scholarly journals Amination-reduction reaction as simple protocol for potential boronic molecular receptors. Insight in supramolecular structure directed by weak interactions

2011 ◽  
Vol 9 (2) ◽  
pp. 199-205 ◽  
Author(s):  
Agnieszka Adamczyk-Woźniak ◽  
Izabela Madura ◽  
Alicja Pawełko ◽  
Andrzej Sporzyński ◽  
Anna Żubrowska ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Weak Interactions ◽  
Layer Structure ◽  
Phenylboronic Acid ◽  
Reduction Reaction ◽  
Significant Rise ◽  
Molecular Receptors ◽  
Simple Protocol ◽  
Phenylboronic Acids ◽  
Insight Into

AbstractThe synthesis of the potential molecular receptors in the amination-reduction reaction has been investigated within the model system comprising (2-formylphenyl)boronic acid and morpholine. The 3-amine substituted benzoxaborole was identified to be the intermediate of the synthesis and the unsubstituted benzoxaborole as the by-product resulting from reduction of the starting material. The insight into the reactivity of the starting materials as well as the intermediate benzoxaborole enabled significant rise in the yield of 2-(aminomethyl) phenylboronic acids synthesis. The solid state structure of 2-(piperidylmethyl)phenylboronic acid has been re-determined, and the description of the molecule and the crystal is given. The supramolecular layer structure directed by the weak C-H…O and C-H…π interactions was identified and scrutinized based on the geometry and Hirshfeld surface analyses

scholarly journals Fast and Sensitive Bacteria Detection by Boronic Acid Modified Fluorescent Dendrimer

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3115
Author(s):  
Ayame Mikagi ◽  
Riho Tsurufusa ◽  
Yuji Tsuchido ◽  
Takeshi Hashimoto ◽  
Takashi Hayashita
Keyword(s):  
Boronic Acid ◽  
Electrostatic Interactions ◽  
Detection Method ◽  
Phenylboronic Acid ◽  
Bacteria Detection ◽  
Gram Negative Bacteria ◽  
Recognition Method ◽  
Dansyl Group ◽  
Colony Forming Units ◽  
Phenylboronic Acids

This study reports a novel, fast, easy, and sensitive detection method for bacteria which is urgently needed to diagnose infections in their early stages. Our work presents a complex of poly(amidoamine) dendrimer modified by phenylboronic acid and labeled by a fluorescent dansyl group (Dan-B8.5-PAMAM). Our system detects bacteria in 20 min with a sensitivity of approximately 104 colony-forming units (CFU)·mL−1. Moreover, it does not require any peculiar technical skills or expensive materials. The driving force for bacteria recognition is the binding between terminal phenylboronic acids on the probe and bacteria’s surface glycolipids, rather than electrostatic interactions. The aggregation caused by such binding reduces fluorescence. Even though our recognition method does not distinguish between live or dead bacteria, it shows selective antibacterial activity towards Gram-negative bacteria. This study may potentially contribute a new method for the convenient detection and killing of bacteria.

Using Quenching Kinetics and Thermodynamics of Amino-Fluorophores as Empirical Tools for Predicting Boronic Acid Sensors Suitable for Use in Physiological Conditions

2011 ◽  
Vol 64 (11) ◽  
pp. 1438 ◽  
Author(s):  
Nicholas McGregor ◽  
Christophe Pardin ◽  
W. G. Skene
Keyword(s):  
Electron Transfer ◽  
Fluorescence Quenching ◽  
Boronic Acid ◽  
Sulfonic Acid ◽  
Phenylboronic Acid ◽  
Water Soluble ◽  
Time Resolved ◽  
Diffusion Limited ◽  
Phenylboronic Acids ◽  
Acid Sensors

A series of water-soluble 1-amino-naphthalenes and 2-amino-fluorenes are prepared. These serve as model fluorophores for measuring the thermodynamics and kinetics of fluorescence quenching with phenylboronic acids and aliphatic amines. Steady-state and time-resolved fluorescence quenching kinetics are investigated using the Stern–Volmer method. Diffusion limited quenching constants and exergonic thermodynamics of electron transfer are derived for the 5-amino-1-napthol and 2-aminofluorene derivatives with phenylboronic acid and/or an aliphatic imine. No quenching and endergonic thermodynamics or electron transfer are observed for 5-sulfonamide, 5-sulfonic acid, or 5-hydroxy-7-sulfonic acid aminonaphthalene derivatives. Boronic acid sensors synthesized from these aminofluorophores by reductive amination with 2-formylphenylboronic acid undergo fluorescence revival in the presence of saccharides only when the fluorophore demonstrates diffusion limited quenching kinetics and exergonic thermodynamics of electron transfer with the boronic acid or imine quenchers. Thus, these two properties are suitable empirical tools for predicting saccharide-induced fluorescence revival of boronic acid sensors.

Fluorescent signaling provides deeper insight into aromatic anion uptake by metal-ion activated molecular receptors

2008 ◽  
Vol 32 (9) ◽  
pp. 1500 ◽  
Author(s):  
Adam J. Bradbury ◽  
Stephen F. Lincoln ◽  
Kevin P. Wainwright
Keyword(s):  
Metal Ion ◽  
Molecular Receptors ◽  
Insight Into ◽  
Anion Uptake

scholarly journals Edge screw withdrawal resistance in conventional particleboard and OSB: Influence of the particles type

2007 ◽  
pp. 109-117
Author(s):  
Jovan Miljkovic ◽  
Mladjan Popovic ◽  
Milanka Djiporovic-Momcilovic ◽  
Ivana Gavrilovic-Grmusa
Keyword(s):  
Oriented Strand Board ◽  
Layer Structure ◽  
Middle Layer ◽  
Root Diameter ◽  
Mean Values ◽  
Pilot Hole ◽  
Wood Particles ◽  
Screw Withdrawal ◽  
Insight Into

This research was based on presumption that the changes in size and shape of wood particles are expected to have certain impact on the particleboard quality in general. Since the conventional particleboard (PB) and oriented strand board (OSB) were built of the quite diverse wood particles, they present interesting specimens in the comparison tests. In this work, the influence of the wood particles type on the edge screw holding performance of conventional particleboard and OSB was investigated. Those tests were obtained with the screw diameters of 4.0 mm, 4.5 mm and 5 mm. Depth of embedment was 30 mm for all tests and with the pilot-hole diameter kept in the range of 80-90% in respect of the screw root diameter. Additional tests of the thickness density profile and tensile strength perpendicular to the surface of the board were conducted. Since the middle layer structure of the particleboard embeds the screw body, both mentioned parameters are considered important in the aspect of the quality of the edge screw holding performance. In order to have further insight into the conformation of the middle layer the image survey was obtained on the split board section presenting the surface of the middle layer. Significant differences in the SWR performance of OSB and PB was recorded at all screw diameters. For the screw withdrawal tests parameters OSB samples showed 56-73% superior mean values then conventional PB. On the other hand, the OSB showed wider dispersions of measured withdrawal forces at all screw diameters, which might present some of the problems in certain engineering and project calculations.

An insight into the electrochemical performance of La0.5−xPrxBa0.5CoO3−δ as cathodes for solid oxide fuel cells: study of the O2-reduction reaction

2018 ◽  
Vol 6 (34) ◽  
pp. 16699-16709 ◽  
Author(s):  
D. Garcés ◽  
H. Wang ◽  
S. A. Barnett ◽  
A. G. Leyva ◽  
F. R. Napolitano ◽  
...  
Keyword(s):  
Electrochemical Performance ◽  
Solid Oxide Fuel Cells ◽  
Polarization Resistance ◽  
Reduction Reaction ◽  
Solid Oxide ◽  
Electrode Polarization ◽  
Oxide Fuel ◽  
Resistance Response ◽  
O2 Reduction ◽  
Insight Into

The mechanism controlling the electrode polarization resistance response was studied for new LT-SOFC cathodes with La0.5−xPrxBa0.5CoO3−δ (0 ≤ x ≤ 0.5) compositions.

scholarly journals Insight into Weak Interactions between Carrier Proteins and their Substrates by Chemo-Enzymatic and Improved NMR Methods

2019 ◽  
Vol 116 (3) ◽  
pp. 67a
Author(s):  
Indrani Pal ◽  
Yousang Hwang ◽  
David Meyers ◽  
Dominique P. Frueh
Keyword(s):  
Weak Interactions ◽  
Carrier Proteins ◽  
Nmr Methods ◽  
Insight Into
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