Human Midbrain Auditory Evoked Potentials Do Not Differ Between Bursts and Suppressions of Cortex Activity in Propofol Anesthesia: Case Report

Propofol, the most widely administered anesthetic agent, is used for sedation and general anesthesia. During general anesthesia it can induce bursts and suppressions of cortex activity, which exact mechanism of generation has not been identified yet. The aim of study was to investigate the difference between midbrain auditory evoked potentials recorded during bursts and suppressions of cortex activity. These potentials were registered from the drainage-electrode implanted in the cerebral aqueduct of an adult patient with an obstructive hydrocephalus who had undergone pineal region tumor removal through anterior interhemispheric transcallosal approach. The cortex activity was divided into rare bursts of alpha activity (total length of 9 seconds) and prolonged suppressions (total length of 104 seconds). Midbrain auditory evoked potentials included long latency peaks with no statistically significant difference in their amplitudes and latencies between bursts and suppressions of cortex activity. The results suggest that human midbrain auditory evoked potentials do not differ between bursts and suppressions of cortex activity in propofol anesthesia. Therefore, for clear midbrain auditory evoked potentials cognitive but not the total electrical activity of the cortex should be suppressed.

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Interhemispheric transcallosal intervenous approach to a pineal region tumor

Neurosurgical Focus: Video ◽

10.3171/2021.4.focvid2120 ◽

2021 ◽

Vol 5 (1) ◽

pp. V11

Author(s):

Daniel A. Donoho ◽

Guillermo Aldave

Keyword(s):

Extent Of Resection ◽

Pineal Region ◽

Cerebral Veins ◽

Surgical Morbidity ◽

Pineal Tumors ◽

Pineal Region Tumor ◽

Pineal Region Tumors ◽

Transcallosal Approach ◽

Formidable Challenge ◽

The Right

Pineal region tumors represent a formidable challenge to the neurosurgeon. Choosing the right approach is key to optimizing the extent of resection and minimizing surgical morbidity. In this video, the authors show an interhemispheric transcallosal approach to a pineal region tumor in a 15-year-old boy. The advantage of this corridor over posterior approaches is that it provides a nice view of the tumor plane with the venous complex, especially while dissecting tumor from the anterior aspect of the internal cerebral veins on their vertical path. Thus, this approach represents a safe and effective alternative for selected pineal tumors. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2120.

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Multimodal evoked potentials and the ovarian cycle in young ovulating women

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2000000300004 ◽

2000 ◽

Vol 58 (2B) ◽

pp. 418-423 ◽

Cited By ~ 8

Author(s):

LUIZ ANTONIO DE LIMA RESENDE ◽

MARIA DORVALINA SILVA ◽

FABÍOLA IMPEMBA ◽

NÍDIA BORGES ACHÔA ◽

ARTHUR OSCAR SCHELP

Keyword(s):

Statistical Analysis ◽

Menstrual Cycle ◽

Evoked Potentials ◽

Visual Evoked Potentials ◽

Auditory Evoked Potentials ◽

Brainstem Auditory Evoked Potentials ◽

Significant Difference ◽

Multimodal Evoked Potentials ◽

Cerebral Physiology ◽

Neurophysiological Basis

There is controversy over how hormonal conditions influence cerebral physiology. We studied pattern-shift visual evoked potentials (PS-VEP), brain stem auditory evoked potentials (BAEP) and short-latency somatosensory evoked potentials (SSEV) in 20 female volunteers at different phases of the menstrual cycle (estrogen phase, ovulatory day and progesterone phase). Statistical analysis showed decreased latencies for P100 (PS-VEP), N19 and P22 (SSEV) waves in the progesterone phase compared with the estrogen phase. There was no significant difference between the estrogen and the ovulation day values. Comparing the three above stages, there were no significant differences in the brainstem auditory evoked potentials. The reduction of the latencies of the potentials generated in multisynaptic circuits provides the first consistent neurophysiological basis for a tentative comprehension of human pre-menstrual syndrome.

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Auditory-evoked potentials in general anesthesia monitoring: baseline study of availability in relation to hearing function in awake status

Acta Anaesthesiologica Scandinavica ◽

10.1111/j.1399-6576.2005.00719.x ◽

2005 ◽

Vol 49 (6) ◽

pp. 774-777 ◽

Cited By ~ 1

Author(s):

L. De Siena ◽

F. Pallavicino ◽

M. Lacilla ◽

A. Canale ◽

A. Longobardo ◽

...

Keyword(s):

Evoked Potentials ◽

General Anesthesia ◽

Auditory Evoked Potentials ◽

Baseline Study ◽

Hearing Function ◽

Anesthesia Monitoring

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Electrical neuroimaging during auditory motion aftereffects reveals that auditory motion processing is motion sensitive but not direction selective

Journal of Neurophysiology ◽

10.1152/jn.00625.2012 ◽

2013 ◽

Vol 109 (2) ◽

pp. 321-331 ◽

Cited By ~ 9

Author(s):

David A. Magezi ◽

Karin A. Buetler ◽

Leila Chouiter ◽

Jean-Marie Annoni ◽

Lucas Spierer

Keyword(s):

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Right Hemisphere ◽

Prolonged Exposure ◽

Motion Processing ◽

Auditory Motion ◽

Global Field Power ◽

Significant Difference ◽

Electrical Neuroimaging ◽

Motion Detectors

Following prolonged exposure to adaptor sounds moving in a single direction, participants may perceive stationary-probe sounds as moving in the opposite direction [direction-selective auditory motion aftereffect (aMAE)] and be less sensitive to motion of any probe sounds that are actually moving (motion-sensitive aMAE). The neural mechanisms of aMAEs, and notably whether they are due to adaptation of direction-selective motion detectors, as found in vision, is presently unknown and would provide critical insight into auditory motion processing. We measured human behavioral responses and auditory evoked potentials to probe sounds following four types of moving-adaptor sounds: leftward and rightward unidirectional, bidirectional, and stationary. Behavioral data replicated both direction-selective and motion-sensitive aMAEs. Electrical neuroimaging analyses of auditory evoked potentials to stationary probes revealed no significant difference in either global field power (GFP) or scalp topography between leftward and rightward conditions, suggesting that aMAEs are not based on adaptation of direction-selective motion detectors. By contrast, the bidirectional and stationary conditions differed significantly in the stationary-probe GFP at 200 ms poststimulus onset without concomitant topographic modulation, indicative of a difference in the response strength between statistically indistinguishable intracranial generators. The magnitude of this GFP difference was positively correlated with the magnitude of the motion-sensitive aMAE, supporting the functional relevance of the neurophysiological measures. Electrical source estimations revealed that the GFP difference followed from a modulation of activity in predominantly right hemisphere frontal-temporal-parietal brain regions previously implicated in auditory motion processing. Our collective results suggest that auditory motion processing relies on motion-sensitive, but, in contrast to vision, non-direction-selective mechanisms.

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Analysis of the Effect of Musical Stimulation on Cortical Auditory Evoked Potentials

International Archives of Otorhinolaryngology ◽

10.1055/s-0038-1651507 ◽

2018 ◽

Vol 23 (01) ◽

pp. 031-035

Author(s):

Daiane Lima ◽

Simone Regaçone ◽

Anna Oliveira ◽

Yara Alcântara ◽

Eduardo Chagas ◽

...

Keyword(s):

Evoked Potentials ◽

Auditory System ◽

Repeated Measures ◽

Auditory Evoked Potentials ◽

P Value ◽

Mixed Analysis ◽

Sphericity Test ◽

Significant Difference ◽

Healthy Female ◽

Cortical Auditory Evoked Potentials

Introduction Cortical auditory evoked potentials (CAEPs) are bioelectric responses that occur from acoustic stimulations, and they assess the functionality of the central auditory system. Objective The objective of the present study was to analyze the effect of musical stimulation on CAEPs. Methods The sample consisted of 42 healthy female subjects, aged between 18 and 24 years, divided into two groups – G1: without musical stimulation prior to the CAEP examination; and G2: with stimulation prior to the examination. In both groups, as a pre-collection procedure, the complete basic audiological evaluation was performed. For the musical stimulation performed in G2, we used an MP4 player programmed to play Pachelbel's “Canon in D Major” for five minutes prior to the CAEP examination. To analyze the effect on the groups, the ear side and the ide–group interaction , a mixed analysis of variance (ANOVA) of repeated measures was performed. Box M test and Mauchly sphericity test were also performed. Results Test differences were considered statistically significant when the p-value was < 0.05 (5%). Thus, it was possible to observe that there was a statistically significant difference of the P2 component characterized by the decrease in the amplitude of response in the left ear in G2 when comparing the responses of CAEP with and without prior musical stimulation. Conclusion The result of the present study enabled us to conclude that there was a change in the response of CAEPs with musical stimulation.

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Neuroendoscopy in pineal region tumor with obstructive hydrocephalus

Annals of the College of Surgeons Hong Kong ◽

10.1046/j.1442-2034.2000.00072.x ◽

2000 ◽

Vol 4 (4) ◽

pp. 154-158 ◽

Cited By ~ 2

Author(s):

Danny Tat-Ming Chan ( ) ◽

Joseph Ming-Kuen Lam ( ) ◽

Wai-Sang Poon ( )

Keyword(s):

Obstructive Hydrocephalus ◽

Pineal Region ◽

Pineal Region Tumor

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Retractorless interforniceal approach for microsurgical resection of a papillary tumor of the pineal region: operative video and technical nuances

Neurosurgical Focus: Video ◽

10.3171/2021.4.focvid2139 ◽

2021 ◽

Vol 5 (1) ◽

pp. V12

Author(s):

James K. Liu ◽

Neil Majmundar

Keyword(s):

Obstructive Hydrocephalus ◽

Third Ventricle ◽

Lateral Position ◽

Pineal Region ◽

Gross Total Resection ◽

Cerebral Aqueduct ◽

Papillary Tumor ◽

Total Resection ◽

Microsurgical Resection ◽

Neurologically Intact

In this illustrative video, the authors demonstrate microsurgical resection of a papillary tumor of the pineal region using a retractorless interforniceal approach via the anterior interhemispheric transcallosal route. The tumor presented to the posterior third ventricle occluding the cerebral aqueduct, resulting in obstructive hydrocephalus. The retractorless interforniceal approach is performed in the lateral position with BICOL collagen spacers to keep the corridor open. Gross-total resection was achieved, and the patient was neurologically intact without needing a permanent shunt. The operative nuances and pearls of technique for safe microdissection and gentle handling of the retractorless interforniceal approach are demonstrated. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2139.

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Long latency auditory evokedpotentials in malnourished children

CoDAS ◽

10.1590/s2317-1782201300050000 ◽

2013 ◽

Vol 25 (5) ◽

pp. 407-412 ◽

Cited By ~ 7

Author(s):

Renata Parente de Almeida ◽

Carla Gentile Matas

Keyword(s):

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Impedance Measurement ◽

Pure Tone Audiometry ◽

Control Group ◽

Study Group ◽

Malnourished Children ◽

Long Latency ◽

Significant Difference ◽

The Right

PURPOSE: To characterize the findings obtained in the long latency auditory evoked potentials in malnourished children, as well as to compare them to the results obtained for children at the same age who present typical development. METHODS: Sixty-five children aged between 7 and 12 years old, of both genders, were evaluated. The control group consisted of 34 children with normal development and the study group consisted of 31 children diagnosed with malnutrition. All children underwent conventional pure tone audiometry, acoustic impedance measurement, dichotic digit test and long latency auditory evoked potentials. RESULTS: The study group presented a statistically significant difference for latencies of the components P1, N1 and P300. The latencies of these components were higher than those of the control group. Concerning the types of alterations found in the study group, increased latency for P1 and P300 and the absence of response in N1 were predominant. The control group showed a statistically significant difference in the amplitude of P300 when compared to the right and left ears. CONCLUSION: Malnourished children present with changes in the long latency auditory evoked potentials, suggesting a deficit in central auditory pathways and alterations in the processing of acoustic information.

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