scholarly journals A Study to Determine Maternal and Fetal Outcome in High Risk Pregnancies

Author(s):  
Dr. Meenal Patvekar et al., Dr. Meenal Patvekar et al., ◽  
Keyword(s):  
Author(s):  
J. Altmann ◽  
J. Kummer ◽  
F. Herse ◽  
L. Hellmeyer ◽  
D. Schlembach ◽  
...  

Abstract Background In Germany, performing fertility procedures involving oocyte donation is illegal, as stated by the Embryo Protection Law. Nonetheless, in our clinical routine we attend to a steadily rising number of pregnant women, who have sought oocyte donation abroad. Due to the legal circumstances many women opt to keep the origin of their pregnancy a secret. However, studies have shown, that oocyte donation is an independent risk factor for the development of pregnancy complications, such as preeclampsia. Objective The aim of this study is to evaluate maternal and neonatal outcomes of oocyte donation pregnancies in three large obstetric care units in Berlin, Germany. Methods We retrospectively analyzed all available medical data on oocyte donation pregnancies at Charité University hospital, Vivantes Hospital Friedrichshain, and Neukoelln in the German capital. Results We included 115 oocyte donation (OD) pregnancies in the present study. Our data are based on 62 singleton, 44 twin, 7 triplet, and 2 quadruplet oocyte donation pregnancies. According to our data, oocyte donation pregnancies are associated with a high risk of adverse maternal and fetal outcome, i.e., hypertension in pregnancy, preterm delivery, Cesarean section as mode of delivery, and increased peripartum hemorrhage. Conclusion Although oocyte donation is prohibited by German law, many couples go abroad to seek reproductive measures using oocyte donation after former treatment options have failed. OD pregnancies are associated with a high risk of preeclampsia, C-section as mode of delivery, and peripartum hemorrhage. Detailed knowledge of the associated risks is of utmost importance to both the patient and the treating physician and midwife.


Author(s):  
Seeta Sunil Garag ◽  
Vinay Raju D.

Background: Development of two fetus inside the uterus is called twin gestation. Twin gestation is considered as high-risk pregnancy due to associated high maternal morbidity and perinatal mortality in comparison with singleton pregnancies. The past two decades have witnessed a sharp rise in the incidence of twin and higher order gestations.Methods: Prospective analytical study of all women admitted in Obstetrics and Gynaecology department with twin pregnancy at KIMS Hubli, over a period of one year between November 2016 and October 2017.Results: There were 11,127 deliveries occurred in study period of one year, out of which there were 174 twin deliveries accounting for 1.56% of prevalence rate. Anemia was the commonest complication occurring in 160 cases contributing around 90%. Preterm delivery was the second complication occurring in 124 cases accounting for 71%. Among 348 babies, there were 40 perinatal death accounting 11%. There was no maternal death.Conclusions: Twin pregnancy is a high-risk condition, should have mandatory hospital delivery. Early detection, proper treatment improves both maternal and neonatal outcome.


2006 ◽  
Vol 9 (3) ◽  
pp. 234-238 ◽  
Author(s):  
Martin A. Weber ◽  
Peter G.J. Nikkels ◽  
Karen Hamoen ◽  
Johannes J. Duvekot ◽  
Ronald r. de Krijger

Chronic intervillositis (CI) and massive perivillous fibrin deposition (MFD), together with its related entity, maternal floor infarction (MFI), are rare and poorly understood placental lesions. Both MFD/MFI and CI are associated with poor fetal outcome and high risk of recurrence. We report a patient who was found to have both MFD and CI in the same placenta, resulting in severe intrauterine fetal growth restriction and intrauterine fetal death at 37 weeks of gestation. Characteristic histological findings included both very extensive perivillous deposition of fibrinoid material and a heavy infiltrate of CD68-positive macrophages/monocytes in the maternal intervillous space. To our knowledge, this is the first time the co-occurrence of MFD and CI is reported in the literature.


1977 ◽  
Vol 127 (1) ◽  
pp. 50-55 ◽  
Author(s):  
Sze-Ya Yeh ◽  
Alan Forsythe ◽  
Richard I. Lowensohn ◽  
Edward H. Hon

Author(s):  
V. .. Reznic

Preeclampsia-eclampsia is still one oi the leading causes of maternal and fetal morbidity and mortality. Despite active research for many years, the etiology of this disorder exclusive to human pregnancy is enigma. Recent evidence suggests there may be several underlying causes or predispositions leading to the signs of hypertension, proteinuria and edema, findings that allow us to make ithe diagnosis of the «syndrome» of preeclampsia. Despite improved prenatal care, severe preeclampsia and eclampsia still occur. Although understanding of the pal pathophysiology of there disordes has improved, treatment has not changed significantly in over 30 years. Although postponement of delivery in selected women with severe preeclampsia improves fetal outcome to a degree, this is not done without risk to the mot her. The search for the underlying cause of this disorder and for a clinical marker to predict those women who will develop preeclampsia-eclampsia is ongoing, with its prevention the ultimate goal. Moreover, prospective longitudinal studies are needed to better assess the role of circulating angiogenic factors for the identification women at high risk of preeclampsia and the early diagnosis of disease.


2020 ◽  
Vol 7 (3) ◽  
pp. 364-368
Author(s):  
V Mallikarjuna Reddy ◽  
◽  
Pavitra Reddy Nalamaru ◽  

Author(s):  
Aarthi Rajendran ◽  
Rajni Parikh

Background: Postdated pregnancy is gestation longer than 40 weeks or 280 day. Prolonged pregnancy is defined as any pregnancy that last 294 days or more. Reported frequency of post term pregnancy range from 3 - 1 4 percent with an average of about 10 percent. Several studies have concluded that these pregnancies are accompanied by a rise in perinatal morbidity and mortality. The presumed etiology for this rise is placental insufficiency. Abnormalities such as congenital anomalies, oligohydramnios, meconium aspiration, fetal asphyxia, fetal dysmaturity, macrosomia and shoulder dystocia are commonly observed in these pregnancies Materials and Methods: This study was conducted in the Department of Obstetrics and Gynecology, after approval from the Ethics Committee, from January 2019 to September2020 on 150 patients in the department of Obstetrics and Gynaecology, willing to participate and fulfilling the inclusion and excliusion criteria in the study period. Results: Of the total 150 women, 122 (81.34%) were in 40 weeks group; 28 (18.66%) in 41 weeks group and 0 (0%) were in > 42 weeks group. Most women (89.3%) were between 20-35 years of age. Among 150 women, 40 (26.6%) went into spontaneous labor, 87(8.0%) were induced andn23 (15.34%) was taken for caesarian section. Misoprostol, Dinoprostone gel and oxytocin were the different modes of induction (Table 7). Misoprostol was used in the majority of inductions followed by Dinoprostone gel. The success rate between these two is almost similar (92.45% & 95.1%).Lscs rate was 15.33%.Most of the newborn had weight between 2.5-3.5kg in 68.25% of women in gestational age >40 weeks. Conclusions: The present study, we conclude that postdated pregnancy can be considered as a high risk factor from the point of fetal outcome as there is more fetal morbidity. Keywords: High risk pregnancies, maternal mortality, Outcomes, Perinatal mortality, postdated pregnancy.


2020 ◽  
pp. 1-3
Author(s):  
Karishma Gandhi ◽  
Ishit Shah ◽  
Ram Kumar Patidar

Background: High risk pregnancy needs special antepartum as well as intrapartum care and investigations. CTG is aadmissionscreening test to monitor fetal wellbeing by use of cardiotocograph. It monitors fetal heart rate and uterine contractions. Color Doppler is ultrasound dependent test which uses vascular flow velocities and Doppler waveform to predict fetal outcome. Objective: Comparison of efficiency of CTG & Color Doppler ultrasound for intrapartum fetal surveillance in high risk pregnancy. Methods: Retrospective study of 100 high risk pregnancies of ≥ 34 weeks POG in labor with CTG and color Doppler findings were done on admission at Gujarat Adani Institute of Medical Sciences, Bhuj. Subjects were classified into 4 groups based on CTG and color Doppler findings. Maternal and fetal outcome were recorded and correlated with CTGand color Dopplerfindings. Results: Most common cause of high-risk pregnancy was preeclampsia(n=60/100,60%).In our study, rate of normal delivery was 40% and c-section was 60% (31% elective & 29% emergency). Out of 100 fetuses, 76 were healthy, 22 were admitted in NICU (6 NICU deaths) and 2 were still birth. Perinatal outcome was most favorable with normal CTG and Color doppler and was least favorable with both of them abnormal. Outcome was intermittent in other two groups. CTG found to have sensitivity 62.5% and specificity 82.5% in detection of adverse fetal outcome. Similarly,sensitivity and specificity of color doppler was 48.8% and 98.6% respectively. Conclusions: In our study it was found that CTG is more sensitive and color Doppler is more specific in detection of adverse fetal outcome.


2018 ◽  
Vol 12 (1) ◽  
pp. 50-54
Author(s):  
Jwala Thapa ◽  
Rajib Sah

Aims: The objective of the study was to evaluate the relationship between admission cardiotocography and fetal outcome among high risk obstetrics patients.Methods: The study was a hospital based observational study of 130 patients, conducted at Paropakar maternity and Women’s Hospital, Kathmandu from January 2014 to June 2014. A 20-minute cardiotocography reading was done in admission room and reading was categorized in 3 groups- reactive, equivocal and ominous. The results were compared to see the relationship between normal and abnormal admission test in terms of color of liquor, mode of delivery, Apgar score at 5 minutes, neonatal resuscitation needed and NICU admission.Results: Result of admission test (AT) was reactive in 95(73.1%), equivocal in 19(14.6%) and ominous in 16(12.3%) which has significant relationship with mode of delivery (p-value=0.003), color of liquor (p-value=0.000), Apgar score at 5 minutes (p-value=0.000) and perinatal outcome (p-value=0.00). Incidences of vaginal deliveries were more common when the test was reactive whereas operative deliveries were more common when the AT was ominous/equivocal.Conclusions: Admission test is simple, cost effective and non-invasive technique for detecting fetal hypoxia and predicting fetal outcome that can serve as a screening tool in triaging fetuses of high-risk patients in developing countries with a heavy workload and limited resources.


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