musella ◽  
Susanna Mosca ◽  
Laura Casaretti ◽  
Roberto Formisano ◽  
...  
Keyword(s):  
Cardiovascular Events ◽  
Intima Media Thickness ◽  
Surrogate Endpoint ◽  
Carotid Intima Media Thickness ◽  
Risk Level ◽  
Media Thickness ◽  
Cardiovascular Therapy ◽  
Inter Observer Variability ◽  
The Status ◽  
Prevention Studies

Carotid Intima Media Thickness (IMT) has been widely used to predict cardiovascular events in primary and secondary prevention studies. Yet, the power of IMT to reclassify risk level on top of conventional risk assessment based on classical risk factors remains unsettled. In fact, recent data indicate that the prognostic power of IMT is lower than that provided by the identification of carotid plaques. The role of IMT as surrogate endpoint to assess the efficacy of cardiovascular protective therapies is also still debated. In fact, no studies have ever been designed and powered to show a relationship between changes in carotid IMT during follow-up and cardiovascular events. Recently, two metaanalysis of trials using IMT as surrogate endpoint failed to demonstrate an association between IMT regression and cardiovascular events. The reasons for the lack of predictive role for changes in IMT are uncertain. It has been shown that IMT is not a pure atherosclerotic index, being substantially affected by age and hemodynamic factors including blood pressure and vessel wall shear stress. In addition, the status of carotid vessels does not strictly reflect that of coronary arteries. Finally, intra and inter-observer variability of measurements may further limit the association between IMT changes in individual patients and cardiovascular risk. Thus, IMT represents a valuable risk marker in population studies but its role for tailoring cardiovascular therapy in clinical practice remains currently uncertain.

Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes

2020 ◽  
Vol 34 (10) ◽  
pp. 107681
Author(s):  
Karoline Winckler ◽  
Birger Thorsteinsson ◽  
Niels Wiinberg ◽  
Andreas Kryger Jensen ◽  
Louise Lundby-Christensen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Events ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

scholarly journals Does Carotid Intima-Media Thickness Regression Predict Reduction of Cardiovascular Events?

2010 ◽  
Vol 56 (24) ◽  
pp. 2006-2020 ◽  
Author(s):  
Pierluigi Costanzo ◽  
Pasquale Perrone-Filardi ◽  
Enrico Vassallo ◽  
Stefania Paolillo ◽  
Paolo Cesarano ◽  
...  
Keyword(s):  
Cardiovascular Events ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

Increased carotid intima–media thickness predicts cardiovascular events in aortic coarctation

2014 ◽  
Vol 176 (3) ◽  
pp. 776-781 ◽  
Author(s):  
Paul Luijendijk ◽  
Huangling Lu ◽  
Frederike B. Heynneman ◽  
Roeland Huijgen ◽  
Eric E. de Groot ◽  
...  
Keyword(s):  
Aortic Coarctation ◽  
Cardiovascular Events ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

Association of Inflammatory Markers and Carotid Intima-Media Thickness with the Risk of Cardiovascular Events in High-Risk Patients

2010 ◽  
Vol 30 (2) ◽  
pp. 180-187 ◽  
Author(s):  
Shuhei Okazaki ◽  
Shigetaka Furukado ◽  
Yuko Abe ◽  
Makiko Tanaka ◽  
Kaori Miwa ◽  
...  
Keyword(s):  
High Risk ◽  
Inflammatory Markers ◽  
Cardiovascular Events ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
High Risk Patients ◽  
Media Thickness ◽  
Risk Patients
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