Study on regulation of adipokines on body fat distribution and its correlation with metabolic syndrome in type 2 diabetes mellitus

2019 ◽  
Vol 44 (3) ◽  
Author(s):  
Xiaoxi Liu ◽  
Xiaojuan Li ◽  
Changhui Li ◽  
Chengjun Gong ◽  
Songyan Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution

Effects of rosiglitazone on body fat distribution and insulin sensitivity in Korean type 2 diabetes mellitus patients

Metabolism ◽  
2008 ◽  
Vol 57 (4) ◽  
pp. 479-487 ◽  
Author(s):  
You-Cheol Hwang ◽  
Eun Young Lee ◽  
Won Jae Lee ◽  
Bong Soo Cha ◽  
Kun-Ho Yoon ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Sensitivity ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Korean Type

scholarly journals Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus

Circulation ◽  
2017 ◽  
Vol 135 (24) ◽  
pp. 2373-2388 ◽  
Author(s):  
Caroline E. Dale ◽  
Ghazaleh Fatemifar ◽  
Tom M. Palmer ◽  
Jon White ◽  
David Prieto-Merino ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Coronary Heart Disease ◽  
Type 2 Diabetes Mellitus ◽  
Heart Disease ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Stroke Subtypes

Correlation between uric acid and body fat distribution in type 2 diabetes mellitus

2016 ◽  
Vol 120 ◽  
pp. S186-S187
Author(s):  
Jung Kyu Park ◽  
Jae Wan Kwon ◽  
Eon Ju Jeon ◽  
Eui Dal Jung ◽  
Ho Sang Shon ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution

scholarly journals Visceral obesity is associated with increased soluble CD163 concentration in men with type 2 diabetes mellitus

2015 ◽  
Vol 4 (1) ◽  
pp. 27-36 ◽  
Author(s):  
Lars Peter Sørensen ◽  
Tina Parkner ◽  
Esben Søndergaard ◽  
Bo Martin Bibby ◽  
Holger Jon Møller ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Adipose Tissue ◽  
Body Fat ◽  
Fat Distribution ◽  
Normal Weight ◽  
Healthy Men ◽  
Soluble Cd163

Monocyte/macrophage-specific soluble CD163 (sCD163) concentration is associated with insulin resistance and increases with deteriorating glycemic control independently of BMI. This led to the proposal of the hypothesis that obesity-associated white adipose tissue inflammation varies between individuals. The objective was to examine the effect of male overweight/obesity and type 2 diabetes mellitus (T2DM) on associations between adiposity parameters and sCD163. A total of 23 overweight/obese non-diabetic men, 16 overweight/obese men with T2DM, and a control group of 20 normal-weight healthy men were included. Body composition and regional body fat distribution were determined by whole-body dual X-ray absorptiometry scan and abdominal computed tomography (CT) scan. Serum sCD163 concentrations were determined by ELISA. Associations between adiposity parameters and sCD163 were investigated using multiple linear regression analysis. In the normal-weight healthy men, there was no significant association between adiposity parameters and sCD163, whereas in the overweight/obese non-diabetic men, measures of general and regional adiposity were positively associated with sCD163. In the overweight/obese men with T2DM, only visceral adipose tissue (VAT) and the ratio of VAT to abdominal subcutaneous adipose tissue (SAT), a measure of relative body fat distribution between VAT and SAT depots, were positively associated with sCD163. In a multivariate analysis, including VAT, upper-body SAT, and lower-body fat, adjusted for BMI and age, VAT remained a significant predictor of sCD163 in the overweight/obese T2DM men, but not in the overweight/obese non-diabetic men. Our results indicate that VAT inflammation is exaggerated in men with T2DM, and that propensity to store excess body fat viscerally is particularly detrimental in men with T2DM.

scholarly journals Body fat distribution, cardiorespiratory fitness, and lipid profile in first degree relatives with type 2 diabetes mellitus

2019 ◽  
Vol 10 (4) ◽  
pp. 3293-3296
Author(s):  
Shaik Azmatulla ◽  
Rinku Garg ◽  
Anil Kumar Sharma ◽  
Navpret Mann
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Cardiorespiratory Fitness ◽  
Body Fat ◽  
Fat Distribution ◽  
Low Density Lipoproteins ◽  
Low Density

Evaluation of people at increased risk like first degree relatives of type 2 diabetes mellitus (FDRDM) may be useful to reduce the risk of disease progression, development, early intervention, and to take precautionary measures.  By considering the multifactorial pathophysiological changes of D.M., we have examined the body fat distribution, cardiorespiratory fitness, and lipid profile of FDRDM. Similar age, height, waist-hip ratio (WHR) in both groups, significantly higher body mass index (BMI) in FDRDM, was observed in our study. Percentage body fat and blood glucose levels in fasting were elevated considerably, and 12 min walk distance was low in FDRDM. Visceral fat was slightly high, but it was not statistically significant. In FDRDM, High-density lipoproteins (HDL) were less but not statistically significant. Significantly higher levels of  Total cholesterol (T.C.), triglycerides (TGL), low-density lipoproteins (LDL), and very-low-density lipoproteins (VLDL) were seen high in FDRDM when compared to controls. Higher body fat percentage reduced cardiorespiratory function and abnormal lipid profile in FDRDM may lead to the development of severe cardiovascular events and necessitates lifestyle modification at early phases of disease development.

Body Fat, Fat Distribution, and Psychosocial Factors Among Patients With Type 2 Diabetes Mellitus

1998 ◽  
Vol 24 (3) ◽  
pp. 138-143 ◽  
Author(s):  
Ronny A. Bell ◽  
John H. Summerson ◽  
John H. Summerson ◽  
Joseph C. Konen
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Psychosocial Factors ◽  
Body Fat ◽  
Fat Distribution
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