scholarly journals Synchronous Manec (Mixedadeno-Neuroendocrine Carcinoma) of the Colon and Renal Cell Carcinoma – Case Report

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Bojan Milosevic ◽  
Nenad Markovic ◽  
Rade Markovic ◽  
Aleksandar Cvetkovic ◽  
Bojan Stojanovic ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Left Kidney ◽  
Diagnostic Procedures ◽  
Right Hemicolectomy ◽  
The Other ◽  
Synchronous Tumor ◽  
Carcinoma Of The Colon ◽  
Urinary Tract Disorders ◽  
Preoperative Diagnostic ◽  
Loss Of Appetite

Abstract Synchronous multiple carcinomas represent two or more primary carcinoma that occur sumultaneously in the same patient. In order to fulfill the condition that tumors are synchronous, each tumor must be primary and not a metastasis of another tumor. The occurrence of renal carcinoma synchronously with colonic carcinoma is not so common. On the other hand, the pathohistological image in rare cases shows a mixed glandular and neuroendocrine component described in earlier works. In this paper, we present a patient who made a colonoscopy, a biopsy from a tumor change in the cecum due to malady, fainting, loss of appetite, and a positive test for faecal occult bleeding, and confirmed that it is an adenocarcinoma of the cecum. Multi slise computerized tomography of the abdomen also described a tumor change in the uretero-pelocalrix system of the left kidney region. The patient had no urinary tract disorders. The diagnosis of the synchronous tumor of the cecum and left kidney was set. A right hemicolectomy with latero-lateral ileo-transverse anastomosis, as well as left nephroureterectomy, was performed. What is particularly interesting in this case is that the pathohistological picture of the cecum carcinoma shows a rare form of tumor tone, mixed adenoneuroendocrine carcinoma. In patients with diagnosed colorectal cancer, routine as well as additional preoperative diagnostic procedures should be performed to exclude the existence of kidney cancer, since, when synchronous with colorectal carcinoma occurs, renal carcinoma is mainly asymptomatic. In rare cases, the pathohistological picture may also show the neuroendocrine component of the tumor, which directs further therapy to the other direction.

Space reconstruction of the aneurysms of the vertebrobasilary confluence based on conventional angiography: Our experience

2008 ◽  
Vol 55 (2) ◽  
pp. 75-78
Author(s):  
I.M. Nikolic ◽  
M.Lj. Rakic ◽  
E.E. Slavik ◽  
G.M. Tasic ◽  
B.M. Djurovic ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Diagnostic Procedures ◽  
Conventional Angiography ◽  
Two Dimensional Image ◽  
Diagnostic Protocol ◽  
Clinical Center ◽  
Golden Standard ◽  
Preoperative Diagnostic ◽  
Third Dimension ◽  
Initial Results

Besides current development of the new diagnostic procedures conventional angiography still represents the golden standard in the diagnosing of intracranial aneurysms. Since it gives a two-dimensional image if the presentation of the third dimension is wanted it is necessary to apply appropriate algorithm structures and computers. In this study we show our experience in the application of space reconstruction of blood vessels and aneurysms of the vertebrobasilary confluence in 6 patients operated at the Institute for Neurosurgery, Clinical Center of Serbia. Intraoperative finding in all patients matched the finding that we got by space reconstruction of the blood vessels, which was possible to observe from different angles. Postoperative course in all patients was satisfying. Upon discharge the patients were without rough lateralization of the pyramidal system. Our initial results and their practical agreement with the interoperative finding give us right to recommend this method as the standard for the preoperative diagnostic protocol.

scholarly journals Autotransplantacija slezine

2002 ◽  
Vol 49 (3) ◽  
pp. 101-106 ◽  
Author(s):  
S. Knezevic ◽  
D. Stefanovic ◽  
M. Petrovic ◽  
Z. Djordjevic ◽  
Slavko Matic ◽  
...  
Keyword(s):  
Splenic Rupture ◽  
Left Kidney ◽  
The Other ◽  
Traumatic Rupture ◽  
Target Cells ◽  
Sodium Potassium ◽  
Abdominal Organs ◽  
The Right ◽  
Rupture Of The Spleen ◽  
Previous Disease

Auto transplantation of the spleen can be performed in the patients with traumatic rupture of the spleen, in whom spleen could not be conserved in the other way. The right indication for this method is isolated rupture of the spleen (concvasation or complete devascularisation). This method is not recommended in the endangered patients, patients with previous disease of the spleen as well as in the patients with the perforation of the other abdominal organs at the same time. Auto transplantation was performed in 12 patients with isolated splenic rupture and hematoperitoneum, 11 men and one woman. The majority of patients are younger. In 8 patients, autotransplantat was placed into big omentum, in three into lipomatous tissue surrounding left kidney, and in one into anterior abdominal wall. In all the patients from this group, following analysis were taken: MCV (middle volume of erythrocytes), HTC, Hb, Le, Glucose, urea, creatinin, sodium, potassium, alkali phosphatasis, target cells, Howell Jolly's bodies, Heinz's bodies, IgG, IgA, igM, C3, C4, T3, T4, T8, B, segmentated, eosinophiles, lymphocytes, reticulocytes, thrombocytes, fibrinogen, PT, APTT, aggregation of thrombocytes and aggregation of thrombocytes on collagen. The same parameters were taken in 12 patients with surgery similar to splenectomy and in 12 after splenectomy. After splenectomy, there was decrease of the immunologic defending abilities of the organism because of the loss of the clirens function of the spleen, decreased level of the opsonines and tutsin, which leads to the impaired phagocytosis, decreased concentration of IgM and T and B lymphocytes, while in patients after auto transplantation the results were physiological. The most important thing in the assessment of the function of the autotransplantated spleen is scintigraphic investigation using 99mTc-denaturated red blood cells. In our study, auto transplant function was assessed in 10/12 patients by scintigraphy. Five years after surgery no one patient was proved to have postsplenectomic sepsis.

scholarly journals Agave americana (Ketuke) toxicity in the kidney of Clarias batrachus

2018 ◽  
Vol 30 ◽  
pp. 244-247
Author(s):  
Archana Prasad ◽  
Rukmini Puri
Keyword(s):  
Behavioral Change ◽  
The Other ◽  
Clarias Batrachus ◽  
Epithelial Tissue ◽  
Renal Tubules ◽  
Histopathological Alterations ◽  
Agave Americana ◽  
Excessive Secretion ◽  
Loss Of Appetite ◽  
Different Parts

Different parts of plant have been used since many decades by humans for catching fishes. In this investigation, ‘ketuke ‘leaf effect was observed on behavioral change and histological alterations in the kidney of Clarias batrachus. Few fishes were kept as control i.e. not exposed to plant piscicide. The other fishes were exposed to 3gm per 30 liters of water for 24 and 48 hrs. In exposed fish’s restlessness, vigorous movement, excessive secretion of slime and loss of appetite was seen. Histologically, glomerular contraction, clumping of melanomacrophages, degeneration of epithelial tissue along with the degeneration of renal tubules and others were seen. Increase in the Bowman’s space was one of the noticeable changes. Extract accumulation was seen in the tissues. Exposure to sub lethal concentrations of Ketuke (Agave americana), caused duration dependent histopathological alterations in the kidney of Clarias batrachus which is discussed in the paper.

scholarly journals Constitutional Anemia (Fanconi’s Syndrome) and Leukemia in Two Brothers

Blood ◽  
1955 ◽  
Vol 10 (8) ◽  
pp. 788-801 ◽  
Author(s):  
R. H. COWDELL ◽  
P. J. R. PHIZACKERLEY ◽  
D. A. PYKE
Keyword(s):  
Bone Marrow ◽  
Acute Leukemia ◽  
Short Stature ◽  
Left Kidney ◽  
The Other ◽  
Congenital Defects ◽  
Fanconi’S Syndrome ◽  
Bone Marrow Hypoplasia ◽  
Fanconi's Syndrome ◽  
Hypoplastic Anemia

Abstract Two brothers physically very alike became ill in their third decade, one with severe bone marrow hypoplasia and the other with acute leukemia. Both died and the autopsy findings are described. The two shared certain congenital defects, notably short stature with small heads, cutaneous pigmentation, pituitary and genital hypoplasia, and deformity of the thumbs. The brother with hypoplastic anemia also had aortic hypoplasia and his left kidney was absent. No previous report has been discovered of the association of Fanconi’s syndrome (of bone marrow hypoplasia with congenital defects) and leukemia with similar congenital defects in brothers. In two reports of leukemia affecting cousins of patients with Fanconi's syndrome, the leukemic cousins were without congenital defects.

THE EFFECTS OF OESTROGENS AND OF MILD CHRONIC STARVATION ON THE WHITE RAT

1946 ◽  
Vol 24e (4) ◽  
pp. 105-118
Author(s):  
A. T. Cameron ◽  
Jean S. Guthrie ◽  
J. Carmichael
Keyword(s):  
Growth Rate ◽  
Oral Administration ◽  
Food Restriction ◽  
Marked Decrease ◽  
Pathological Change ◽  
The Other ◽  
Peanut Oil ◽  
Testicular Atrophy ◽  
Minor Degree ◽  
Loss Of Appetite

Daily injections of peanut oil for 17 or 18 days cause decrease in rate of growth of the rat, and testicular atrophy. Hence results in experiments in which peanut oil (and probably similar oils) are used as solvent vehicles for administration of material by injection may be misinterpreted. Oral administration of oestradiol (3 mgm. daily) to young mature rats for three weeks or more causes decrease in growth rate, relative decrease in size of kidneys, heart, spleen, muscle, and ovaries, little effect on the liver, marked decrease in size of testes, even to actual atrophy, and frequent enlargement of the adrenals in males, with occasional enlargement in females. The adrenals are discoloured to a maroon shade, whether enlarged or not, and evidence is advanced that they are undergoing a pathological change; any enlargement is not in the nature of hypertrophy. Oral administration of stilboestrol gives similar results. The general effects of oestrogens are more marked in male than in female animals. Loss of appetite and diminished food intake are among the general effects, but the mild chronic starvation so produced can only contribute in very minor degree to the other oestrogenic effects.In mild chronic starvation from food restriction the liver is invariably affected, while the adrenals are never enlarged nor discoloured.The effects of combined oestrogenic and thyroid administration seem to be neither additive nor truly antagonistic.

SPORADIC BILATERAL PAPILLARY RENAL CARCINOMA EXHIBITING C-MET MUTATION IN THE LEFT KIDNEY TUMOR

2000 ◽  
pp. 1241
Author(s):  
YASUYUKI TAKAKI ◽  
MUTSUO FURIHATA &NA; ◽  
CHIAKI YOSHIKAWA ◽  
TAKESHI KISHIDA ◽  
MASAHIRO YAO ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Left Kidney ◽  
Kidney Tumor

SPORADIC BILATERAL PAPILLARY RENAL CARCINOMA EXHIBITING C-MET MUTATION IN THE LEFT KIDNEY TUMOR

2000 ◽  
Vol 163 (4) ◽  
pp. 1241-1242 ◽  
Author(s):  
YASUYUKI TAKAKI ◽  
MUTSUO FURIHATA ◽  
CHIAKI YOSHIKAWA ◽  
TAKESHI KISHIDA ◽  
MASAHIRO YAO ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Left Kidney ◽  
Kidney Tumor

Guideline Compliance in Surgery for Thyroid Nodules – A Retrospective Study

2017 ◽  
Vol 125 (05) ◽  
pp. 327-334 ◽  
Author(s):  
A. Reinisch ◽  
P. Malkomes ◽  
N. Habbe ◽  
J. Bojunga ◽  
F. Grünwald ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Diagnostic Algorithm ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Thyroid Stimulating Hormone ◽  
University Hospital ◽  
Malignancy Rate ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology ◽  
Recommended Algorithm

Abstract Diagnostic guidelines for thyroid nodules focus on malignancy risk assessment to avoid unnecessary diagnostic operations. These guidelines recommend a combination of tests in form of a diagnostic algorithm. The present study analyzed the recommended algorithm and its implementation by different medical professionals. Preoperative diagnostic procedures, laboratory tests and histopathological findings of patients who underwent thyroid surgery between 2006 and 2013 were analyzed. The results were stratified by the assignation by specialized endocrinologists (ENP), general practitioners (GP) or Goethe-University Hospital Frankfurt (UKF). 677 patients were enrolled, of these 62% were assigned by UKF, 18.5% by an ENP and 19.5% by a GP. Ultrasonography rate was significantly higher in UKF (97.6%) compared to patients assigned by GP (90.9%, p<0.0001). Rates for fine-needle aspiration cytology ranged between 47.6% in UKF and 23.2% in ENP (p<0.0001). In over 93% of the patients an analysis of thyroid-stimulating hormone and triiodothyronine/thyroxin was realized. The overall malignancy rate was 11.82%. The malignancy rate was significantly higher if a FNA biopsy was performed (16.35 vs. 8.94%; p=0.0048). A higher malignancy rate could only be seen if the preoperative diagnostic workup included FNA. Besides this, the grade of algorithm adherence showed no effect on the malignancy rate.

scholarly journals Renal artery stenosis of atherosclerotic etiology – the single kidney surgical recurrence 12 years after nephrectomy

2016 ◽  
Vol 63 (3) ◽  
pp. 251-254
Author(s):  
Maria Daniela Tănăsescu ◽  
◽  
Marcel Pălămar ◽  
Mihai Ovidiu Comşa ◽  
Alexandru Mincă ◽  
...  
Keyword(s):  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Left Kidney ◽  
Secondary Hypertension ◽  
Artery Stenosis ◽  
The Other ◽  
Left Renal Artery ◽  
Arterial Blood ◽  
The Moment ◽  
The Right

Objectives. Renal artery stenosis, as main cause of renovascular secondary hypertension, is mainly caused by atherosclerosis of large vessels and is clinically characterized by resistant or malignant hypertension, impacting the kidney function to various degrees. The present article brings into attention the case of a patient which developed renal artery stenosis on the left kidney, the same condition occurring 12 years later on the right kidney. Material and method. Our patient was initially diagnosed at the age of 48 with complete occlusion of the left renal artery, for which left nephrectomy was performed, while the right artery was normal. Twelve years later she presents with renal artery stenosis on the right kidney, which is treat by stent-angioplasty. Results. After surgery, the patient’s evolution was positive, with amelioration of the laboratory values, in parallel to the arterial blood pressure. Discussions. The probability that, in the moment of diagnosis of renal artery stenosis with progressive evolution to occlusion caused by atherosclerosis, the other artery would be normal, both seen by ultrasonography and angiography, while years later to develop stenosis, is minimal. Up to present, the literature holds little evidence of such similar cases. Conclusions. In the particular case of patients that were diagnosed with severe renal artery stenosis of atherosclerotic origin and had only one of the arteries affected, it is necessary to keep a permanent monitoring, justified by the risk of development of the same pathology to the other artery

Sign in / Sign up

Export Citation Format

Share Document