HALLUCINATORY EXPERIENCES IN VISUALLY IMPAIRED INDIVIDUALS: CHARLES BONNET SYNDROME – IMPLICATIONS FOR RESEARCH AND CLINICAL PRACTICE

2018 ◽  
Vol 30 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Darija Jurisic ◽  
◽  
Irena Sesar ◽  
Ivan Cavar ◽  
Antonio Sesar ◽  
...  
2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
VimalKumar Paliwal ◽  
Ananya Das ◽  
GuttiNagendra Babu ◽  
Ankit Gupta ◽  
Vikas Kanaujia

2011 ◽  
Vol 26 (S2) ◽  
pp. 984-984
Author(s):  
A. Ghaffarinejad ◽  
F. Estilaee

Charles Bonnet syndrome (CBS) is an under-diagnosed and under-reported disorder that involves formal, persistent, vivid and complex visual hallucinations in visually impaired individuals.Some neurological, psychiatric and internal disorders such as major depressive disorder, panic disorder, multiple sclerosis, temporal arthritis, delirium and type II diabetes mellitus have been reported which occur concurrently with CBS.A 72-year-old woman with a slowly progressive tumor (probably astrocytoma) in her right parietal lobe which evaluated with MRI will be described. She presents new symptoms after 2 years. These symptoms were complex, well-formed and vivid visual hallucinations. These visions were dead acquaintances. Patient was seeing them with open eyes. Visions lasted for minutes to hours. She mentioned visions she saw when she was awake. She had recognized these hallucinatory experiences were not real.The etiology of CBS is not described well and it is not recognized where the pathologic site in the brain is. Cases with CBS and concurrent brain pathologies can help us finding these relations. This is the first report of concurrent CBS and astrocytoma in parietal lobe.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Bogusław Paradowski ◽  
Edyta Kowalczyk ◽  
Justyna Chojdak-Łukasiewicz ◽  
Aleksandra Loster-Niewińska ◽  
Monika Służewska-Niedźwiedź

Charles Bonnet syndrome is an underrecognized disease that involves visual hallucinations in visually impaired patients. We present the cases of three patients who experienced complex visual hallucinations following various pathomechanisms. In two cases, diagnosis showed coexistence of occipital lobe damage with ocular damage, while in the third case it showed occipital lobe damage with retrobulbar optic neuritis. Theories of pathogenesis and the neuroanatomical basis of complex visual hallucinations are discussed and supported by literature review.


2013 ◽  
Vol 04 (01) ◽  
pp. 63-65 ◽  
Author(s):  
Baba Awoye Issa ◽  
Abdullahi Dasliva Yussuf

ABSTRACTCharles Bonnet syndrome occurs in visually impaired but cognitively normal individuals. This report describes a condition of vivid visual hallucination (phantom images) in an 85‑year‑old conscious man, who had been blind by bilateral progressively worsening glaucoma. This common, but rarely reported, condition was managed by behavioral approach of repeated blinking, intermittent eyes closure, and reassurance. While emotional, mood and cognitive disorders need to be ruled out, the condition, though frightening to the afflicted, is benign and remediable with simple, inexpensive approach. Health workers managing people with terminal blindness should always ask for the presence of hallucinations from their patients to forestall a preventable distress resulting from wrong perception without visual stimulus.


2016 ◽  
Vol 236 (1) ◽  
pp. 48-52 ◽  
Author(s):  
Serhad Nalcaci ◽  
Orhan İlim ◽  
Zafer Oztas ◽  
Cezmi Akkin ◽  
Ahmet Acarer ◽  
...  

Purpose: The aim of this study is to investigate the prevalence and clinical characteristics of Charles Bonnet syndrome (CBS) in a group of Turkish patients with various retinal diseases. Methods: Two hundred and sixty-four patients with a best-corrected visual acuity of ≤20/40 in the better-seeing eye were asked with a standardized question whether they had symptoms of CBS. If they responded positively, a questionnaire was verbally administered to learn more about the details of the symptoms. Results: There were 125 (47.3%) females and 139 (52.7%) males with a mean age of 72.1 years (range 31-90). Seventeen (6.4%) patients were diagnosed with CBS. Three (17.7%) patients had noncomplex hallucinations and 14 (82.3%) had complex hallucinations. Conclusion: CBS is not uncommon in visually impaired patients with retinal disease. Clinicians who care for visually impaired patients should be aware of CBS.


2020 ◽  
Vol 48 (5) ◽  
pp. 2295-2305
Author(s):  
Jiawei Zhang ◽  
Dandan Li ◽  
Rui Zhang ◽  
Peng Gao ◽  
Rongxue Peng ◽  
...  

The role of miR-21 in the pathogenesis of various liver diseases, together with the possibility of detecting microRNA in the circulation, makes miR-21 a potential biomarker for noninvasive detection. In this review, we summarize the potential utility of extracellular miR-21 in the clinical management of hepatic disease patients and compared it with the current clinical practice. MiR-21 shows screening and prognostic value for liver cancer. In liver cirrhosis, miR-21 may serve as a biomarker for the differentiating diagnosis and prognosis. MiR-21 is also a potential biomarker for the severity of hepatitis. We elucidate the disease condition under which miR-21 testing can reach the expected performance. Though miR-21 is a key regulator of liver diseases, microRNAs coordinate with each other in the complex regulatory network. As a result, the performance of miR-21 is better when combined with other microRNAs or classical biomarkers under certain clinical circumstances.


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