Effects of Caffeine on the Trigeminal Blink Reflex

2005 ◽  
Vol 100 (2) ◽  
pp. 493-496 ◽  
Author(s):  
Edward J. Schicatano
Keyword(s):  
Trigeminal Nerve ◽  
Acoustic Startle ◽  
Startle Reflex ◽  
Blink Reflex ◽  
Psychomotor Effects ◽  
Brainstem Reflex ◽  
Decaffeinated Coffee ◽  
Reflex Blinks ◽  
Caffeinated Coffee ◽  
Stimulation Of

The acoustic startle and trigeminal blink reflexes share the same motor output. Since caffeine has been shown to augment the startle reflex, it was proposed that caffeine would also increase the trigeminal blink reflex. In 6 humans, the effects of caffeine (100 mg) on the trigeminal blink reflex were investigated. Reflex blinks were elicited by stimulation of the supraorbital branch of the trigeminal nerve. Following ingestion of caffeinated coffee, reflex blinks increased in amplitude and duration and occurred at a shorter latency than reflex blinks following ingestion of decaffeinated coffee. Since the blink reflex is a brainstem reflex, these results suggest that the psychomotor effects of caffeine facilitate brainstem processing.

Reliability of the nociceptive blink reflex evoked by electrical stimulation of the trigeminal nerve in humans

2017 ◽  
Vol 21 (8) ◽  
pp. 2453-2463 ◽  
Author(s):  
Yuri Martins Costa ◽  
Lene Baad-Hansen ◽  
Leonardo Rigoldi Bonjardim ◽  
Paulo César Rodrigues Conti ◽  
Peter Svensson
Keyword(s):  
Electrical Stimulation ◽  
Trigeminal Nerve ◽  
Blink Reflex ◽  
Nociceptive Blink Reflex ◽  
Stimulation Of

Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women

1995 ◽  
Vol 269 (4) ◽  
pp. E671-E678 ◽  
Author(s):  
D. Bracco ◽  
J. M. Ferrarra ◽  
M. J. Arnaud ◽  
E. Jequier ◽  
Y. Schutz
Keyword(s):  
Heart Rate ◽  
Energy Metabolism ◽  
Lipid Oxidation ◽  
Substrate Oxidation ◽  
The Other ◽  
Obese Women ◽  
Concomitant Increase ◽  
Decaffeinated Coffee ◽  
Caffeinated Coffee ◽  
Stimulation Of

The magnitude of coffee-induced thermogenesis and the influence of coffee ingestion on substrate oxidation were investigated in 10 lean and 10 obese women, over two 24-h periods in a respiratory chamber. On one occasion the subjects consumed caffeinated coffee and on the other occasion, decaffeinated coffee. The magnitude of thermogenesis was smaller in obese (4.9 +/- 2.0%) than in lean subjects (7.6 +/- 1.3%). The thermogeneic response to caffeine was prolonged during the night in lean women only. The coffee-induced stimulation of energy expenditure was mediated by a concomitant increase in lipid and carbohydrate oxidation. During the next day, in postabsorptive basal conditions, the thermogenic effect of coffee had vanished, but a significant increase in lipid oxidation was observed in both groups. The magnitude of this effect was, however, blunted in obese women (lipid oxidation increased by 29 and 10% in lean and obese women, respectively). Caffeine increased urinary epinephrine excretion. Whereas urinary caffeine excretion was similar in both groups, obese women excreted more theobromine, theophylline, and paraxanthine than lean women. Despite the high levels of urinary methylxanthine excretion, thermogenesis and lipid oxidation were less stimulated in obese than in lean subjects.

scholarly journals Diagnostic potential of acoustic startle reflex, acoustic blink reflex, and electro-oculography in progressive supranuclear palsy: A prospective study

2003 ◽  
Vol 18 (11) ◽  
pp. 1273-1279 ◽  
Author(s):  
Alexandre Gironell ◽  
Jaime Kulisevsky ◽  
Carles Roig ◽  
Berta Pascual-Sedano ◽  
Antoni Rodríguez-Fornells ◽  
...  
Keyword(s):  
Prospective Study ◽  
Progressive Supranuclear Palsy ◽  
Acoustic Startle ◽  
Startle Reflex ◽  
Blink Reflex ◽  
Acoustic Startle Reflex ◽  
Diagnostic Potential ◽  
A Prospective Study

Clinical and electrophysiological studies on sensory conduction mediated by the accessory rootlets of the human trigeminal nerve

1975 ◽  
Vol 42 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Adolfo Ley ◽  
Luis Montserrat ◽  
Fernando Bacci ◽  
Adolfo Ley
Keyword(s):  
Trigeminal Nerve ◽  
Blink Reflex ◽  
Content Type ◽  
Sensory Conduction ◽  
Before And After ◽  
Electrophysiological Studies ◽  
Sensory Fibers ◽  
Sensory Root ◽  
Fine Print ◽  
Stimulation Of

✓ The authors present records of potentials evoked in the roots of the trigeminal nerve by stimulation of its cutaneous branches. Records were made during nine operations for tic douloureux in which the main sensory root of the trigeminal nerve was totally sectioned under the microscope by the transcerebellar route. In every case, the accessory (aberrant) and motor roots were easily identified and spared. Records before and after total main sensory root division showed persistence of evoked potentials in the aberrant and motor fibers. Partial preservation of sensation and blink reflex in these cases reinforced the impression that there is somatic sensory conduction through true aberrant sensory fibers running between the motor and main sensory roots.

scholarly journals Occult Fifth Nerve Dysfunction In Multiple Sclerosis

1981 ◽  
Vol 8 (3) ◽  
pp. 221-225 ◽  
Author(s):  
Andrew Eisen ◽  
Donald Paty ◽  
Sherrill Purves ◽  
Maureen Hoirch
Keyword(s):  
Multiple Sclerosis ◽  
Trigeminal Nerve ◽  
Clinical Evidence ◽  
Normal Subjects ◽  
Blink Reflex ◽  
Clinical Findings ◽  
Trigeminal Nerve Stimulation ◽  
Stimulus Artefact ◽  
Nerve Dysfunction ◽  
Stimulation Of

SUMMARY:Somatosensory evoked potentials (SEPs) were recorded following trigeminal nerve stimulation in 25 normal subjects. Mucosal stimulation of the lip resulted in a reduced stimulus artefact. The three initial peaks, N13, P19, and N30, measured respectively 12.8 ± 0.9 S−3, 19.3 ± 1.4 S−3 and 28.6 ± 1.7 S−3. Blink reflex studies were also performed in most of these subjects. In 41.4% of 29 patients with established or suspected multiple sclerosis, the trigeminal SEP was abnormal. Additional use of the blink reflex raised the overall incidence of trigeminal nerve dysfunction to 51.7%. None of the patients had clinical evidence of fifth nerve involvement either historically or on examination. Four of seven patients with progressive spinal MS and two patients whose only deficit was that of optic neuritis, had abnormal trigeminal SEPs. It is concluded that occult involvement of the pontine fifth nerve structures occurs frequently in MS despite the rarity of corresponding clinical findings. The trigeminal SEP is a useful additional neurophysiological method.

Modulation of the acoustic startle reflex by emotionally-toned filmclips

1996 ◽  
Author(s):  
Hossein Kaviani ◽  
Jeffrey A. Gray ◽  
Stuart A. Checkley ◽  
Veena Kumari ◽  
Philip J. Corr ◽  
...  
Keyword(s):  
Acoustic Startle ◽  
Startle Reflex ◽  
Acoustic Startle Reflex

scholarly journals Effect of Aging, Gender and Sensory Stimulation of TRPV1 Receptors with Capsaicin on Spontaneous Swallowing Frequency in Patients with Oropharyngeal Dysphagia: A Proof-of-Concept Study

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 461
Author(s):  
Weslania Nascimento ◽  
Noemí Tomsen ◽  
Saray Acedo ◽  
Cristina Campos-Alcantara ◽  
Christopher Cabib ◽  
...  
Keyword(s):  
Oropharyngeal Dysphagia ◽  
Sensory Stimulation ◽  
Age And Gender ◽  
Post Stroke ◽  
Brainstem Reflex ◽  
Trpv1 Receptors ◽  
Volume Viscosity ◽  
And Gender ◽  
Effect Of Age ◽  
Stimulation Of

Spontaneous swallowing contributes to airway protection and depends on the activation of brainstem reflex circuits in the central pattern generator (CPG). We studied the effect of age and gender on spontaneous swallowing frequency (SSF) in healthy volunteers and assessed basal SSF and TRPV1 stimulation effect on SSF in patients with post-stroke oropharyngeal dysphagia (OD). The effect of age and gender on SSF was examined on 141 healthy adult volunteers (HV) divided into three groups: GI—18–39 yr, GII—40–59 yr, and GIII—>60 yr. OD was assessed by the Volume–Viscosity Swallowing Test (VVST). The effect of sensory stimulation with capsaicin 10−5 M (TRPV1 agonist) was evaluated in 17 patients with post-stroke OD, using the SSF. SSF was recorded in all participants during 10 min using surface electromyography (sEMG) of the suprahyoid muscles and an omnidirectional accelerometer placed over the cricothyroid cartilage. SSF was significantly reduced in GII (0.73 ± 0.50 swallows/min; p = 0.0385) and GIII (0.50 ± 0.31 swallows/min; p < 0.0001) compared to GI (1.03 ± 0.62 swallows/min), and there was a moderate significant correlation between age and SFF (r = −0.3810; p < 0.0001). No effect of gender on SSF was observed. Capsaicin caused a strong and significant increase in SSF after the TRPV1 stimulation when comparing to basal condition (pre-capsaicin: 0.41 ± 0.32 swallows/min vs post-capsaicin: 0.81 ± 0.51 swallow/min; p = 0.0003). OD in patients with post-stroke OD and acute stimulation with TRPV1 agonists caused a significant increase in SSF, further suggesting the potential role of pharmacological stimulation of sensory pathways as a therapeutic strategy for CPG activation in patients with OD.

TRIGEMINAL PROJECTIONS IN THE RETICULAR FORMATION OF THE PONS IN THE CAT

1962 ◽  
Vol 40 (1) ◽  
pp. 7-12
Author(s):  
J. M. Langlois ◽  
Guy Lamarche
Keyword(s):  
Reticular Formation ◽  
Trigeminal Nerve ◽  
Unit Activity ◽  
Functional Organization ◽  
Pontine Reticular Formation ◽  
Recording Unit ◽  
Spatial Convergence ◽  
The Face ◽  
High Degree ◽  
Stimulation Of

The projections of the trigeminal nerve in the pontine reticular formation of the cat have been investigated by recording unit activity, after physiological stimulation of the face, in 30 "encéphales isolés" preparations. No somatotopical arrangement was found but a high degree of spatial convergence onto pontine reticular units exists and a certain degree of functional organization was observed.

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