scholarly journals Sensitization to Skin-associated Microorganisms in Adult Patients with Atopic Dermatitis is of Importance for Disease Severity

2013 ◽  
Vol 93 (3) ◽  
pp. 340-345 ◽  
Author(s):  
A Sonesson ◽  
J Bartosik ◽  
J Christiansen ◽  
I Roscher ◽  
F Nilsson ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Adult Patients

Salivary chromogranin A levels correlate with disease severity but do not reflect anxiety or personality of adult patients with atopic dermatitis

2017 ◽  
Vol 44 (8) ◽  
pp. 920-926 ◽  
Author(s):  
Sakae Kaneko ◽  
Lijuan Liu ◽  
Takeyasu Kakamu ◽  
Masako Minami-Hori ◽  
Eishin Morita
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Chromogranin A ◽  
Adult Patients

Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section II: Tools for Assessing the Severity of Atopic Dermatitis

2018 ◽  
Vol 22 (1_suppl) ◽  
pp. 10S-16S ◽  
Author(s):  
Melinda J. Gooderham ◽  
Robert Bissonnette ◽  
Parbeer Grewal ◽  
Perla Lansang ◽  
Kim A. Papp ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Life Quality ◽  
Severity Index ◽  
Adult Patients ◽  
Physician Global Assessment ◽  
Atopic Dermatitis Severity ◽  
Patient Reported

Clinicians rely on clinical measures to define the severity of atopic dermatitis and assess outcomes of therapy. These measures can be objective (ie, physician assessments of disease severity) or subjective (ie, patient-reported symptoms and quality of life outcomes). In this review, the most commonly used tools for assessing atopic dermatitis severity in adult patients are presented and compared. These include Eczema Area and Severity Index (EASI); SCORing Atopic Dermatitis (SCORAD); Physician Global Assessment (PGA); body surface area (BSA); Atopic Dermatitis Severity Index (ADSI); Six Area, Six Sign Atopic Dermatitis (SASSAD); Patient Oriented Eczema Measure (POEM); Dermatology Life Quality Index (DLQI); and pruritus Numerical Rating Scale (NRS). Available severity strata for the tools are summarized, although the use of severity strata in clinical practice is not recommended. Since both objective and subjective assessments of disease severity are important to assess, consideration of clinical characteristics such as disease recurrence or persistence, as well as location of the affected areas, should be considered in the overall judgement of disease severity and consideration of therapy choice.

scholarly journals The Comparative Study of Atopic Dermatitis and Chronic Hand Eczema Clinical Course in Adults after Acute Relapse Treatment

2021 ◽  
pp. 373-379
Author(s):  
Aleksandruk Oleksandr Dmytrovych ◽  
Stepanenko Roman Leonidovich ◽  
Ali Mohammed ◽  
Stepanenko Viktor Ivanovich ◽  
Tetiana Konovalova ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Hand Eczema ◽  
Skin Care ◽  
Adult Patients ◽  
Sample Population ◽  
Relapse Treatment ◽  
Chronic Hand Eczema ◽  
Acute Relapse ◽  
Anti Inflammatory

Aims: To evaluate Atopic dermatitis (AD) and Chronic hand eczema (CHE) course in adults after discontinuation of acute or sub acute relapse treatment. Study Design: three groups of adult patients that finished standard treatment for relapse of AD and CHE were followed up within 24 weeks of period to check disease severity, itch intensity and skin management effectiveness. Place and Duration of Study Sample: population of Ivano-Frankivsk region of Ukraine September 2015 – May 2021. Methods: 155 patients (51 females and 104 males; age between 20 and 50 years) with AD or CHE were enrolled in the study. The patients were randomized into three study groups depending on diagnosis. SCORAD index was used to assess disease severity, visual analog scale (VAS) was used to assess skin itch intensity. Frequency of disease treatment re-start with topical or systemic anti-inflammatory drugs as well as patients’sintention to ask for a treatment were calculated. Results: Results of our study have shown that cases of new disease worsening occured within nearest 24 weeks after AD and CHE aggravation treatment discontinuation and are quite frequent despite appropriate skin care. Conclusion: part of adult patients continues suffering from skin itch or mild skin lesions within nearest 24 weeks after discontinuation of intensive treatment of AD or CHE relapse. Prescription of antihistamines and/or topical anti-inflammatory treatment in addition to generally recommended skin care with emollients is crucial for patients with new worsening of the disease. Among patients with a new signs of worsening a part would unlikely ask for a new treatment immediately unless this worsening is moderate or severe.

scholarly journals US health care utilization and costs in adult patients with atopic dermatitis by disease severity

2022 ◽  
Vol 28 (1) ◽  
pp. 69-77
Author(s):  
Xin Wang ◽  
Natalie N Boytsov ◽  
Magdaliz Gorritz ◽  
William N Malatestinic ◽  
Orin M Goldblum ◽  
...  
Keyword(s):  
Health Care ◽  
Atopic Dermatitis ◽  
Health Care Utilization ◽  
Disease Severity ◽  
Adult Patients ◽  
Care Utilization

scholarly journals Comorbidities and treatment patterns in adult patients with atopic dermatitis: results from a nationwide multicenter study

2021 ◽  
Author(s):  
A. Campanati ◽  
T. Bianchelli ◽  
R. Gesuita ◽  
C. Foti ◽  
G. Malara ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Laboratory Data ◽  
Adult Patients ◽  
Severe Atopic Dermatitis ◽  
Inflammatory Disorder ◽  
Treatment Type ◽  
Close Relationship ◽  
Metabolic Conditions ◽  
Metabolic Comorbidities

AbstractAdult atopic dermatitis (adult AD) is a systemic inflammatory disorder, whose relationship with immune-allergic and metabolic comorbidities is not well established yet. Moreover, treatment of mild-to-moderate and severe atopic dermatitis needs standardization among clinicians. The aim of this study was to evaluate the distribution of comorbidities, including metabolic abnormalities, rhinitis, conjunctivitis, asthma, alopecia and sleep disturbance, according to severity of adult AD, and describe treatments most commonly used by Italian dermatologists. Retrospective, observational, nationwide study of adult patients over a 2-year period was performed. Clinical and laboratory data were obtained through review of medical records of patients aged ≥ 18 years, followed in 23 Italian National reference centres for atopic dermatitis between September 2016 and September 2018. The main measurements evaluated were disease severity, atopic and metabolic comorbidities, treatment type and duration. Six-hundred and eighty-four adult patients with AD were included into the study. Atopic, but not metabolic conditions, except for hypertension, were significantly associated with having moderate-to-severe AD in young adult patients. Disease duration was significantly associated with disease severity. Oral corticosteroids and cyclosporine were the most widely used immunosuppressant. Our study seems confirm the close relationship between adult AD and other atopic conditions, further long-term cohort studies on patients affected by adult AD need to be performed to evaluate the complex relationship between adult AD disease severity and metabolic comorbidities.

Sign in / Sign up

Export Citation Format

Share Document