Knowledge gaps impacting the development of bovine viral diarrhea virus control programs in the United States

2009 ◽  
Vol 235 (10) ◽  
pp. 1171-1179 ◽  
Author(s):  
Julia F. Ridpath ◽  
Robert W. Fulton
Virology ◽  
2019 ◽  
Vol 535 ◽  
pp. 279-282 ◽  
Author(s):  
John D. Neill ◽  
Beate M. Crossley ◽  
Ana C. Mosena ◽  
Julia F. Ridpath ◽  
Darrell O. Bayles ◽  
...  

2009 ◽  
Vol 234 (4) ◽  
pp. 519-529 ◽  
Author(s):  
Christina L. Topliff ◽  
David R. Smith ◽  
Sharon L. Clowser ◽  
David J. Steffen ◽  
Jamie N. Henningson ◽  
...  

2017 ◽  
Vol 29 (3) ◽  
pp. 362-365 ◽  
Author(s):  
Ninnet Gómez-Romero ◽  
Francisco J. Basurto-Alcántara ◽  
Antonio Verdugo-Rodríguez ◽  
Fernando V. Bauermann ◽  
Julia F. Ridpath

Bovine viral diarrhea virus (BVDV) infects cattle populations worldwide, causing significant economic losses though its impact on animal health. Previous studies have reported the prevalence of BVDV species and subgenotypes in cattle from the United States and Canada. We investigated the genetic diversity of BVDV strains detected in bovine serum samples from 6 different Mexican regions. Sixty-two BVDV isolates from Mexico were genetically typed based on comparison of sequences from the 5′ untranslated region (5′-UTR) of the viral genome. Phylogenetic reconstruction indicated that 60 of the samples belonged to the BVDV-1 genotype and 2 to the BVDV-2 genotype. Comparison of partial 5′-UTR sequences clustered 49 samples within BVDV-1c, 8 samples within BVDV-1a, 3 samples within BVDV-1b, and 2 samples clustered with the BVDV-2a subgenotypes. Our study, combined with information previously published on BVDV field strain diversity in the United States and Canada, benefits the development of effective detection assays, vaccines, and control programs for North America.


2017 ◽  
Vol 15 (2) ◽  
pp. e05R01 ◽  
Author(s):  
Francisco J. Diéguez ◽  
Manuel Cerviño ◽  
Eduardo Yus

Bovine viral diarrhea virus (BVDV), a member of the genus Pestivirus of the family Flaviviridae, causes significant losses in cattle farming worldwide because of reduced milk production, increased mortality of young animals and reproductive, respiratory and intestinal problems. The virus is characterized by an important genetic, and consequently antigenic and pathogenic diversity. Knowing the variability of viral strains present in a population provides valuable information, particularly relevant for control programs development, vaccination recommendations and even identification of likely infection sources. Such information is therefore important at both local and regional levels. This review focuses on the genetic diversity of BVDV isolates infecting cattle in Spain over the last years. According to the published data, the most prevalent BVDV group in Spain was 1b, and to a lesser extent 1d, 1e and 1f. Besides, BVDV-2 has also been found in Spain with several ratified isolates. The studies carried out in Spain also showed increased genetic heterogeneity of BVDV strains, possibly due to a more intensive use of analytical tools available, presenting studies with increasingly greater sample sizes.


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