scholarly journals Effects of Placental Extract on Cell Proliferation, Type I Collagen Production, and ALP Secretion in Human Osteosarcoma Cell Line Saos-2

2017 ◽  
Vol 26 (2) ◽  
pp. 157-160 ◽  
Author(s):  
Yasuhiro Imamura ◽  
Yoshitomo Honda ◽  
Kazuya Masuno ◽  
Hiroe Nakamura ◽  
Pao-Li Wang
Keyword(s):  
Cell Proliferation ◽  
Cell Line ◽  
Type I Collagen ◽  
Osteosarcoma Cell Line ◽  
Type I ◽  
Osteosarcoma Cell ◽  
Human Osteosarcoma Cell Line ◽  
Human Osteosarcoma ◽  
Human Osteosarcoma Cell ◽  
Placental Extract

Tannic acid enhances cisplatin effect on cell proliferation and apoptosis of human osteosarcoma cell line (U2OS)

2021 ◽  
Author(s):  
Mohamad Zahid Kasiram ◽  
Hermizi Hapidin ◽  
Hasmah Abdullah ◽  
Nor Munira Hashim ◽  
Ahmad Azlina ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Line ◽  
Tannic Acid ◽  
Osteosarcoma Cell Line ◽  
Osteosarcoma Cell ◽  
Human Osteosarcoma Cell Line ◽  
Human Osteosarcoma ◽  
Proliferation And Apoptosis ◽  
Human Osteosarcoma Cell

Recognition by cellular and humoral autologous immunity in a human osteosarcoma cell line

2003 ◽  
Vol 8 (4) ◽  
pp. 554-559 ◽  
Author(s):  
Yuki Nabeta ◽  
Kawaguchi Satoshi ◽  
Hiroeki Sahara ◽  
Hideyuki Ikeda ◽  
Yoshihiko Hirohashi ◽  
...  
Keyword(s):  
Cell Line ◽  
Osteosarcoma Cell Line ◽  
Osteosarcoma Cell ◽  
Human Osteosarcoma Cell Line ◽  
Human Osteosarcoma ◽  
Human Osteosarcoma Cell

Morphological characterization of a newly established human osteosarcoma cell line, HS-Os-1, revealing its distinct osteoblastic nature

1991 ◽  
Vol 60 (1) ◽  
pp. 181-187 ◽  
Author(s):  
Hiroshi Sonobe ◽  
Hiroo Mizobuchi ◽  
Yuiko Manabe ◽  
Mutsuo Furihata ◽  
Jun Iwata ◽  
...  
Keyword(s):  
Cell Line ◽  
Morphological Characterization ◽  
Osteosarcoma Cell Line ◽  
Osteosarcoma Cell ◽  
Human Osteosarcoma Cell Line ◽  
Human Osteosarcoma ◽  
Human Osteosarcoma Cell

scholarly journals Reversion of P-glycoprotein-mediated multidrug resistance by diallyl trisulfide in a human osteosarcoma cell line

2014 ◽  
Vol 31 (6) ◽  
pp. 2720-2726 ◽  
Author(s):  
ZHIYONG WANG ◽  
QING XIA ◽  
JIA CUI ◽  
YUTAO DIAO ◽  
JIANMIN LI
Keyword(s):  
Multidrug Resistance ◽  
Cell Line ◽  
Osteosarcoma Cell Line ◽  
Osteosarcoma Cell ◽  
Diallyl Trisulfide ◽  
Human Osteosarcoma Cell Line ◽  
Human Osteosarcoma ◽  
P Glycoprotein ◽  
Human Osteosarcoma Cell

scholarly journals Effect of Orento, a Traditional Japanese Medicine, on IL-6, IL-8 Secretion, Type 1 Collagen Production and Alkaline Phosphatase Secretion in the Human Osteosarcoma Cell Line Saos-2

Medicines ◽  
2020 ◽  
Vol 7 (10) ◽  
pp. 61
Author(s):  
Hourei Oh ◽  
Kazuya Masuno ◽  
Nobutaka Okusa ◽  
Yoshimasa Makita ◽  
Shin-ichi Fujiwara ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Cell Line ◽  
Osteosarcoma Cell Line ◽  
Osteosarcoma Cell ◽  
Human Osteosarcoma Cell Line ◽  
Collagen Production ◽  
Human Osteosarcoma ◽  
Traditional Japanese Medicine ◽  
Human Osteosarcoma Cell

Background: Orento, a traditional Japanese medicine, is known as Kampo medicine in Japan. We investigated the possible efficacy of Kampo medicine for periodontal disease. In this study, we examined the in vitro effects of orento on the proliferation of the inflammatory cytokines interleukin (IL)-6 and IL-8, the production of type 1 collagen, and the secretion of alkaline phosphatase (ALP) in the human osteosarcoma cell line Saos-2 (Saos-2 cells). Methods: The proliferation of Saos-2 cells was assessed by MTT assay. IL-6 and IL-8 levels, type 1 collagen production and ALP secretion were evaluated using enzyme-linked immunosorbent assay and ALP assays. Saos-2 cells were treated with or without 0.1, 1, 10, 100 and 1000 μg/mL of orento for 24 h. Results: Orento (10 μg/mL) significantly induced the proliferation of Saos-2 cells. At this concentration, orento suppressed IL-6 and IL-8 and enhanced type 1 collagen production and ALP secretion. Conclusions: These results indicate that orento controls the IL-6 and IL-8 secretion and cellular metabolism of osteoblasts, resulting in the secretion of early bone-related biomarkers.

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