scholarly journals Maternal Gestational Diabetes Mellitus, Type 1 Diabetes, and Type 2 Diabetes During Pregnancy and Risk of ADHD in Offspring

Diabetes Care ◽  
2018 ◽  
Vol 41 (12) ◽  
pp. 2502-2508 ◽  
Author(s):  
Anny H. Xiang ◽  
Xinhui Wang ◽  
Mayra P. Martinez ◽  
Darios Getahun ◽  
Kathleen A. Page ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type

scholarly journals High Prevalence of Type 2 Diabetes and Pre-Diabetes in Adult Offspring of Women With Gestational Diabetes Mellitus or Type 1 Diabetes: The role of intrauterine hyperglycemia

Diabetes Care ◽  
2007 ◽  
Vol 31 (2) ◽  
pp. 340-346 ◽  
Author(s):  
T. D. Clausen ◽  
E. R. Mathiesen ◽  
T. Hansen ◽  
O. Pedersen ◽  
D. M. Jensen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Adult Offspring ◽  
High Prevalence

scholarly journals Most Women with Previous Gestational Diabetes Mellitus Have Impaired Glucose Metabolism after a Decade

2018 ◽  
Vol 19 (12) ◽  
pp. 3724
Author(s):  
Wahlberg Jeanette ◽  
Ekman Bertil ◽  
Arnqvist Hans
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Glucose Metabolism ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Gestational Diabetes Mellitus ◽  
Impaired Glucose Metabolism

Of 1324 women diagnosed with gestational diabetes mellitus (GDM) in Sweden, 25% reported >10 years after the delivery that they had developed diabetes mellitus. We assessed the long-term risk of all glucose metabolic abnormalities in a subgroup of these women. Women (n = 51) previously diagnosed with GDM by capillary blood glucose ≥9.0 mmol/L (≈plasma glucose ≥10.0 mmol/L) after a 2 h 75 g oral glucose tolerance test (OGTT) were included. All underwent a clinical and biochemical evaluation, including a second 2 h 75 g OGTT. Individuals with known type 1 diabetes were excluded. At the follow-up, 12/51 (24%) reported previously diagnosed type 2 diabetes. Another four cases were diagnosed after the second OGTT, increasing the prevalence to 16/51 cases (31%). Impaired fasting plasma glucose (IFG) was diagnosed in 13/51 women and impaired glucose tolerance (IGT) in 10/51 women, leaving only 12 women (24%) with normal glucose tolerance. In addition, 2/51 women had high levels of glutamic acid decarboxylase (GAD) antibodies; of these, one woman classified as type 2 diabetes was reclassified as type 1 diabetes, and the second GAD-positive woman was diagnosed with IGT. Of the women diagnosed with GDM by a 2 h 75 g OGTT, a large proportion had impaired glucose metabolism a decade later, including type 1 and type 2 diabetes.

Placental morphology in different types of diabetes mellitus

2021 ◽  
Vol 70 (2) ◽  
pp. 13-26
Author(s):  
Roman V. Kapustin ◽  
Ekaterina V. Kopteyeva ◽  
Tatyana G. Tral ◽  
Gulrukhsor Kh. Tolibova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Type 1 Diabetes Mellitus ◽  
Different Types

AIM: The aim of this study was to compare placental morphological features from women with different types of diabetes mellitus considering method of DM correction. MATERIALS AND METHODS: A retrospective, single-center, cohort study was carried out. We analyzed morphological examination results of 3300 placentas, which made uр the following comparison groups: type 1 diabetes mellitus on continuous subcutaneous insulin infusion (n = 60), type 1 diabetes mellitus on multiple subcutaneous insulin injections (n = 446), type 2 diabetes mellitus on diet (n = 95), type 2 diabetes mellitus on insulin therapy (n = 134), gestational diabetes mellitus on diet (n = 1652), gestational diabetes mellitus on insulin therapy (n = 735), preeclampsia (n = 39), and the control group (n = 139). The examined placentas were weighed, with their sizes (two diameters and thickness), cotyledon structure and defects assessed. We determined the umbilical cord junction and external characteristics of extraembryonic membranes. Fragments of the placenta (5 pieces) were fixed in 10% neutral buffered formalin (pH 7.2), processed with the Leica TP1020 tissue processor and embedded in paraffin. Histological sections (3-4 m thick) were prepared and stained with hematoxylin-eosin. Statistical analysis was performed using the SPSS 23.0 and GraphPad Prism 8.0 software. RESULTS: Following characteristics were typical for all types of diabetes mellitus: increased placental mass metrics, chronic placental insufficiency, dissociated villous maturation disorder with prevalent immaturity, as well as involutive-dystrophic and circulatory disorders of varying severity. Placentas from women with type 1 diabetes mellitus had the specific sings: the predominance of intermediate immature villi and stem villi stromal fibrosis. The frequency of placental infarcts and fibrinoid content in the intervillous space were comparable to those in placentas from women with type 2 diabetes mellitus. Inflammatory changes and moderate placental calcification were most consistently associated with type 2 diabetes mellitus, while gestational diabetes mellitus was characterized by soft damages. Placentas with preeclampsia showed higher prevalence of premature villous maturation, compensated placental insufficiency, and fibrinoid depositions in the intervillous and subchorionic spaces. CONCLUSIONS: Understanding relationships between placental histological features and clinical aspects of diabetes mellitus makes it possible not only to clarify the pathophysiological processes occurring in this pathology but also to optimize the algorithm for the rational management of the neonatal period of children from mothers with diabetes mellitus.

scholarly journals A case of euglyacemic diabetic ketoacidosis in a patient with gestational diabetes mellitus

2014 ◽  
Vol 7 (4) ◽  
pp. 174-176 ◽  
Author(s):  
UM Graham ◽  
IE Cooke ◽  
DR McCance
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Plasma Glucose ◽  
Fetal Movement ◽  
Intravenous Dextrose

A 30-year old woman at 30 weeks gestation with insulin-controlled gestational diabetes was admitted with nausea and vomiting. Plasma glucose was 3.3 mmol/l with pH 7.23 and raised capillary ketones at 6.1 mmol/l. She was diagnosed with euglycaemic diabetic ketoacidosis. Cardiotocography showed good fetal movement and accelerations. She was given intramuscular betamethasone and started on intravenous dextrose, insulin and 0.9% saline with potassium chloride with resolution of ketosis. Euglycaemic diabetic ketoacidosis has been reported during pregnancy in patients with type 1 and type 2 diabetes. We believe that this is a report of such an occurrence in a patient with gestational diabetes.

scholarly journals Association between periodontitis, gestational diabetes mellitus and diabetes mellitus type 1 and 2 in pregnant women

2015 ◽  
Vol 3 (1) ◽  
pp. 18
Author(s):  
Rafael Paschoal Esteves Lima ◽  
Fernando Oliveira Costa ◽  
Luis Otávio Miranda Cota ◽  
Renata Magalhães Cyrino
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type

scholarly journals Fetal Macrosomia in the Diabetic Woman

2012 ◽  
Vol 19 (1) ◽  
pp. 41-48
Author(s):  
Marlena Pascu ◽  
Ruxandra Miulescu ◽  
C. Ionescu-Tîrgoviste
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
General Population ◽  
Gestational Diabetes ◽  
Fetal Macrosomia ◽  
Diabetic Woman

Fetal Macrosomia in the Diabetic WomanDiabetes mellitus complicates up to 10% of pregnancies, while in Romania the incidence is this under 5%. In most of the cases we are talking about gestational diabetes, while only in 0.1 - 0.3% of the cases, the diabetes was pregestational (mainly Type 1 diabetes and rarely Type 2 diabetes or Mody). The study we conducted concerned the incidence of macrosomia in the general population; in the study we investigated 3,000 pregnant patients who gave birth in the Unit of Obstetrics & Gynecology of ‘Dr Cantacuzino’ Hospital from 13th January 2007 to 30th March 2010. The 7.1% of incidence of diabetes mellitus highlighted by the study which aimed to trace gestational diabetes conducted in 2007-2010 period with the assistance of the ‘Dr Cantacuzino’ Hospital, represents just the tip of the iceberg. The positive diagnosis of gestational diabetes identified not only women who had diabetes mellitus pre-existing the pregnancy, without their being aware of it, but also women with a pathology of carbohydrate metabolism who will in the future run a higher risk of developing type 2 diabetes mellitus.

Prevalence of type 2 Diabetes in Sweden

1983 ◽  
Vol 104 (4_Suppl) ◽  
pp. S27-S29
Author(s):  
Gunnar Sartor
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Risk Group ◽  
Risk Groups ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Swedish Population ◽  
Prevalence Of Diabetes Mellitus

ABSTRACT. Studies on the prevalence of diabetes mellitus, type 1 and type 2, in Sweden covering four decades give figures ranging from 0.35 % to 2.3 %. Figures are assumed to reflect type 2 diabetes in the majority of cases. In the most recent study the prevalence is 2.08 % for males and 1.95 % for females after standardization to total Swedish population. The disease becomes very common above the age of 60 (5.7 % or more). High risk groups suitable for screening are reviewed. Key words: diabetes mellitus, type 2 prevalence risk group screening procedure

Transcriptome meta-analysis of peripheral lymphomononuclear cells indicates that gestational diabetes is closer to type 1 diabetes than to type 2 diabetes mellitus

2013 ◽  
Vol 40 (9) ◽  
pp. 5351-5358 ◽  
Author(s):  
C. V. A. Collares ◽  
A. F. Evangelista ◽  
D. J. Xavier ◽  
P. Takahashi ◽  
R. Almeida ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Meta Analysis
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