scholarly journals The Correspondence between Fluid Balance and Body Weight Change Measurements in Critically Ill Adult Patients

2021 ◽  
Vol 7 (1) ◽  
pp. 46-53
Author(s):  
Ana Carolina Peçanha Antonio ◽  
Vivian Rodrigues Fernandes ◽  
Karina de Oliveira Azzolin
Keyword(s):  
Body Weight ◽  
Fluid Balance ◽  
Weight Change ◽  
Total Body Weight ◽  
Body Weight Change ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Fluid Status ◽  
Total Body ◽  
Cumulative Fluid Balance

Abstract Introduction Positive fluid status has been associated with a worse prognosis in intensive care unit (ICU) patients. Given the potential for errors in the calculation of fluid balance totals and the problem of accounting for indiscernible fluid losses, measurement of body weight change is an alternative non-invasive method commonly used for estimating body fluid status. The objective of the study is to compare the measurements of fluid balance and body weight changes over time and to assess their association with ICU mortality. Methods This prospective observational study was conducted in the 34-bed multidisciplinary ICU of a tertiary teaching hospital in southern Brazil. Adult patients were eligible if their expected length of stay was more than 48 hours, and if they were not receiving an oral diet. Clinical demographic data, daily and cumulative fluid balance with and without indiscernible water loss, and daily and total body weight changes were recorded. Agreement between daily fluid balance and body weight change, and between cumulative fluid balance and total body weight change were calculated. Results Cumulative fluid balance and total body weight change differed significantly among survivors and non survivors respectively, +2.53L versus +5.6L (p= 0.012) and -3.05kg vs -1.1kg (p= 0.008). The average daily difference between measured fluid balance and body weight was +0.864 L/kg with a wide interval: -3.156 to +4.885 L/kg, which remained so even after adjustment for indiscernible losses (mean bias: +0.288; limits of agreement between -3.876 and +4.452 L/kg). Areas under ROC curve for cumulative fluid balance, cumulative fluid balance with indiscernible losses and total body weight change were, respectively, 0.65, 0.56 and 0.65 (p= 0.14). Conclusion The results indicated the absence of correspondence between fluid balance and body weight change, with a more significant discrepancy between cumulative fluid balance and total body weight change. Both fluid balance and body weight changes were significantly different among survivors and non-survivors, but neither measurement discriminated ICU mortality.

Association of Body Weight Change and Fluid Balance With Extubation Failure in Intensive Care Unit Patients: A Single-Center Observational Study

2019 ◽  
Vol 36 (2) ◽  
pp. 175-181
Author(s):  
Shota Maezawa ◽  
Daisuke Kudo ◽  
Noriko Miyagawa ◽  
Satoshi Yamanouchi ◽  
Shigeki Kushimoto
Keyword(s):  
Logistic Regression ◽  
Body Weight ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Fluid Balance ◽  
Weight Change ◽  
Invasive Mechanical Ventilation ◽  
Extubation Failure ◽  
Body Weight Change ◽  
Failure Group

Purpose: To elucidate whether fluid balance and body weight change are associated with failed planned extubation. Materials and Methods: Patients who received invasive mechanical ventilation for over 24 hours were enrolled and divided into extubation success and extubation failure groups. Fluid balance and body weight fluctuation within 24 and 48 hours before extubation and from admission to planned extubation were calculated. The primary outcome was extubation failure (ie, all-cause reintubation within 72 hours). The association of extubation failure with fluid balance and body weight change was assessed via logistic regression analysis. Results: Extubation failure occurred in 12(7.4%)/161 patients. The extubation success group had a significantly lower fluid balance within 24 hours before extubation than did the extubation failure group (−276 mL [−1111 to 456] vs 1217 mL [503 to 1875], P = .002). However, fluid balance within 48 hours before extubation, cumulative fluid balance, and body weight change were not significantly different between the 2 groups. The sensitivity and specificity of water balance +1000 mL within 24 hours before extubation for the extubation failure group were 0.54 and 0.84, respectively, based on the receiver operating characteristic curve. Logistic regression analysis showed that fluid balance within 24 hours before extubation was associated with extubation failure (odds ratio: 22.9, 95% confidence interval: 4.1-128.4). Conclusions: A larger fluid balance within 24 hours before extubation is associated with extubation failure. Thus, fluid balance may be a good indicator of extubation outcome.

scholarly journals Weight Loss Medications in Young Adults after Bariatric Surgery for Weight Regain or Inadequate Weight Loss: A Multi-Center Study

Children ◽  
2018 ◽  
Vol 5 (9) ◽  
pp. 116 ◽  
Author(s):  
Alexander Toth ◽  
Gricelda Gomez ◽  
Alpana Shukla ◽  
Janey Pratt ◽  
Hellas Cena ◽  
...  
Keyword(s):  
Weight Loss ◽  
Young Adults ◽  
Body Weight ◽  
Weight Change ◽  
Weight Regain ◽  
Body Weight Loss ◽  
Total Body Weight ◽  
Percent Weight Loss ◽  
Total Body ◽  
Weight Loss Medications

This paper presents a retrospective cohort study of weight loss medications in young adults aged 21 to 30 following Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) between November 2000 and June 2014. Data were collected from patients who used topiramate, phentermine, and/or metformin postoperatively. Percentage of patients achieving ≥5%, ≥10%, or ≥15% weight loss on medications was determined and percent weight change on each medication was compared to percent weight change of the rest of the cohort. Our results showed that 54.1% of study patients lost ≥5% of their postsurgical weight; 34.3% and 22.9% lost ≥10% and ≥15%, respectively. RYGB had higher median percent weight loss (−8.1%) than SG (−3.3%) (p = 0.0515). No difference was found in median percent weight loss with medications started at weight plateau (−6.0%) versus after weight regain (−5.4%) (p = 0.5304). Patients taking medications at weight loss plateau lost 41.2% of total body weight from before surgery versus 27.1% after weight regain (p = 0.076). Median percent weight change on metformin was −2.9% compared to the rest of the cohort at −7.7% (p = 0.0241). No difference from the rest of the cohort was found for phentermine (p = 0.2018) or topiramate (p = 0.3187). Topiramate, phentermine, and metformin are promising weight loss medications for 21 to 30 year olds. RYGB patients achieve more weight loss on medications but both RYGB and SG benefit. Median total body weight loss from pre-surgical weight may be higher in patients that start medication at postsurgical nadir weight. Participants on metformin lost significantly smaller percentages of weight on medications, which could be the result of underlying medical conditions.

scholarly journals Analysis of cyclic feed intake in rats fed on a zinc-deficient diet and the level of dihydropyrimidinase (EC 3.5.2.2)

1995 ◽  
Vol 73 (5) ◽  
pp. 711-722 ◽  
Author(s):  
Nanaya Tamaki ◽  
Shigeko Fujimoto-Sakata ◽  
Mariko Kikugawa ◽  
Masae Kaneko ◽  
Satomi Onosaka ◽  
...  
Keyword(s):  
Body Weight ◽  
Feed Intake ◽  
Weight Change ◽  
The Body ◽  
Body Weight Change ◽  
Weight Changes ◽  
Deficient Diet ◽  
Cyclic Variations ◽  
Zinc Deficient Diet ◽  
And Control

The body weight and feed intake of rats fed on a Zn-deficient diet for 28 d were reduced compared with those of control rats. The feed intakes of the Zn-deficient and control groups during the period were 10·2 (SE 0·3) and 15·7 (SE 0·2) g/d respectively. Cyclic variations in feed intake and body-weight changes were found in analysis not only of all the data for five rats but also that in each individual rat. Cosinor analysis revealed that the cyclical period of both the feed intake and body-weight change in the Zn-deficient rats was 3·5 (SE 0·1) d. The mesor and amplitude value of the feed intake in the Zn-deficient rats was 10 1 (SE 0·4) g/d and 3·5 (SE 0·5) g/d respectively, and that of body-weight change was 1·4 (SE 0·1) g/d and 7·9 (SE 1·3) gObihiro d respectively. Among pyrimidine-catabolizing enzymes, dihydropyrimidinase (EC3.5.2.2) activity showed significantretardation in the Zn-deficient rat liver with decrease of the enzyme protein. The ratio of apo-form to holo-form dihydropyrimidinase in the liver was not affected by the Zn-deficient diet.

scholarly journals Perception of Weight changes among People with Depression SymptoCities in Indonesia

2019 ◽  
Author(s):  
Enung Nurchotimah ◽  
Rofingatul Mubasyiroh
Keyword(s):  
Body Weight ◽  
Low Income ◽  
Weight Change ◽  
Depressive Disorders ◽  
The Body ◽  
Depression Symptoms ◽  
Weight Changes ◽  
Body Weight Changes ◽  
Icd 10 ◽  
History Of

Background: Obesity is a growing problem so obesity is a threat to health, especially in a developing country like Indonesia. Obesity is a caused for death and burden of disease-causingvariousdiseases.Thisstudylookedatthecorrelationbetweenmental disorders associated with eating disorders or perceptions of changes in respondents’ weight toward depressive disorders. The perception to the body weight is one of the factors that are often found in symptoms of mental disorders. Objectives: This research aim to understand the individuals’ obesity condition picture of patients based on their characteristics. Methods: In this study individuals with depressive symptoms were established using MINI instruments through interviews using the ICD-10 Mini International Neuropsychiatric Interview Version mental health instrument conducted in October–November 2017 by nursing diploma enumerators who were trained by psychiatrists. The perception of the state of body weight obtained from sampling was carried out by stratified random sampling. This study is a further analysis of data on mentalhealthresearchconductedin3districts/citiesinIndonesia,namelyinthecityof Bogor,JombangandTojouna-Unadistrictsusingcrosssectionalmethod.Theresearch samplesanalyzedwereindividualswhoexperiencedsymptomsofdepression Results: From the 262 respondents who experienced a history of symptoms of depressive disorders, appetite disorders/changes in body weight experienced by majority of the respondents,amountingto66.0%.Asignificantrelationbetweengenderandownership economy level with the appetite disorder/body weight changes. Where women on lower economy level suffered from depression were highly probable risking appetite disorder/body weight changes experience. Conclusion: A majority of people with the depression symptoms history has the symptom of lack of appetite or the feel of the weight change. The symptom of lack of appetite/weight change happened to woman with depression and low income respondents.

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