Guidelines for the diagnosis and treatment of acute pulmonary embolism

2020 ◽  
Vol 13 (1) ◽  
pp. 116-119
Author(s):  
Anna Sobieszek ◽  
Ewelina Zamecka ◽  
Paulina Ładak ◽  
Aneta Mrozińska ◽  
Marek Kuch
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Diagnosis And Treatment

scholarly journals The Diagnosis and Treatment of Acute Pulmonary Embolism

2010 ◽  
Author(s):  
Alexander Schellhaaß ◽  
Andreas Walther ◽  
Stavros Konstantinides ◽  
Bernd W. Böttiger
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Diagnosis And Treatment

Clinical and hemodynamic spectrum, diagnosis, and treatment of acute pulmonary embolism: The aggressive approach

2011 ◽  
Vol 3 (01) ◽  
pp. 41-54
Author(s):  
Ole Lund ◽  
Torsten Nielsen ◽  
Morten Hedegaard ◽  
Hans Hansen ◽  
Ole Albrechtsen
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Diagnosis And Treatment ◽  
Aggressive Approach

scholarly journals Diagnosis and treatment of acute pulmonary embolism

Cor et Vasa ◽  
2013 ◽  
Vol 55 (6) ◽  
pp. e497-e509 ◽  
Author(s):  
Jiří Widimský
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Diagnosis And Treatment

scholarly journals Acute pulmonary embolism—its diagnosis and treatment from a multidisciplinary viewpoint

2021 ◽  
Author(s):  
Hannah C. Kulka ◽  
Andreas Zeller ◽  
Jürgen Fornaro ◽  
Walter A. Wuillemin ◽  
Stavros Konstantinides ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Diagnosis And Treatment

Tissue plasminogen activator as a novel diagnostic aid in acute pulmonary embolism

VASA ◽  
2014 ◽  
Vol 43 (6) ◽  
pp. 450-458 ◽  
Author(s):  
Julio Flores ◽  
Ángel García-Avello ◽  
Esther Alonso ◽  
Antonio Ruíz ◽  
Olga Navarrete ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Negative Predictive Value ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Predictive Value ◽  
Acute Pulmonary Embolism ◽  
Enzyme Linked Immunosorbent Assay ◽  
Diagnostic Utility ◽  
Tissue Plasminogen ◽  
D Dimer

Background: We evaluated the diagnostic efficacy of tissue plasminogen activator (tPA), using an enzyme-linked immunosorbent assay (ELISA) and compared it with an ELISA D-dimer (VIDAS D-dimer) in acute pulmonary embolism (PE). Patients and methods: We studied 127 consecutive outpatients with clinically suspected PE. The diagnosis of PE was based on a clinical probability pretest for PE and a strict protocol of imaging studies. A plasma sample to measure the levels of tPA and D-dimer was obtained at enrollment. Diagnostic accuracy for tPA and D-dimer was determined by the area under the receiver operating characteristic (ROC) curve. Sensitivity, specificity, predictive values, and the diagnostic utility of tPA with a cutoff of 8.5 ng/mL and D-dimer with a cutoff of 500 ng/mL, were calculated for PE diagnosis. Results: PE was confirmed in 41 patients (32 %). Areas under ROC curves were 0.86 for D-dimer and 0.71 for tPA. The sensitivity/negative predictive value for D-dimer using a cutoff of 500 ng/mL, and tPA using a cutoff of 8.5 ng/mL, were 95 % (95 % CI, 88–100 %)/95 % (95 % CI, 88–100 %) and 95 % (95 % CI, 88–100 %)/94 %), respectively. The diagnostic utility to exclude PE was 28.3 % (95 % CI, 21–37 %) for D-dimer and 24.4 % (95 % CI, 17–33 %) for tPA. Conclusions: The tPA with a cutoff of 8.5 ng/mL has a high sensitivity and negative predictive value for exclusion of PE, similar to those observed for the VIDAS D-dimer with a cutoff of 500 ng/mL, although the diagnostic utility was slightly higher for the D-dimer.

Pulmonary emboli due to venous aneurysm of extremities

VASA ◽  
2011 ◽  
Vol 40 (4) ◽  
pp. 327-332 ◽  
Author(s):  
Gabrielli ◽  
Rosati ◽  
Vitale ◽  
Millarelli ◽  
Siani ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Surgical Resection ◽  
Potential Risk ◽  
Acute Pulmonary Embolism ◽  
Prophylactic Surgery ◽  
Venous Aneurysm ◽  
Pulmonary Emboli ◽  
Thromboembolic Events ◽  
Thromboembolic Complications ◽  
Risk Patients

Venous aneurysms are uncommon but they can have devastating consequences, including pulmonary embolism, other thromboembolic events and death. We report six cases of venous aneurysm of the extremities, in which the first sign of presence was acute pulmonary embolism. Surgical resection is recommended whenever possible. Our experience suggests that prophylactic surgery is cautiously recommended for low-risk patients with venous aneurysms of the abdomen and strongly recommended for extremity deep and superficial venous aneurysms for their potential risk of developing thromboembolic complications despite adequate anticoagulation. Other venous aneurysms should be excised only if they are symptomatic or enlarging.

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