Is CRX Protein a Useful Marker in Differential Diagnosis of Tumors of the Pineal Region?

2014 ◽  
Vol 17 (2) ◽  
pp. 85-88 ◽  
Author(s):  
Antonelli Manila ◽  
Novello Mariangela ◽  
Lauriola Libero ◽  
Gianno Francesca ◽  
Buttarelli Francesca Romana ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Protein A ◽  
Pineal Region

Pineal region masses: differential diagnosis.

Radiographics ◽  
1992 ◽  
Vol 12 (3) ◽  
pp. 577-596 ◽  
Author(s):  
J G Smirniotopoulos ◽  
E J Rushing ◽  
H Mena
Keyword(s):  
Differential Diagnosis ◽  
Pineal Region

scholarly journals Infantile colic from the perspective of evidence-based medicine: prevalence, principles of differential diagnosis and diet therapy algorithm

2019 ◽  
pp. 147-155
Author(s):  
М. М. Gurova
Keyword(s):  
Nervous System ◽  
Differential Diagnosis ◽  
Breast Milk ◽  
Protein A ◽  
Diet Therapy ◽  
Intestinal Microbiome ◽  
Therapy Algorithm ◽  
Positive Effects ◽  
Hydrolyzed Protein ◽  
Functional Immaturity

The article presents data on the prevalence of infant colic, etiological factors, diagnostic criteria, differential diagnosis and therapy with justification of approaches to the choice of formula in children on artificial feeding. When choosing a formula, it is necessary to take into account the compositional features aimed at overcoming the functional immaturity of the gastrointestinal tract, enteric nervous system, and the ongoing formation of the intestinal microbiome – the presence of a partially hydrolyzed protein, a reduced lactose content, the presence of prebiotics (fructooligosaccharides) and probiotics. The formula Similac Comfort is fully compliant. This formula additionally contains oligosaccharide of the breast milk 2 fucosillactose (2’-FL), 0.2 g / l – identical to that found in breast milk, which has proven positive effects in the form of an immunomodulating effect, anti-infectious effect, is involved in the regulation of growth and maturation of intestinal epithelial cells, in the development of the nervous system.

scholarly journals Central neurocytomas of uncommon locations: report of two cases

2006 ◽  
Vol 64 (4) ◽  
pp. 1015-1018 ◽  
Author(s):  
Francinaldo Lobato Gomes ◽  
Luciano Ricardo França ◽  
Samuel Tau Zymberg ◽  
Sérgio Cavalheiro
Keyword(s):  
Differential Diagnosis ◽  
Intracranial Pressure ◽  
Obstructive Hydrocephalus ◽  
Signs And Symptoms ◽  
Pineal Region ◽  
Additional Treatment ◽  
Third Ventriculostomy ◽  
Increased Intracranial Pressure ◽  
The Brain ◽  
Uncommon Location

We report two patients with central neurocytomas at an uncommon location in the brain. The first, a 58-year-old man presenting with signs and symptoms of increased intracranial pressure, had a tumor located at the pineal region. The second, a 21-year-old woman with tumor in the aqueductal region had worsening migraine-like headaches and diplopia. Both patients had obstructive hydrocephalus treated by neuroendoscopic third ventriculostomy and biopsy of the tumors. No additional treatment was done. We conclude that neurocytomas should be considered in the differential diagnosis of tumors located in the pineal and aqueductal regions.

Papillary Tumor of the Pineal Region with Parinaud Syndrome: A Case Report

2020 ◽  
Vol 16 (8) ◽  
pp. 1044-1047
Author(s):  
Lale Damgacı ◽  
Büşra Hayat ◽  
Servet Güreşçi
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Soft Tissue ◽  
World Health Organisation ◽  
Pineal Region ◽  
World Health ◽  
Pathology Report ◽  
Mri Findings ◽  
Papillary Tumor ◽  
Intravenous Contrast

Background: Less than 1% of all intracranial tumors are in the pineal region. Papillary tumor of the pineal region is considered one of four pineal parenchymal tumors according to the 2007 World Health Organisation classification of central nervous system tumors. It is mostly seen in the middle age and it is rare under the age of 17 in the literature. In this report, we aim to present a case with papillary tumor of the pineal region with both CT and MRI findings, and discuss the differential diagnosis. Case report: A 17-year-old female patient who underwent a treatment of ventriculoperitoneal shunt due to hydrocephalus 18 months ago applied to the neurosurgery clinic with nausea, vomiting, sensorineural hearing loss and Parinaud syndrome continuing through 1 month. Computed tomography (CT) and magnetic resonance imaging (MRI) have been applied. A 58x31x38 mm mass with cystic and mild hyperdense soft tissue components was observed in the localization of pineal gland and posterior comissure on non-enhanced CT. MRI examination revealed that the mass filled the pineal region, contained solid and large cystic components, and hyperintense on T1-weighted images. After intravenous contrast media injection, the mass enhanced more peripherally. DW-MRI showed that there is a diffusion restriction in some parts of the soft tissue components. The mass was totally resected, and pathology report revealed that it is a papillary tumor of the pineal region. Conclusion: When a T1-weighted hyperintense and CT hyperdense mass with cystic and solid components is seen in the pineal region, even if it is rare, papillary tumor should also be considered in the differential diagnosis after exclusion of other hyperintense lesions in T1-weighted imaging.

scholarly journals Diffusion-weighted MR images and pineoblastoma: diagnosis and follow-up

2008 ◽  
Vol 66 (1) ◽  
pp. 64-68 ◽  
Author(s):  
Emerson L. Gasparetto ◽  
L. Celso Hygino da Cruz Jr ◽  
Thomas M. Doring ◽  
Bertha Araújo ◽  
Mário Alberto Dantas ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Mr Imaging ◽  
Poor Prognosis ◽  
Pineal Region ◽  
Restricted Diffusion ◽  
Mr Images ◽  
Surgical Biopsy ◽  
Pineal Tumors ◽  
Diffusion Weighted

Pineoblastomas are uncommon pineal tumors, which demonstrate rapid growing and poor prognosis. We report the case of a 43-year-old man with an enhancing pineal region mass, which showed restriction of the diffusion on diffusion-weighted (DW) MR images. The surgical biopsy defined the diagnosis of pineoblastoma and the therapy was initiated with radiation and chemotherapy. Three months later, the follow-up MR imaging showed areas suggestive of necrosis and the DW images demonstrate no significant areas of restricted diffusion. The differential diagnosis of pineal region masses that could show restriction of diffusion is discussed.

Papillary pineocytoma

1990 ◽  
Vol 73 (1) ◽  
pp. 135-137 ◽  
Author(s):  
Jesús Vaquero ◽  
Santiago Coca ◽  
Roberto Martínez ◽  
Jorge Escandón
Keyword(s):  
Differential Diagnosis ◽  
Pineal Region ◽  
Histological Type ◽  
Content Type ◽  
Fine Print

✓ A case of papillary pineocytoma is presented. It is necessary to be aware of this unusual histological type of pineocytoma in order to make a differential diagnosis among other types of papillary tumors that arise in the pineal region.

scholarly journals Precision of preoperative diagnosis in patients with brain tumor – A prospective study based on “top three list” of differential diagnosis for 1061 patients

2020 ◽  
Vol 11 ◽  
pp. 55 ◽  
Author(s):  
Kazunori Arita ◽  
Makiko Miwa ◽  
Manoj Bohara ◽  
FM Moinuddin ◽  
Kiyohisa Kamimura ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Brain Tumor ◽  
Preoperative Diagnosis ◽  
Preoperative Evaluation ◽  
Correct Diagnosis ◽  
Rate Sensitivity ◽  
Pineal Region ◽  
Surgical Strategy ◽  
Pineal Region Tumors ◽  
First Diagnosis

Background: Accurate diagnosis of brain tumor is crucial for adequate surgical strategy. Our institution follows a comprehensive preoperative evaluation based on clinical and imaging information. Methods: To assess the precision of preoperative diagnosis, we compared the “top three list” of differential diagnosis (the first, second, and third diagnoses according to the WHO 2007 classification including grading) of 1061 brain tumors, prospectively and consecutively registered in preoperative case conferences from 2010 to the end of 2017, with postoperative pathology reports. Results: The correct diagnosis rate (sensitivity) of the first diagnosis was 75.8% in total. The sensitivity of the first diagnosis was high (84–94%) in hypothalamic-pituitary and extra-axial tumors, 67–75% in intra-axial tumors, and relatively low (29–42%) in intraventricular and pineal region tumors. Among major three intra-axial tumors, the sensitivity was highest in brain metastasis: 83.8% followed by malignant lymphoma: 81.4% and glioblastoma multiforme: 73.1%. Sensitivity was generally low (≦60%) in other gliomas. These sensitivities generally improved when the second and third diagnoses were included; 86.3% in total. Positive predictive value (PPV) was 76.9% in total. All the three preoperative diagnoses were incorrect in 3.4% (36/1061) of cases even when broader brain tumor classification was applied. Conclusion: Our institutional experience on precision of preoperative diagnosis appeared around 75% of sensitivity and PPV for brain tumor. Sensitivity improved by 10% when the second and third diagnoses were included. Neurosurgeons should be aware of these features of precision in preoperative differential diagnosis of a brain tumor for better surgical strategy and to adequately inform the patients.

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