Tumor with Aggregate Cells at the Level of Radial Distance Pipe - Treatment and Evolution

Abstract A 20-year-old patient presented to the emergency service with radial distal epiphysis after a minor trauma. The radiological examination indicated a fracture at the radial distal epiphysis on the background of a tumor that occupied the radial epiphysis in its entirety, with cortical burglary in some places. When consulting the oncologist, a surgical intervention for biopsy material harvesting was performed. The anatomopathological exam showed: multiple fragments microscopically representing a tumor proliferation consisting of two cell populations, mononuclear cells, densely cellular and strobe pattern; areas of infarction, haemorrhage areas, rare intratumoral osteoid formation zones; appearance of giant cell tumor. The immunohistochemical examination confirmed the anatomopathological diagnosis adding, therefore, the aggressive character and the local relapse. The oncologist decided that it did not require oncology treatment but only orthopedic treatment. Orthopedic treatment required repeated surgery at intervals of about 5 months apart, caused by tumor recurrence. The first intervention consisted of 1/ 3 distal radius resection and replacement with a graft harvested from the peroneum. Tumor recurrence after 5 months required extirpation of tumor tissue and filling of caries caused in the graft with a fluid bone substitute. Recurrence after another 5 months required removal of the graft that was invaded by the tumor and cubitusmetacarpal arthrodesis fixed with a screw plate. Currently, the patient is undergoing complementary oncology treatment finally initiated by a medical oncologist.

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“Endolymphatic Sacitis” in a Case of Active Meniere's Disease

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949710600303 ◽

1997 ◽

Vol 106 (3) ◽

pp. 190-198 ◽

Cited By ~ 32

Author(s):

Niklas Danckwardt-Lillieström ◽

Anders Kinnefors ◽

Ulla Frtoerg ◽

Helge Rask-Andersen

Keyword(s):

Mononuclear Cells ◽

Vascular Anatomy ◽

Meniere’S Disease ◽

Menière’S Disease ◽

Meniere's Disease ◽

Ménière’S Disease ◽

Menière's Disease ◽

Biopsy Material ◽

Acoustic Neuromas ◽

Ménière's Disease

An ultrastructural analysis of an entire intraosseous endolymphatic sac (ES) from a patient with active, well-documented Meniere's disease was performed for the first time. The results were compared with those obtained from ES biopsy material from patients with acoustic neuromas. The ES was small in size and showed signs of focal inflammation with intraepithelial invasion by mononuclear cells. At these places the normal fine structure, including the vascular anatomy, was altered. The possible relationship between these changes and Meniere's disease is discussed.

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SIS therapy in the treatment of distal radius epiphyseal fracture (Case report)

Balneo and PRM Research Journal ◽

10.12680/balneo.2021.460 ◽

2021 ◽

pp. 333-336

Author(s):

Diana JIMBU ◽

Doinița OPREA ◽

Emre SARIKAYA ◽

Mădălina Gabriela ILIESCU ◽

Elena Valentina IONESCU ◽

...

Keyword(s):

Cervical Spine ◽

Distal Radius ◽

Upper Limb ◽

Healing Process ◽

Orthopedic Treatment ◽

Inductive System ◽

Epiphyseal Fracture ◽

Distal Epiphysis ◽

Minimal Trauma ◽

The Right

Introduction. Fractures of the distal radius epiphysis are the most common fractures of the upper limb, present both in the general population active following major trauma and in the elderly population in minimal trauma due to osteoporosis. Among the adjuvant therapies for orthopedic treatment of distal radius epiphyseal fracture we can list Super Inductive System (SIS), a therapy based on the interaction between the electric field and the human body with the improvement of the healing process by acting on the pathophysiological stages of bone callus. Material and method. A clinical case study was performed on a 28-year-old patient, hospitalized and treated in the neurosurgery department of the Constanta County and Emergency Hospital for a polytrauma by road accident (passenger) with amyelotic cervical vertebral trauma, thoracic trauma and trauma to the right upper limb, subsequently performing 12 SIS therapy sessions at the Balneal and Rehabilitation Sanatorium of Techirghiol. CT examination of the cervical spine reveals fractures of C4 vertebra (the blade and pedicle) and C5 vertebra (vertebral body, lamina and pedicle). Right forearm radiography reveals fracture of the right radial styloid. After conservative treatment of the cervical injury and orthopedic treatment of the upper limb injury, the clinical evolution is favorable, allowing the patient to be discharged and allowed to do 12 sessions of SIS therapy, 3 times a week, within 4 weeks. The subsequent clinical and paraclinical evolution was favorable for the outpatient orthopedic ambulatory reevaluation performed at 5 weeks. Results and discussions. Due to the type of fracture of the radial distal epiphysis (linear fracture without displacement), absence of comorbidities and young age, led to the indication of orthopedic treatment with immobilization in the antebrachio-palmarcast, which allowed subsequent physiotherapy. Keywords: radial fracture, callus, polytrauma, cervical spine, lamina, Super Inductive System,

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Ultrastructural diagnosis of plasmacytoma on a fine-needle aspirate

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100084818 ◽

1991 ◽

Vol 49 ◽

pp. 102-103

Author(s):

S. Siew ◽

W. deMendonca-Calaca

Keyword(s):

Mononuclear Cells ◽

Fibrous Tissue ◽

Needle Aspiration ◽

Focal Lesions ◽

Diffuse Infiltration ◽

Fine Needle ◽

Cytoplasmic Vacuolation ◽

Chest Mass ◽

Mitotic Figures ◽

Microscopy Examination

A 36 year old man presented with a mass in the chest and multiple “hot” focal lesions were identified on bone scan. Fine needle aspiration was performed of the chest mass. Routine histology showed the presence of some bundles of dense fibrous tissue and a diffuse infiltration of mononuclear cells, which varied in size and nucleo-cytoplasmic ratio. The smaller cells had eccentric hyperchromatic nuclei. Nucleoli were noted in the larger cells. There was well marked cytoplasmic vacuolation of some of the cells. Mitosis was present. A small fragment of tissue was received for electron microscopy. Examination of 1 μm sections showed trabeculae of medium-large polygonal cells with eccentric nuclei and occasional nucleoli. Some irregularly shaped cells had well marked cytoplasmic vacuolation. Mitotic figures were present.

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The blister of porphyria cutanea tarda: A Scanning and Transmission Electron Microscopic study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100143298 ◽

1986 ◽

Vol 44 ◽

pp. 334-335

Author(s):

Veronika Burmeister ◽

R. Swaminathan

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Basement Membrane ◽

Middle Age ◽

Porphyria Cutanea Tarda ◽

Minor Trauma ◽

Electron Microscopic ◽

Transmission Electron Microscopic Study ◽

Transmission Electron ◽

Transmission Electron Microscopic

Porphyria cutanea tarda (PCT) is a disorder of porphyrin metabolism which occurs most often during middle age. The disease is characterized by excessive production of uroporphyrin which causes photosensitivity and skin eruptions on hands and arms, due to minor trauma and exposure to sunlight. The pathology of the blister is well known, being subepidermal with epidermodermal separation, it is not always absolutely clear, whether the basal lamina is attached to the epidermis or the dermis. The purpose of our investigation was to study the attachment of the basement membrane in the blister by comparing scanning with transmission electron microscopy.

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