Discrepancies between Premorbid and Current IQ as a Function of Progressive Mental Deterioration

2005 ◽  
Vol 100 (1) ◽  
pp. 69-76 ◽  
Author(s):  
Francis McCarthy ◽  
William J. Burns ◽  
Alfred H. Sellers
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Reading Tests ◽  
Adult Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Wide Range Achievement Test ◽  
Wide Range ◽  
Adult Reading ◽  
Severity Of The Disease ◽  
Wechsler Adult Intelligence

The declining cognitive functioning typically found in patients with Alzheimer's disease presents an opportunity to study that decline. The changing magnitude of ever widening discrepancies between premorbid estimators of IQ and observed IQ increases as severity of the disease increases. Premorbid IQs estimated by these scores (the National Adult Reading Test–Revised, the reading tests of the Revised and Third Editions of the Wide Range Achievement Test, and a demographically based regression index for the Wechsler Adult Intelligence Scale–Revised) had relatively similar discrepancies from obtained WAIS–R Full Scale IQs in samples of normal elderly ( n = 30), and elderly patients diagnosed with mild ( n = 30) and moderate Alzheimer's disease ( n = 30) dementia. The discrepancies became larger, regardless of premorbid estimator, as disease severity progressed from none to mild to moderate across the samples.

scholarly journals A-011 Stability of Impairment Rating Discrepancies in a Longitudinal Observational Alzheimer’s Study

2020 ◽  
Vol 35 (6) ◽  
pp. 801-801
Author(s):  
Kaylegian J ◽  
Ritter A ◽  
Caldwell J
Keyword(s):  
Rating Scale ◽  
Digit Span ◽  
Neuropsychological Test ◽  
Verbal Learning ◽  
Clinical Dementia Rating ◽  
Adult Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Wide Range Achievement Test ◽  
Wide Range ◽  
Wechsler Adult Intelligence

Abstract Objective The present study investigated frequency and 12-month persistence of discrepant Clinical Dementia Rating (CDR) and comprehensive neuropsychological assessment ratings of impairment. Methods We examined CDR and neuropsychological test scores from year 1 and 2 visits of 162 adults enrolled in a longitudinal observational study. Neuropsychological measures included Wide Range Achievement Test, American National Adult Reading Test, Rey Auditory Verbal Learning Test, Brief Visuospatial Memory Test-Revised, Dementia Rating Scale 2nd edition, Boston Naming, Verbal Fluency/Color Word Interference from the Delis-Kaplan Executive Function System, Judgment of Line Orientation, Trail Making Test, Symbol Digit Modalities Test, and Digit Span/Letter Number Sequencing from The Wechsler Adult Intelligence Scale 4th edition. Discrepancies were defined as: CDR = 0 and 2 test impairments, CDR = 0.5 and > 5 or 0 impairments, CDR = 1 and 0 impairments. Results Including all test domains, 40.1% of participants in year 1 and 44.3% in year 2 showed discrepancies. 69% maintained this discrepancy at year 2 and 68% of these showed no change in discrepancy type. Considering only memory tests, 37% of participants in year 1 and 28.4% in year 2 showed discrepancies, with 45% maintaining at year 2 (74% showing no change in discrepancy type). A majority of discrepancies observed in both years 1 and 2 revealed the CDR was under reporting impairment compared to the neuropsychological battery year. Conclusions The results provide evidence that within our study population, impairment as rated by the CDR frequently does not match the level of measured cognitive impairment and this observation is stable year to year.

scholarly journals The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer’s disease

2009 ◽  
Vol 16 (1) ◽  
pp. 77-83 ◽  
Author(s):  
MELISSA LAMAR ◽  
DAVID J. LIBON ◽  
ANGELA V. ASHLEY ◽  
JAMES J. LAH ◽  
ALLAN I. LEVEY ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Error Analysis ◽  
Vascular Diseases ◽  
Zero Point ◽  
Adult Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Caregiver Education ◽  
Wechsler Adult Intelligence ◽  
The Impact

AbstractRecent evidence suggests that patients with Alzheimer’s disease (AD) and vascular comorbidities (VC) perform worse across measures of verbal reasoning and abstraction when compared to patients with AD alone. We performed a qualitative error analysis of Wechsler Adult Intelligence Scale-III Similarities zero-point responses in 45 AD patients with varying numbers of VC, including diabetes, hypertension, and hypercholesterolemia. Errors were scored in set if the answer was vaguely related to how the word pair was alike (e.g., dog-lion: “they can be trained”) and out of set if the response was unrelated (“a lion can eat a dog”). AD patients with 2–3 VC did not differ on Similarities total score or qualitative errors from AD patients with 0–1 VC. When analyzing the group as a whole, we found that increasing numbers of VC were significantly associated with increasing out of set errors and decreasing in set errors in AD. Of the vascular diseases investigated, it was only the severity of diastolic blood pressure that significantly correlated with out of set responses. Understanding the contribution of VC to patterns of impairment in AD may provide support for directed patient and caregiver education concerning the presentation of a more severe pattern of cognitive impairment in affected individuals. (JINS, 2010, 16, 77–83.)

Estimation of Premorbid Intelligence in Schizophrenia

1992 ◽  
Vol 161 (1) ◽  
pp. 69-74 ◽  
Author(s):  
J. R. Crawford ◽  
J. A. O. Besson ◽  
M. Bremner ◽  
K. P. Ebmeier ◽  
R. H. B. Cochrane ◽  
...  
Keyword(s):  
Alternative Explanation ◽  
Adult Intelligence Scale ◽  
Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Premorbid Intelligence ◽  
Schizophrenic Patients ◽  
Adult Reading ◽  
Valid Estimate ◽  
Wechsler Adult Intelligence ◽  
National Adult Reading Test

To determine whether the National Adult Reading Test (NART) would provide a valid estimate of premorbid intelligence in schizophrenia, two schizophrenic samples were recruited, one consisting of 35 patients resident in long-stay wards, the other of 29 patients normally resident in the community. Schizophrenic patients were individually matched for age, sex, and education with a healthy, normal subject. Both schizophrenic samples scored significantly lower on the Wechsler Adult Intelligence Scale (WAIS) than their respective control groups. NART-estimated IQ did not differ significantly between the community-resident schizophrenics and their controls, suggesting that the NART provides a valid means of estimating premorbid intelligence in such a population. NART-estimated IQ was significantly lower in the long-stay sample than in their controls. Although low NART scores in this latter sample could be a valid reflection of low premorbid IQ, the alternative explanation that NART performance was impaired by onset of the disease cannot be ruled out.

scholarly journals ACCURACY OF NEUROPSYCHOLOGICAL TESTS IN PATIENTS WITH BIOLOGICAL DIAGNOSIS OF ALZHEIMER’S DISEASE

2021 ◽  
Author(s):  
Patrícia Peles ◽  
Larissa Salvador ◽  
Luciano Mariano ◽  
Viviane Carvalho ◽  
Clarisse Frieldlaender ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychological Tests ◽  
Rating Scale ◽  
Digit Span ◽  
Verbal Learning ◽  
High Sensitivity ◽  
High Specificity ◽  
Adult Intelligence Scale ◽  
Wechsler Adult Intelligence Scale

Background: Neuropsychological tests are important tools for the diagnosis of mild cognitive impairment or dementia due to Alzheimer’s disease (AD). Objective: To investigate the accuracy of common neuropsychological tests used in the clinical setting for AD diagnosis. Methods: Forty two patients with diagnosis of AD continuum [A+T+/-(N)+/-] and 32 non-AD [A-T+/-(N)+/-]. All participants were submitted to a thorough neuropsychological assessment with the following instruments: Mattis Dementia Rating Scale (DRS), Rey’s Auditory Verbal Learning Test (RAVLT), Boston naming-Consortium to Establish a Registry for Alzheimer’s Disease, a reduced version of the CERAD, Digit Span Forward (DSF), Digit Span Backward (DSB) and Cubes from The Wechsler Adult Intelligence Scale (WAIS), verbal fluency – animals (VF-A), and FAS. Results: Memory (MEM) and Initiation/Perseveration (I/P) subscales of the DRS, FAS, Digit Span Backward (DSB) and Boston naming displayed good discrimination between AD and non-AD patients. The MEM subscale of the DRS, RAVLT A6 and FAS presented high sensitivity (90% or more) for AD diagnosis, while DSF displayed high specificity. Non-AD patients had greater difficulty in FAS, DSB and in Boston naming. Conclusion: Performance of patients with biological diagnosis of AD on MEM and I/P of DRS, and RAVLT A7 was significantly different from that of non-AD subjects.

Geschlechtseffekte bei Intelligenz- und Gedächtnisleistungen

2015 ◽  
Vol 26 (1) ◽  
pp. 5-16 ◽  
Author(s):  
Anja C. Lepach ◽  
Wiebke Reimers ◽  
Franz Pauls ◽  
Franz Petermann ◽  
Monika Daseking
Keyword(s):  
Adult Intelligence Scale ◽  
Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Adult Intelligence ◽  
Wechsler Memory Scale ◽  
Wechsler Adult Intelligence

Diese Studie untersucht die Zusammenhänge von Intelligenz- und Gedächtnisleistungen in der Wechsler Adult Intelligence Scale-IV und der Wechsler Memory Scale-IV unter Berücksichtigung des Geschlechts (N = 137 Gesunde, 63 w/74 m). Ein Vorteil der weiblichen Testpersonen im verbalen episodischen Gedächtnis sowie in einzelnen Aufgaben zur Verarbeitungsgeschwindigkeit konnte beobachtet werden. Die männlichen Testpersonen schnitten in den Untertests Allgemeines Wissen und Visuelle Puzzles besser ab. Wie gut Gedächtnisleistungen Intelligenzleistungen erklären beziehungsweise vorhersagen, ist aufgrund unserer Ergebnisse nicht nur abhängig von den Aufgaben, sondern auch vom Geschlecht.

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