Space reconstruction of the aneurysms of the vertebrobasilary confluence based on conventional angiography: Our experience

2008 ◽  
Vol 55 (2) ◽  
pp. 75-78
Author(s):  
I.M. Nikolic ◽  
M.Lj. Rakic ◽  
E.E. Slavik ◽  
G.M. Tasic ◽  
B.M. Djurovic ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Diagnostic Procedures ◽  
Conventional Angiography ◽  
Two Dimensional Image ◽  
Diagnostic Protocol ◽  
Clinical Center ◽  
Golden Standard ◽  
Preoperative Diagnostic ◽  
Third Dimension ◽  
Initial Results

Besides current development of the new diagnostic procedures conventional angiography still represents the golden standard in the diagnosing of intracranial aneurysms. Since it gives a two-dimensional image if the presentation of the third dimension is wanted it is necessary to apply appropriate algorithm structures and computers. In this study we show our experience in the application of space reconstruction of blood vessels and aneurysms of the vertebrobasilary confluence in 6 patients operated at the Institute for Neurosurgery, Clinical Center of Serbia. Intraoperative finding in all patients matched the finding that we got by space reconstruction of the blood vessels, which was possible to observe from different angles. Postoperative course in all patients was satisfying. Upon discharge the patients were without rough lateralization of the pyramidal system. Our initial results and their practical agreement with the interoperative finding give us right to recommend this method as the standard for the preoperative diagnostic protocol.

scholarly journals Assessing the quality of angiographic display of brain blood vessels aneurysms compared to intraoperative state

2013 ◽  
Vol 70 (12) ◽  
pp. 1117-1123 ◽  
Author(s):  
Igor Nikolic ◽  
Goran Tasic ◽  
Vladimir Jovanovic ◽  
Nikola Repac ◽  
Aleksandar Janicijevic ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Computed Tomographic Angiography ◽  
Conventional Angiography ◽  
Computed Tomographic ◽  
Advantages And Disadvantages ◽  
Spatial Reconstruction ◽  
Clinical Center ◽  
Preoperative Diagnostic ◽  
Clear Visibility ◽  
Tomographic Angiography

Background/Aim. Aneurysms in brain blood vessels are expanding bags composed of a neck, body and fundus. Clear visibility of the neck, the position of the aneurysm and surrounding structures are necessary for a proper choice of methods for excluding the aneurysm from the circulation. The aim of this study was to evaluate the reliability of spatial reconstruction of blood vessels of the brain based on the original software for 3D reconstruction of the equipment manufacturer and a personal computer model developed earlier in the Clinic for Neurosurgery, Clinical Center of Serbia, Belgrade, compared to intraoperative identification of these aneurysms. Methods. This study included 137 patients of both sexes. The presence of an aneurysm was verified by angiographic methods [computed tomographic angiography (CTA), multislice computed tomography angiography (MSCTA), magnetic resonance imaging angiography (MRA), or digital subtraction angiography (DSA)]. Results. The quality score (0 to 5) for CTA was 3.180 ? 0.961, MSCTA 4.062 ? 0.928, and for DSA 4.588 ? 0.758 (p < 0.01). The results of this study favorite conventional angiography as the gold standard for diagnostic of intracranial aneurysms. Conclusion. The results of this study are consistent with current publications review and clearly recognize the advantages and disadvantages of diagnostic neuroradiological procedures, with DSA of brain blood vessels as a binding preoperative diagnostic procedure in cases in who it is not possible to clearly visualize the supporting blood vessel and neck of the aneurysm by using the findings of CTA, MRA and MSCTA.

scholarly journals Non-atherosclerotic arteriopathy as the cause of ishemic stroke among young adults

2010 ◽  
Vol 63 (5-6) ◽  
pp. 324-332 ◽  
Author(s):  
Mirjana Jovicevic ◽  
Ivana Divjak ◽  
Petar Slankamenac ◽  
Aleksandar Jovanovic ◽  
Svetlana Ruzicka ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Magnetic Resonance ◽  
Systemic Vasculitis ◽  
Age Groups ◽  
Diagnostic Procedures ◽  
Carotid Artery Dissection ◽  
Doppler Imaging ◽  
Artery Dissection ◽  
Conventional Angiography ◽  
Clinical Center

The study comprised 100 ischemic stroke patients of both sexes aged 15-45 years who were treated at the Clinic of Neurology of the Clinical Center of Vojvodina in the period January 2001 - September 2004. All study subjects were divided into three age groups: 15-25, 26-35 and 36-45 years. Sex, age and risk factors for cerebrovascular disease were determined in all patients. Diagnostic procedures applied in all patients included brain computed tomography and/or magnetic resonance imaging, routine laboratory tests, Doppler imaging of extra and endocranial blood vessels and coagulation tests. Contrast and/or transesophageal echocardiography, immunological blood assays, magnetic resonance angiography and/or computed tomography angiography and/or conventional angiography, trombophilia markers, antiphospholipid antibodies and toxicological examination, etc. were performed in selected patients. Non-atherosclerotic arteriopathies were found in 8% of all study subjects, and were the most frequent cause of stroke in the age group 15-25. Carotid artery dissection was the most frequent diagnosis overall, found in 6% of all patients. Fibromuscular dysplasia and systemic vasculitis were diagnosed in one patient each. Moyamoya disease, Takayasu disease, infectious and isolated vasculitis of the CNS were not found in our patients.

scholarly journals Significance of the spatial reconstruction based on mathematical modeling in the surgical treatment of giant intracranial aneurysms

2006 ◽  
Vol 63 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Igor Nikolic ◽  
Mirjana Nagulic ◽  
Vaso Antunovic
Keyword(s):  
Blood Vessels ◽  
Intracranial Aneurysms ◽  
Giant Aneurysm ◽  
Diagnostic Procedures ◽  
Left Middle Cerebral Artery ◽  
Conventional Angiography ◽  
3 Dimensional ◽  
Giant Intracranial Aneurysms ◽  
Spatial Reconstruction ◽  
Dimensional Reconstruction

Background. The use of computer models for the 3- dimensional reconstruction could be a reliable method to overcome technical imperfections of diagnostic procedures for the microsurgical operation of giant intracranial aneurysms. Case report. We presented a case of successfully operated 52-year-old woman with giant intracranial aneurysm, in which the computer 3-dimensional reconstruction of blood vessels and the aneurysmal neck had been decisive for making the diagnosis. The model for 3- dimensional reconstruction of blood vessels was based on the two 2-dimensional projections of the conventional angiography. Standard neuroradiologic diagnostic procedures showed a giant aneurysm on the left middle cerebral artery, but the conventional subtraction and CT angiography did not reveal enough information. By the use of a personal computer, we performed a 3-dimensional spatial reconstruction of the left carotid artery to visualize the neck of aneurysm and its supplying blood vessels. Conclusion. The 3-dimensional spatial reconstruction of the cerebral vessels of a giant aneurysm based on the conventional angiography could be useful for planning the surgical procedure.

scholarly journals Meckel’s diverticulum: Acute abdomen in 8th decade of life

2011 ◽  
Vol 58 (3) ◽  
pp. 121-123
Author(s):  
Ranko Lazovic ◽  
Miodrag Radunovic ◽  
Vladimir Dobricanin
Keyword(s):  
Abdominal Pain ◽  
General Population ◽  
Abdominal Surgery ◽  
Intestinal Obstruction ◽  
Acute Abdomen ◽  
Diagnostic Procedures ◽  
Clinical Findings ◽  
Clinical Center ◽  
Preoperative Diagnostic

Meckel?s diverticulum represents one of the most common congenital anomalies of the gastrointestinal system. It appears in 1-3% of the general population. In this case study we presented 72 year old male patient who was admitted in the Center for abdominal surgery, Clinical Center of Montenegro. The symptoms were diffuse, severe abdominal pain, nausea and vomiting with intestinal obstruction. After the preoperative diagnostic procedures we performed resection of the terminal ileum and T-T anastomosis. Whenever the patient has the clinical findings of acute abdomen and no matter if patient is in elderly, we should think on complications of the Meckel?s diverticulum.

Optical Characterization of Silica Aerogel

1988 ◽  
Vol 121 ◽  
Author(s):  
Lawrence W. Hrubesh ◽  
Cynthia T. Alviso
Keyword(s):  
Silica Aerogel ◽  
Porous Silica ◽  
Optical Characterization ◽  
Optical Methods ◽  
Gradient Index ◽  
Two Dimensional ◽  
Two Dimensional Image ◽  
The Third ◽  
Third Dimension

ABSTRACTTwo optical methods are described for mapping the local variations of refractive index within monoliths of porous silica aerogel. One is an interferometrie measurement that produces “iso-index” fringes in a two dimensional image; an orthogonal view gives the third dimension information. The other method uses the deflection of a He-Ne laser beam to map the gradient index within a sample. The quantification of the measurements is described and the accuracy of the results is discussed.

scholarly journals Significance of punch biopsy and endocervical curretage in diagnostics of cervical intraepithelial lesions

2006 ◽  
Vol 63 (12) ◽  
pp. 995-999
Author(s):  
Milana Panjkovic ◽  
Tatjana Ivkovic-Kapicl
Keyword(s):  
Biopsy Specimen ◽  
Diagnostic Procedures ◽  
Punch Biopsy ◽  
Cervical Lesions ◽  
Diagnostic Protocol ◽  
Cervical Intraepithelial Lesions ◽  
Cone Biopsy ◽  
Intraepithelial Lesions ◽  
Exact Correlation ◽  
Cervical Conization

Background/Aim. Diagnostic procedures during the detection of cervical intraepithelial lesions (CIN) are a combination of cytology, colposcopy, punch biopsy and endocervical curretage. An optimal therapeutic approach according to the distribution, size and grade of cervical lesions is the result of this diagnostic protocol. This study was carried out to assess reliability of the punch biopsy and endocervical curretage in diagnostics of cervical intraepithelial lesions. Methods. Fifty patients undergoing cervical conization were studied retrospectively to evaluate the correlation between the grade of preoperative punch biopsy and endocervical curretage, and the grade of the dysplastic epithelial changes in the cone biopsy. CIN grade was established according to the WHO/ISGYP classification and comparation of the results was performed after that. Results. Out of the total number of patient, 89.36% of them with dysplastic epithelial changes on cone biopsy had also dysplastic changes in the preoperative punch biopsy. An exact correlation between CIN grades was identified in 56% of the cases, 20% in CIN2, and 36% in CIN3 cases. There were 24.14% patients with negative endocervical curretage, while only in one case the cone biopsy was negative, too. Among the remaining 22 patients with CIN changes in endocervical curretage specimens, only one had a negative cone biopsy. An exact correlation of CIN grade was identified in 37.93% of the cases, 13.79% of CIN2, and 24.14% of the CIN3 cases. Conclusion. There was a positive cor relation between the CIN grades in punch and cone biopsy, as well as between the grade on the endocervical curretage and cone biopsy specimen, but with the lower degree than previous.

scholarly journals Blood Vessels and Peripheral Nerves as Key Players in Cancer Progression and Therapy Resistance

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4471
Author(s):  
Niccolò Roda ◽  
Giada Blandano ◽  
Pier Giuseppe Pelicci
Keyword(s):  
Cancer Cells ◽  
Blood Vessels ◽  
Cancer Progression ◽  
Peripheral Nerves ◽  
Tumor Development ◽  
Therapy Resistance ◽  
Tumor Mass ◽  
Cancer Pathogenesis ◽  
Initial Results ◽  
Metastatic Spreading

Cancer cells continuously interact with the tumor microenvironment (TME), a heterogeneous milieu that surrounds the tumor mass and impinges on its phenotype. Among the components of the TME, blood vessels and peripheral nerves have been extensively studied in recent years for their prominent role in tumor development from tumor initiation. Cancer cells were shown to actively promote their own vascularization and innervation through the processes of angiogenesis and axonogenesis. Indeed, sprouting vessels and axons deliver several factors needed by cancer cells to survive and proliferate, including nutrients, oxygen, and growth signals, to the expanding tumor mass. Nerves and vessels are also fundamental for the process of metastatic spreading, as they provide both the pro-metastatic signals to the tumor and the scaffold through which cancer cells can reach distant organs. Not surprisingly, continuously growing attention is devoted to the development of therapies specifically targeting these structures, with promising initial results. In this review, we summarize the latest evidence that supports the importance of blood vessels and peripheral nerves in cancer pathogenesis, therapy resistance, and innovative treatments.

Guideline Compliance in Surgery for Thyroid Nodules – A Retrospective Study

2017 ◽  
Vol 125 (05) ◽  
pp. 327-334 ◽  
Author(s):  
A. Reinisch ◽  
P. Malkomes ◽  
N. Habbe ◽  
J. Bojunga ◽  
F. Grünwald ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Diagnostic Algorithm ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Thyroid Stimulating Hormone ◽  
University Hospital ◽  
Malignancy Rate ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology ◽  
Recommended Algorithm

Abstract Diagnostic guidelines for thyroid nodules focus on malignancy risk assessment to avoid unnecessary diagnostic operations. These guidelines recommend a combination of tests in form of a diagnostic algorithm. The present study analyzed the recommended algorithm and its implementation by different medical professionals. Preoperative diagnostic procedures, laboratory tests and histopathological findings of patients who underwent thyroid surgery between 2006 and 2013 were analyzed. The results were stratified by the assignation by specialized endocrinologists (ENP), general practitioners (GP) or Goethe-University Hospital Frankfurt (UKF). 677 patients were enrolled, of these 62% were assigned by UKF, 18.5% by an ENP and 19.5% by a GP. Ultrasonography rate was significantly higher in UKF (97.6%) compared to patients assigned by GP (90.9%, p<0.0001). Rates for fine-needle aspiration cytology ranged between 47.6% in UKF and 23.2% in ENP (p<0.0001). In over 93% of the patients an analysis of thyroid-stimulating hormone and triiodothyronine/thyroxin was realized. The overall malignancy rate was 11.82%. The malignancy rate was significantly higher if a FNA biopsy was performed (16.35 vs. 8.94%; p=0.0048). A higher malignancy rate could only be seen if the preoperative diagnostic workup included FNA. Besides this, the grade of algorithm adherence showed no effect on the malignancy rate.

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